A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths

Dana L. Farkas, Noah J. Kolodziejski, Christopher J. Stapels, Daniel R. McAdams, Daniel E. Fernandez, Matthew J. Podolsky, James F. Christian, Brent B. Ward, Mark Vartarian, Stephen E. Feinberg, Seung Yup Lee, Urmi Parikh, Mary Ann Mycek, Michael Joseph Joyner, Christopher P. Johnson, Norman A. Paradis

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

Stable, relative localization of source and detection fibers is necessary for clinical implementation of quantitative optical perfusion monitoring methods such as diffuse correlation spectroscopy (DCS) and diffuse reflectance spectroscopy (DRS). A flexible and compact device design is presented as a platform for simultaneous monitoring of perfusion at a range of depths, enabled by precise location of optical fibers in a robust and secure adhesive patch. We will discuss preliminary data collected on human subjects in a lower body negative pressure model for hypovolemic shock. These data indicate that this method facilitates simple and stable simultaneous monitoring of perfusion at multiple depths and within multiple physiological compartments.

Original languageEnglish (US)
Title of host publicationOptical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics
PublisherSPIE
Volume9715
ISBN (Electronic)9781628419498
DOIs
StatePublished - 2016
EventOptical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics - San Francisco, United States
Duration: Feb 15 2016Feb 16 2016

Other

OtherOptical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics
CountryUnited States
CitySan Francisco
Period2/15/162/16/16

Fingerprint

Skin
Perfusion
lower body negative pressure
Monitoring
Spectrum Analysis
Spectroscopy
Lower Body Negative Pressure
Equipment Design
Optical Fibers
compartments
Adhesives
adhesives
spectroscopy
Optical fibers
Shock
platforms
optical fibers
shock
reflectance
fibers

Keywords

  • DCS
  • diffuse correlation spectroscopy
  • diffuse reflectance spectroscopy
  • DRS
  • hemorrhagic shock
  • noninvasive
  • Optical perfusion monitoring

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Farkas, D. L., Kolodziejski, N. J., Stapels, C. J., McAdams, D. R., Fernandez, D. E., Podolsky, M. J., ... Paradis, N. A. (2016). A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths. In Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics (Vol. 9715). [97151H] SPIE. https://doi.org/10.1117/12.2230988

A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths. / Farkas, Dana L.; Kolodziejski, Noah J.; Stapels, Christopher J.; McAdams, Daniel R.; Fernandez, Daniel E.; Podolsky, Matthew J.; Christian, James F.; Ward, Brent B.; Vartarian, Mark; Feinberg, Stephen E.; Lee, Seung Yup; Parikh, Urmi; Mycek, Mary Ann; Joyner, Michael Joseph; Johnson, Christopher P.; Paradis, Norman A.

Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics. Vol. 9715 SPIE, 2016. 97151H.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Farkas, DL, Kolodziejski, NJ, Stapels, CJ, McAdams, DR, Fernandez, DE, Podolsky, MJ, Christian, JF, Ward, BB, Vartarian, M, Feinberg, SE, Lee, SY, Parikh, U, Mycek, MA, Joyner, MJ, Johnson, CP & Paradis, NA 2016, A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths. in Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics. vol. 9715, 97151H, SPIE, Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics, San Francisco, United States, 2/15/16. https://doi.org/10.1117/12.2230988
Farkas DL, Kolodziejski NJ, Stapels CJ, McAdams DR, Fernandez DE, Podolsky MJ et al. A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths. In Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics. Vol. 9715. SPIE. 2016. 97151H https://doi.org/10.1117/12.2230988
Farkas, Dana L. ; Kolodziejski, Noah J. ; Stapels, Christopher J. ; McAdams, Daniel R. ; Fernandez, Daniel E. ; Podolsky, Matthew J. ; Christian, James F. ; Ward, Brent B. ; Vartarian, Mark ; Feinberg, Stephen E. ; Lee, Seung Yup ; Parikh, Urmi ; Mycek, Mary Ann ; Joyner, Michael Joseph ; Johnson, Christopher P. ; Paradis, Norman A. / A disposable flexible skin patch for clinical optical perfusion monitoring at multiple depths. Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics. Vol. 9715 SPIE, 2016.
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