A matched study of surgically treated stage IB adenosquamous carcinoma and adenocarcinoma of the uterine cervix

C. W. Helm, W. K. Kinney, Gary Keeney, W. D. Lawrence, T. S. Frank, H. Gore, R. K. Reynolds, S. J. Soong, E. E. Partridge, J. Roberts, K. Podratz, H. M. Shingleton

Research output: Contribution to journalArticle

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Abstract

Thirty-eight patients with surgically treated stage IB adenosquamous carcinoma of the uterine cervix (AS) have been matched with patients with other histologic subtypes of adenocarcinoma (A) for stage, lesion size, node status, grade of adenocarcinoma and age at diagnosis. An additional six patients with AS were unable to be matched. Overall 5-year survival and disease-free survival for the matched AS and A were not significantly different, 83 vs. 90%, and 78 vs. 81% nor were the number of recurrences, 8/38 AS vs. 6/38 A, but the mean time to recurrence was significantly shorter in the AS group: 11 vs. 32 months (P = 0.003). A subgroup of AS with a high risk of a poor outcome can be identified based on either lesion size ≥ 4 cm, depth of invasion ≥ 10 mm or pelvic lymph node metastasis. These patients may be suitable candidates for adjuvant therapy before or after surgical treatment.

Original languageEnglish (US)
Pages (from-to)245-249
Number of pages5
JournalInternational Journal of Gynecological Cancer
Volume3
Issue number4
DOIs
StatePublished - 1993

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Adenosquamous Carcinoma
Cervix Uteri
Adenocarcinoma
Recurrence
Disease-Free Survival
Lymph Nodes
Neoplasm Metastasis
Survival
Therapeutics

ASJC Scopus subject areas

  • Cancer Research
  • Obstetrics and Gynecology
  • Oncology

Cite this

A matched study of surgically treated stage IB adenosquamous carcinoma and adenocarcinoma of the uterine cervix. / Helm, C. W.; Kinney, W. K.; Keeney, Gary; Lawrence, W. D.; Frank, T. S.; Gore, H.; Reynolds, R. K.; Soong, S. J.; Partridge, E. E.; Roberts, J.; Podratz, K.; Shingleton, H. M.

In: International Journal of Gynecological Cancer, Vol. 3, No. 4, 1993, p. 245-249.

Research output: Contribution to journalArticle

Helm, CW, Kinney, WK, Keeney, G, Lawrence, WD, Frank, TS, Gore, H, Reynolds, RK, Soong, SJ, Partridge, EE, Roberts, J, Podratz, K & Shingleton, HM 1993, 'A matched study of surgically treated stage IB adenosquamous carcinoma and adenocarcinoma of the uterine cervix', International Journal of Gynecological Cancer, vol. 3, no. 4, pp. 245-249. https://doi.org/10.1046/j.1525-1438.1993.03040245.x
Helm, C. W. ; Kinney, W. K. ; Keeney, Gary ; Lawrence, W. D. ; Frank, T. S. ; Gore, H. ; Reynolds, R. K. ; Soong, S. J. ; Partridge, E. E. ; Roberts, J. ; Podratz, K. ; Shingleton, H. M. / A matched study of surgically treated stage IB adenosquamous carcinoma and adenocarcinoma of the uterine cervix. In: International Journal of Gynecological Cancer. 1993 ; Vol. 3, No. 4. pp. 245-249.
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AU - Reynolds, R. K.

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AU - Roberts, J.

AU - Podratz, K.

AU - Shingleton, H. M.

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