A familial syndrome with cutaneous malignant melanoma and cerebral astrocytoma

D. K. Kaufman, D. W. Kimmel, Joseph E Parisi, V. V. Michels

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

We describe a family in which cutaneous malignant melanoma or cerebral astrocytoma, or both, developed in eight members over three generations. Other malignancies also occurred with a lesser frequency. In two patients with both malignant melanoma and astrocytoma, the brain tumor followed the diagnosis of melanoma by a period of 2 and 10 years and was the primary cause of morbidity and mortality. The findings in this family may represent a newly described genetic disorder.

Original languageEnglish (US)
Pages (from-to)1728-1731
Number of pages4
JournalNeurology
Volume43
Issue number9
StatePublished - 1993

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Melanoma
Inborn Genetic Diseases
Astrocytoma
Brain Neoplasms
Morbidity
Mortality
Neoplasms
Melanoma astrocytoma syndrome

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Kaufman, D. K., Kimmel, D. W., Parisi, J. E., & Michels, V. V. (1993). A familial syndrome with cutaneous malignant melanoma and cerebral astrocytoma. Neurology, 43(9), 1728-1731.

A familial syndrome with cutaneous malignant melanoma and cerebral astrocytoma. / Kaufman, D. K.; Kimmel, D. W.; Parisi, Joseph E; Michels, V. V.

In: Neurology, Vol. 43, No. 9, 1993, p. 1728-1731.

Research output: Contribution to journalArticle

Kaufman, DK, Kimmel, DW, Parisi, JE & Michels, VV 1993, 'A familial syndrome with cutaneous malignant melanoma and cerebral astrocytoma', Neurology, vol. 43, no. 9, pp. 1728-1731.
Kaufman DK, Kimmel DW, Parisi JE, Michels VV. A familial syndrome with cutaneous malignant melanoma and cerebral astrocytoma. Neurology. 1993;43(9):1728-1731.
Kaufman, D. K. ; Kimmel, D. W. ; Parisi, Joseph E ; Michels, V. V. / A familial syndrome with cutaneous malignant melanoma and cerebral astrocytoma. In: Neurology. 1993 ; Vol. 43, No. 9. pp. 1728-1731.
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