Abstract
Most primary cutaneous squamous cell carcinomas are cured with surgery. A subset, however, may develop local and nodal metastasis that may eventuate in disease-specific; death. This subset has been variably termed high risk. Herein, we review; an emerging body of data on the risks of these outcomes and propose an evidence-based; risk stratification for low-, intermediate-, and high-risk tumors that takes into; account both tumor and patient characteristics. Finally, we discuss a framework for; management of these tumors on the basis of data, when available, and our; recommendations when data are sparse.
| Original language | English (US) |
|---|---|
| Journal | Journal of the American Academy of Dermatology |
| DOIs | |
| State | Accepted/In press - 2017 |
Keywords
- Cutaneous squamous cell carcinoma
- Immunosuppression
- Management
- Radiotherapy
- Risk stratification
- Sentinel lymph node biopsy
- Staging
ASJC Scopus subject areas
- Dermatology
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Baum, C., Wright, A. C., Martinez, J. C., Arpey, C. J., Brewer, J. D., Roenigk, R. K., & Otley, C. C. (Accepted/In press). A new evidence-based risk stratification system for cutaneous squamous cell carcinoma into low, intermediate, and high risk groups with implications for management. Journal of the American Academy of Dermatology. https://doi.org/10.1016/j.jaad.2017.07.031