A Diagnostic Dilemma: Multiple Primary Intracranial Tumors Without Vestibular Schwannomas

Erynne A. Faucett, Brandon Larsen, Rihan Khan, Alexander G. Chiu, Eugene H. Chang

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Sinonasal schwannomas with intracranial extension are exceedingly rare, with only 7 cases reported in the literature. Schwannomas can be isolated or multiple and are commonly associated with familial disorders such as neurofibromatosis 2 (NF 2) or familial schwannomatosis or in sporadic cases seen in sporadic schwannomatosis. Nearly all people with NF2 older than 30 years of age will have the hallmark of bilateral vestibular schwannomas (VS). This case highlights a reported case of an adult with separate primary intracranial tumors. We review the diagnostic criteria of NF2 and schwannomatosis, a recently described third variant of neurofibromatosis. In this case, we incorporate family history, histopathology, and the pathophysiology of both disorders to help determine a diagnosis for this patient.

Original languageEnglish (US)
Pages (from-to)938-942
Number of pages5
JournalAnnals of Otology, Rhinology and Laryngology
Volume125
Issue number11
DOIs
StatePublished - Nov 1 2016
Externally publishedYes

Keywords

  • Neurofibromatosis
  • schwannoma
  • schwannomatosis
  • sinonasal tumor

ASJC Scopus subject areas

  • Otorhinolaryngology

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