Abstract
Most primary cutaneous squamous cell carcinomas are cured with surgery. A subset, however, may develop local and nodal metastasis that may eventuate in disease-specific; death. This subset has been variably termed high risk. Herein, we review; an emerging body of data on the risks of these outcomes and propose an evidence-based; risk stratification for low-, intermediate-, and high-risk tumors that takes into; account both tumor and patient characteristics. Finally, we discuss a framework for; management of these tumors on the basis of data, when available, and our; recommendations when data are sparse.
Original language | English (US) |
---|---|
Journal | Journal of the American Academy of Dermatology |
DOIs | |
State | Accepted/In press - 2017 |
Keywords
- Cutaneous squamous cell carcinoma
- Immunosuppression
- Management
- Radiotherapy
- Risk stratification
- Sentinel lymph node biopsy
- Staging
ASJC Scopus subject areas
- Dermatology