A method for determination of stiffness of collagen molecules

Zong Ping Luo, Mark E. Bolander, Kai Nan An

Research output: Contribution to journalArticle

22 Scopus citations


This study developed a micromechanical test method for determination of stiffness of collagen molecules. The novelty includes the adoption of an optical tweezer system for loading a single collagen molecule and the development of a binding technique for gripping the collagen molecule termini for the micromechanical test. This methodology will potentially help us to understand the mechanical properties and functions of collagen ultrastructure.

Original languageEnglish (US)
Pages (from-to)251-254
Number of pages4
JournalBiochemical and Biophysical Research Communications
Issue number1
StatePublished - Mar 6 1997


ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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