A longitudinal study of speech fluency in aphasia: CT correlates of recovery and persistent nonfluency

David S. Knopman; Ola A. Selnes; Nancy Niccum; Alan B. Rubens; Douglas Yock; David Larson

doi:10.1212/wnl.33.9.1170

A longitudinal study of speech fluency in aphasia: CT correlates of recovery and persistent nonfluency

David S. Knopman, Ola A. Selnes, Nancy Niccum, Alan B. Rubens, Douglas Yock, David Larson

Neurology

Research output: Contribution to journal › Article › peer-review

85 Scopus citations

Abstract

The anatomic correlates of speech fluency were studied in 54 right-handed patients with aphasia due to stroke. Speech fluency was assessed at 1 month postonset and then monthly for 5 months. CTs obtained at 5 months postonset were used for lesion localization and volume determination. Persistent nonfluency was associated with lesions in the rolandic cortical region and underlying white matter. Recovery from nonfluency occurred in 6 of 27 patients. Lesions in these six patients were less extensive than lesions in patients with persistent nonfluency. Patients who were fluent by 1 month lacked extensive rolandic lesions.

Original language	English (US)
Pages (from-to)	1170-1178
Number of pages	9
Journal	Neurology
Volume	33
Issue number	9
DOIs	https://doi.org/10.1212/wnl.33.9.1170
State	Published - Sep 1983

ASJC Scopus subject areas

Clinical Neurology

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10.1212/wnl.33.9.1170

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abstract = "The anatomic correlates of speech fluency were studied in 54 right-handed patients with aphasia due to stroke. Speech fluency was assessed at 1 month postonset and then monthly for 5 months. CTs obtained at 5 months postonset were used for lesion localization and volume determination. Persistent nonfluency was associated with lesions in the rolandic cortical region and underlying white matter. Recovery from nonfluency occurred in 6 of 27 patients. Lesions in these six patients were less extensive than lesions in patients with persistent nonfluency. Patients who were fluent by 1 month lacked extensive rolandic lesions.",

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AU - Rubens, Alan B.

AU - Yock, Douglas

AU - Larson, David

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N2 - The anatomic correlates of speech fluency were studied in 54 right-handed patients with aphasia due to stroke. Speech fluency was assessed at 1 month postonset and then monthly for 5 months. CTs obtained at 5 months postonset were used for lesion localization and volume determination. Persistent nonfluency was associated with lesions in the rolandic cortical region and underlying white matter. Recovery from nonfluency occurred in 6 of 27 patients. Lesions in these six patients were less extensive than lesions in patients with persistent nonfluency. Patients who were fluent by 1 month lacked extensive rolandic lesions.

AB - The anatomic correlates of speech fluency were studied in 54 right-handed patients with aphasia due to stroke. Speech fluency was assessed at 1 month postonset and then monthly for 5 months. CTs obtained at 5 months postonset were used for lesion localization and volume determination. Persistent nonfluency was associated with lesions in the rolandic cortical region and underlying white matter. Recovery from nonfluency occurred in 6 of 27 patients. Lesions in these six patients were less extensive than lesions in patients with persistent nonfluency. Patients who were fluent by 1 month lacked extensive rolandic lesions.

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A longitudinal study of speech fluency in aphasia: CT correlates of recovery and persistent nonfluency

Abstract

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