A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths

Dana L. Farkas; Noah J. Kolodziejski; Christopher J. Stapels; Daniel R. McAdams; Daniel E. Fernandez; Matthew J. Podolsky; James F. Christian; Brent B. Ward; Mark Vartarian; Stephen E. Feinberg; Seung Yup Lee; Urmi Parikh; Mary Ann Mycek; Michael J. Joyner; Christopher P. Johnson; Norman A. Paradis

doi:10.1117/12.2230988

A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths

Dana L. Farkas, Noah J. Kolodziejski, Christopher J. Stapels, Daniel R. McAdams, Daniel E. Fernandez, Matthew J. Podolsky, James F. Christian, Brent B. Ward, Mark Vartarian, Stephen E. Feinberg, Seung Yup Lee, Urmi Parikh, Mary Ann Mycek, Michael J. Joyner, Christopher P. Johnson, Norman A. Paradis

Anesthesiology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

5 Scopus citations

Abstract

Stable, relative localization of source and detection fibers is necessary for clinical implementation of quantitative optical perfusion monitoring methods such as diffuse correlation spectroscopy (DCS) and diffuse reflectance spectroscopy (DRS). A flexible and compact device design is presented as a platform for simultaneous monitoring of perfusion at a range of depths, enabled by precise location of optical fibers in a robust and secure adhesive patch. We will discuss preliminary data collected on human subjects in a lower body negative pressure model for hypovolemic shock. These data indicate that this method facilitates simple and stable simultaneous monitoring of perfusion at multiple depths and within multiple physiological compartments.

Original language	English (US)
Title of host publication	Optical Diagnostics and Sensing XVI
Subtitle of host publication	Toward Point-of-Care Diagnostics
Editors	Gerard L. Cote
Publisher	SPIE
ISBN (Electronic)	9781628419498
DOIs	https://doi.org/10.1117/12.2230988
State	Published - 2016
Event	Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics - San Francisco, United States Duration: Feb 15 2016 → Feb 16 2016

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	9715
ISSN (Print)	1605-7422

Other

Other	Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics
Country/Territory	United States
City	San Francisco
Period	2/15/16 → 2/16/16

Keywords

DCS
DRS
Optical perfusion monitoring
diffuse correlation spectroscopy
diffuse reflectance spectroscopy
hemorrhagic shock
noninvasive

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging
Biomaterials

Access to Document

10.1117/12.2230988

Cite this

Farkas, D. L., Kolodziejski, N. J., Stapels, C. J., McAdams, D. R., Fernandez, D. E., Podolsky, M. J., Christian, J. F., Ward, B. B., Vartarian, M., Feinberg, S. E., Lee, S. Y., Parikh, U., Mycek, M. A., Joyner, M. J., Johnson, C. P., & Paradis, N. A. (2016). A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths. In G. L. Cote (Ed.), Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics Article 97151H (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9715). SPIE. https://doi.org/10.1117/12.2230988

A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths. / Farkas, Dana L.; Kolodziejski, Noah J.; Stapels, Christopher J. et al.
Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics. ed. / Gerard L. Cote. SPIE, 2016. 97151H (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9715).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Farkas, DL, Kolodziejski, NJ, Stapels, CJ, McAdams, DR, Fernandez, DE, Podolsky, MJ, Christian, JF, Ward, BB, Vartarian, M, Feinberg, SE, Lee, SY, Parikh, U, Mycek, MA, Joyner, MJ, Johnson, CP & Paradis, NA 2016, A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths. in GL Cote (ed.), Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics., 97151H, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 9715, SPIE, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics, San Francisco, United States, 2/15/16. https://doi.org/10.1117/12.2230988

Farkas DL, Kolodziejski NJ, Stapels CJ, McAdams DR, Fernandez DE, Podolsky MJ et al. A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths. In Cote GL, editor, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics. SPIE. 2016. 97151H. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2230988

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abstract = "Stable, relative localization of source and detection fibers is necessary for clinical implementation of quantitative optical perfusion monitoring methods such as diffuse correlation spectroscopy (DCS) and diffuse reflectance spectroscopy (DRS). A flexible and compact device design is presented as a platform for simultaneous monitoring of perfusion at a range of depths, enabled by precise location of optical fibers in a robust and secure adhesive patch. We will discuss preliminary data collected on human subjects in a lower body negative pressure model for hypovolemic shock. These data indicate that this method facilitates simple and stable simultaneous monitoring of perfusion at multiple depths and within multiple physiological compartments.",

keywords = "DCS, DRS, Optical perfusion monitoring, diffuse correlation spectroscopy, diffuse reflectance spectroscopy, hemorrhagic shock, noninvasive",

author = "Farkas, {Dana L.} and Kolodziejski, {Noah J.} and Stapels, {Christopher J.} and McAdams, {Daniel R.} and Fernandez, {Daniel E.} and Podolsky, {Matthew J.} and Christian, {James F.} and Ward, {Brent B.} and Mark Vartarian and Feinberg, {Stephen E.} and Lee, {Seung Yup} and Urmi Parikh and Mycek, {Mary Ann} and Joyner, {Michael J.} and Johnson, {Christopher P.} and Paradis, {Norman A.}",

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AU - Christian, James F.

AU - Ward, Brent B.

AU - Vartarian, Mark

AU - Feinberg, Stephen E.

AU - Lee, Seung Yup

AU - Parikh, Urmi

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AB - Stable, relative localization of source and detection fibers is necessary for clinical implementation of quantitative optical perfusion monitoring methods such as diffuse correlation spectroscopy (DCS) and diffuse reflectance spectroscopy (DRS). A flexible and compact device design is presented as a platform for simultaneous monitoring of perfusion at a range of depths, enabled by precise location of optical fibers in a robust and secure adhesive patch. We will discuss preliminary data collected on human subjects in a lower body negative pressure model for hypovolemic shock. These data indicate that this method facilitates simple and stable simultaneous monitoring of perfusion at multiple depths and within multiple physiological compartments.

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A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths

Abstract

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Keywords

ASJC Scopus subject areas

Access to Document

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