A multi-institutional review of endovenous thermal ablation of the saphenous vein finds male sex and use of anticoagulation are predictors of long-term failure

Young Erben; Isabel Vasquez; Yupeng Li; Peter Gloviczki; Manju Kalra; Gustavo Oderich; Randall R. De Martino; Haraldur Bjarnason; Melissa J. Neisen; January F. Moore; Joao A. Da Rocha-Franco; Maria C. Sanchez-Valenzuela; Gregory Frey; Beau Toskich; Zlatko Devcic; Houssam Farres; Warren A. Oldenburg; Jessica Gomez-Perez; Justin R. Yarbrough; Michael Adalia; William Stone; Andrew J. Meltzer; Albert G. Hakaim

doi:10.1177/0268355520972923

A multi-institutional review of endovenous thermal ablation of the saphenous vein finds male sex and use of anticoagulation are predictors of long-term failure

Young Erben, Isabel Vasquez, Yupeng Li, Peter Gloviczki, Manju Kalra, Gustavo Oderich, Randall R. De Martino, Haraldur Bjarnason, Melissa J. Neisen, January F. Moore, Joao A. Da Rocha-Franco, Maria C. Sanchez-Valenzuela, Gregory Frey, Beau Toskich, Zlatko Devcic, Houssam Farres, Warren A. Oldenburg, Jessica Gomez-Perez, Justin R. Yarbrough, Michael AdaliaWilliam Stone, Andrew J. Meltzer, Albert G. Hakaim

Research output: Contribution to journal › Article › peer-review

Abstract

Background: To review long-term outcomes and saphenous vein (SV) occlusion rate after endovenous ablation (EVA) for symptomatic varicose veins. Methods: A review of our EVA database (1998–2018) with at least 3-years of clinical and sonographic follow-up. The primary end point was SV closure rate. Results: 542 limbs were evaluated. 358 limbs had radiofrequency and 323 limbs had laser ablations; 542 great saphenous veins (GSV), 106 small saphenous veins (SSV) and 33 anterior accessory saphenous veins (AASV) were treated. Follow-up was 5.6 ± 2.3 years; 508 (74.6%) veins were occluded, 53 (7.8%) partially occluded and 120 (17.6%) were patent. On multivariable Cox regression analysis, male sex (HR 1.6, 95% CI [0.46–018], p = 0.012) and use anticoagulation (HR 2.0, 95% CI [0.69–0.34], p = 0.044) were predictors of long-term failure. On Kaplan-Meier curve, we had an 86.3% occlusion rate. Conclusion: Our experience revealed a 5-year closure rate of 86.3%. Ablations have satisfactory occlusion rate.

Original language	English (US)
Pages (from-to)	283-289
Number of pages	7
Journal	Phlebology
Volume	36
Issue number	4
DOIs	https://doi.org/10.1177/0268355520972923
State	Published - May 2021

Keywords

Venous disease
venous flow
venous reflux
venous severity score
venous stasis

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1177/0268355520972923

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Erben, Y., Vasquez, I., Li, Y., Gloviczki, P., Kalra, M., Oderich, G., De Martino, R. R., Bjarnason, H., Neisen, M. J., Moore, J. F., Da Rocha-Franco, J. A., Sanchez-Valenzuela, M. C., Frey, G., Toskich, B., Devcic, Z., Farres, H., Oldenburg, W. A., Gomez-Perez, J., Yarbrough, J. R., ... Hakaim, A. G. (2021). A multi-institutional review of endovenous thermal ablation of the saphenous vein finds male sex and use of anticoagulation are predictors of long-term failure. Phlebology, 36(4), 283-289. https://doi.org/10.1177/0268355520972923

Erben, Y, Vasquez, I, Li, Y, Gloviczki, P, Kalra, M, Oderich, G, De Martino, RR, Bjarnason, H, Neisen, MJ, Moore, JF, Da Rocha-Franco, JA, Sanchez-Valenzuela, MC, Frey, G, Toskich, B, Devcic, Z, Farres, H, Oldenburg, WA, Gomez-Perez, J, Yarbrough, JR, Adalia, M, Stone, W, Meltzer, AJ & Hakaim, AG 2021, 'A multi-institutional review of endovenous thermal ablation of the saphenous vein finds male sex and use of anticoagulation are predictors of long-term failure', Phlebology, vol. 36, no. 4, pp. 283-289. https://doi.org/10.1177/0268355520972923

