A fistulating oropharyngeal lesion

Richard Heyes, Courtney M. Tomblinson, David G Lott

Research output: Contribution to journalArticlepeer-review

Abstract

Post-transplant lymphoproliferative disorder (PTLD) is a unifying term for a spectrum of lymphoid expansion entities brought about by immunosuppression. It can present throughout the head and neck, and tonsillar involvement is not limited to children. We report the case of a 67-year-old woman who developed odynophagia associated with putrid halitosis 4 months after she had undergone renal transplantation. Direct visualization of the oropharynx revealed multiple sites of severe ulceration and erythema, with erosion of both the anterior and posterior right tonsillar pillars and a necrotic ulceration fistulating deeply. Biopsy analysis led to a diagnosis of PTLD. The patient underwent rituximab monotherapy and responded well. However, after the cessation of therapy, she experienced a recurrence that necessitated chemotherapy, which resulted in a lasting remission. At follow-up 5 years later, she remained PTLD-free with stable stage 4 chronic kidney disease.

Original languageEnglish (US)
Pages (from-to)E15
JournalEar, Nose and Throat Journal
Volume97
Issue number12
DOIs
StatePublished - Dec 1 2018

ASJC Scopus subject areas

  • Otorhinolaryngology

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