A familial syndrome with cutaneous malignant melanoma and cerebral astrocytoma

D. K. Kaufman, D. W. Kimmel, J. E. Parisi, V. V. Michels

Research output: Contribution to journalArticlepeer-review

50 Scopus citations

Abstract

We describe a family in which cutaneous malignant melanoma or cerebral astrocytoma, or both, developed in eight members over three generations. Other malignancies also occurred with a lesser frequency. In two patients with both malignant melanoma and astrocytoma, the brain tumor followed the diagnosis of melanoma by a period of 2 and 10 years and was the primary cause of morbidity and mortality. The findings in this family may represent a newly described genetic disorder.

Original languageEnglish (US)
Pages (from-to)1728-1731
Number of pages4
JournalNeurology
Volume43
Issue number9
DOIs
StatePublished - 1993

ASJC Scopus subject areas

  • Clinical Neurology

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