A matched study of surgically treated stage IB adenosquamous carcinoma and adenocarcinoma of the uterine cervix

C. W. Helm, W. K. Kinney, G. Keeney, W. D. Lawrence, T. S. Frank, H. Gore, R. K. Reynolds, S. ‐J Soong, E. E. Partridge, J. Roberts, K. Podratz, H. M. Shingleton

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Thirty‐eight patients with surgically treated stage IB adenosquamous carcinoma of the uterine cervix (AS) have been matched with patients with other histologic subtypes of adenocarcinoma (A) for stage, lesion size, node status, grade of adenocarcinoma and age at diagnosis. An additional six patients with AS were unable to be matched. Overall 5‐year survival and disease‐free survival for the matched AS and A were not significantly different, 83 vs. 90%, and 78 vs. 81% nor were the number of recurrences, 8/38 AS vs. 6/38 A, but the mean time to recurrence was significantly shorter in the AS group: 11 vs. 32 months (P = 0.003). A subgroup of AS with a high risk of a poor outcome can be identified based on either lesion size ≥ 4 cm, depth of invasion ≥ 10 mm or plevic lymph node metastasis. These patients may be suitable candidates for adjuvant therapy before or after surgical treatment.

Original languageEnglish (US)
Pages (from-to)245-249
Number of pages5
JournalInternational Journal of Gynecological Cancer
Volume3
Issue number4
DOIs
StatePublished - 1993

Keywords

  • adenocarcinoma
  • adenosquamous
  • carcinoma
  • cervix
  • prognosis
  • survival

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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    Helm, C. W., Kinney, W. K., Keeney, G., Lawrence, W. D., Frank, T. S., Gore, H., Reynolds, R. K., Soong, S. J., Partridge, E. E., Roberts, J., Podratz, K., & Shingleton, H. M. (1993). A matched study of surgically treated stage IB adenosquamous carcinoma and adenocarcinoma of the uterine cervix. International Journal of Gynecological Cancer, 3(4), 245-249. https://doi.org/10.1046/j.1525-1438.1993.03040245.x