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title = "A multi-institutional review of endovenous thermal ablation of the saphenous vein finds male sex and use of anticoagulation are predictors of long-term failure",

abstract = "Background: To review long-term outcomes and saphenous vein (SV) occlusion rate after endovenous ablation (EVA) for symptomatic varicose veins. Methods: A review of our EVA database (1998–2018) with at least 3-years of clinical and sonographic follow-up. The primary end point was SV closure rate. Results: 542 limbs were evaluated. 358 limbs had radiofrequency and 323 limbs had laser ablations; 542 great saphenous veins (GSV), 106 small saphenous veins (SSV) and 33 anterior accessory saphenous veins (AASV) were treated. Follow-up was 5.6 ± 2.3 years; 508 (74.6%) veins were occluded, 53 (7.8%) partially occluded and 120 (17.6%) were patent. On multivariable Cox regression analysis, male sex (HR 1.6, 95% CI [0.46–018], p = 0.012) and use anticoagulation (HR 2.0, 95% CI [0.69–0.34], p = 0.044) were predictors of long-term failure. On Kaplan-Meier curve, we had an 86.3% occlusion rate. Conclusion: Our experience revealed a 5-year closure rate of 86.3%. Ablations have satisfactory occlusion rate.",

keywords = "Venous disease, venous flow, venous reflux, venous severity score, venous stasis",

author = "Young Erben and Isabel Vasquez and Yupeng Li and Peter Gloviczki and Manju Kalra and Gustavo Oderich and {De Martino}, {Randall R.} and Haraldur Bjarnason and Neisen, {Melissa J.} and Moore, {January F.} and {Da Rocha-Franco}, {Joao A.} and Sanchez-Valenzuela, {Maria C.} and Gregory Frey and Beau Toskich and Zlatko Devcic and Houssam Farres and Oldenburg, {Warren A.} and Jessica Gomez-Perez and Yarbrough, {Justin R.} and Michael Adalia and William Stone and Meltzer, {Andrew J.} and Hakaim, {Albert G.}",

note = "Publisher Copyright: {\textcopyright} The Author(s) 2020.",

year = "2021",

month = may,

doi = "10.1177/0268355520972923",

language = "English (US)",

volume = "36",

pages = "283--289",

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T1 - A multi-institutional review of endovenous thermal ablation of the saphenous vein finds male sex and use of anticoagulation are predictors of long-term failure

AU - Erben, Young

AU - Vasquez, Isabel

AU - Li, Yupeng

AU - Gloviczki, Peter

AU - Kalra, Manju

AU - Oderich, Gustavo

AU - De Martino, Randall R.

AU - Bjarnason, Haraldur

AU - Neisen, Melissa J.

AU - Moore, January F.

AU - Da Rocha-Franco, Joao A.

AU - Sanchez-Valenzuela, Maria C.

AU - Frey, Gregory

AU - Toskich, Beau

AU - Devcic, Zlatko

AU - Farres, Houssam

AU - Oldenburg, Warren A.

AU - Gomez-Perez, Jessica

AU - Yarbrough, Justin R.

AU - Adalia, Michael

AU - Stone, William

AU - Meltzer, Andrew J.

AU - Hakaim, Albert G.

PY - 2021/5

Y1 - 2021/5

N2 - Background: To review long-term outcomes and saphenous vein (SV) occlusion rate after endovenous ablation (EVA) for symptomatic varicose veins. Methods: A review of our EVA database (1998–2018) with at least 3-years of clinical and sonographic follow-up. The primary end point was SV closure rate. Results: 542 limbs were evaluated. 358 limbs had radiofrequency and 323 limbs had laser ablations; 542 great saphenous veins (GSV), 106 small saphenous veins (SSV) and 33 anterior accessory saphenous veins (AASV) were treated. Follow-up was 5.6 ± 2.3 years; 508 (74.6%) veins were occluded, 53 (7.8%) partially occluded and 120 (17.6%) were patent. On multivariable Cox regression analysis, male sex (HR 1.6, 95% CI [0.46–018], p = 0.012) and use anticoagulation (HR 2.0, 95% CI [0.69–0.34], p = 0.044) were predictors of long-term failure. On Kaplan-Meier curve, we had an 86.3% occlusion rate. Conclusion: Our experience revealed a 5-year closure rate of 86.3%. Ablations have satisfactory occlusion rate.

AB - Background: To review long-term outcomes and saphenous vein (SV) occlusion rate after endovenous ablation (EVA) for symptomatic varicose veins. Methods: A review of our EVA database (1998–2018) with at least 3-years of clinical and sonographic follow-up. The primary end point was SV closure rate. Results: 542 limbs were evaluated. 358 limbs had radiofrequency and 323 limbs had laser ablations; 542 great saphenous veins (GSV), 106 small saphenous veins (SSV) and 33 anterior accessory saphenous veins (AASV) were treated. Follow-up was 5.6 ± 2.3 years; 508 (74.6%) veins were occluded, 53 (7.8%) partially occluded and 120 (17.6%) were patent. On multivariable Cox regression analysis, male sex (HR 1.6, 95% CI [0.46–018], p = 0.012) and use anticoagulation (HR 2.0, 95% CI [0.69–0.34], p = 0.044) were predictors of long-term failure. On Kaplan-Meier curve, we had an 86.3% occlusion rate. Conclusion: Our experience revealed a 5-year closure rate of 86.3%. Ablations have satisfactory occlusion rate.

KW - Venous disease

KW - venous flow

KW - venous reflux

KW - venous severity score

KW - venous stasis

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DO - 10.1177/0268355520972923

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AN - SCOPUS:85095951176

SN - 0268-3555

VL - 36

SP - 283

EP - 289

JO - Phlebology

JF - Phlebology

IS - 4

ER -

A multi-institutional review of endovenous thermal ablation of the saphenous vein finds male sex and use of anticoagulation are predictors of long-term failure

Abstract

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