A multi-institutional acute gastrointestinal toxicity analysis of anal cancer patients treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy

Kiran Devisetty, Loren K. Mell, Joseph K. Salama, David A. Schomas, Robert C. Miller, Ashesh B. Jani, John C. Roeske, Bulent Aydogan, Steven J. Chmura

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

Using previous dosimetric analysis methods, we identified the volume of bowel receiving 30 Gy (V30) correlated with acute gastrointestinal (GI) toxicity in anal cancer patients treated with intensity-modulated radiation therapy and concurrent chemotherapy. For V30 > 450 cc and ≤450 cc, acute GI toxicity was 33% and 8%, respectively (p = 0.003).

Original languageEnglish (US)
Pages (from-to)298-301
Number of pages4
JournalRadiotherapy and Oncology
Volume93
Issue number2
DOIs
StatePublished - Nov 2009

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Anus Neoplasms
Radiotherapy
Drug Therapy

Keywords

  • Anal cancer
  • Chemoradiotherapy
  • Dosimetric analysis
  • Gastrointestinal toxicity
  • IMRT

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Hematology

Cite this

A multi-institutional acute gastrointestinal toxicity analysis of anal cancer patients treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy. / Devisetty, Kiran; Mell, Loren K.; Salama, Joseph K.; Schomas, David A.; Miller, Robert C.; Jani, Ashesh B.; Roeske, John C.; Aydogan, Bulent; Chmura, Steven J.

In: Radiotherapy and Oncology, Vol. 93, No. 2, 11.2009, p. 298-301.

Research output: Contribution to journalArticle

Devisetty, Kiran ; Mell, Loren K. ; Salama, Joseph K. ; Schomas, David A. ; Miller, Robert C. ; Jani, Ashesh B. ; Roeske, John C. ; Aydogan, Bulent ; Chmura, Steven J. / A multi-institutional acute gastrointestinal toxicity analysis of anal cancer patients treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy. In: Radiotherapy and Oncology. 2009 ; Vol. 93, No. 2. pp. 298-301.
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