A multi-institutional acute gastrointestinal toxicity analysis of anal cancer patients treated with concurrent intensity-modulated radiation therapy (IMRT) and chemotherapy

Kiran Devisetty, Loren K. Mell, Joseph K. Salama, David A. Schomas, Robert C. Miller, Ashesh B. Jani, John C. Roeske, Bulent Aydogan, Steven J. Chmura

Research output: Contribution to journalArticle

54 Scopus citations


Using previous dosimetric analysis methods, we identified the volume of bowel receiving 30 Gy (V30) correlated with acute gastrointestinal (GI) toxicity in anal cancer patients treated with intensity-modulated radiation therapy and concurrent chemotherapy. For V30 > 450 cc and ≤450 cc, acute GI toxicity was 33% and 8%, respectively (p = 0.003).

Original languageEnglish (US)
Pages (from-to)298-301
Number of pages4
JournalRadiotherapy and Oncology
Issue number2
StatePublished - Nov 2009



  • Anal cancer
  • Chemoradiotherapy
  • Dosimetric analysis
  • Gastrointestinal toxicity
  • IMRT

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Hematology

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