A core review of temperature regimens and neuroprotection during cardiopulmonary bypass

Does rewarming rate matter?

Alina M. Grigore, Catherine Friederich Murray, Harish Ramakrishna, George Djaiani

Research output: Contribution to journalArticle

62 Citations (Scopus)

Abstract

Despite a half century of research and the implementation of various risk-reduction strategies among clinicians and basic scientists, patients continue to experience strokes and cognitive dysfunction related to the use of cardiopulmonary bypass (CPB) for cardiac surgery. One strategy to reduce these detrimental effects has been the use of hypothermia. Although numerous studies have addressed the issue, the question of whether the use of hypothermia during CPB attenuates the impact of central nervous system consequences remains unresolved. However, data clearly demonstrate that hyperthermia is to be avoided in the perioperative period, necessitating careful rewarming strategies if hypothermia is used during CPB. Selecting and understanding the impact of the temperature-monitoring site is important to accurately estimate cerebral temperature and to avoid inadvertent surges in brain temperature. In this article, we review the literature regarding the impact of hypothermia and rewarming rates during cardiac surgery.

Original languageEnglish (US)
Pages (from-to)1741-1751
Number of pages11
JournalAnesthesia and Analgesia
Volume109
Issue number6
DOIs
StatePublished - Dec 2009

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Rewarming
Hypothermia
Cardiopulmonary Bypass
Temperature
Thoracic Surgery
Perioperative Period
Risk Reduction Behavior
Fever
Central Nervous System
Stroke
Neuroprotection
Brain
Research

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

Cite this

A core review of temperature regimens and neuroprotection during cardiopulmonary bypass : Does rewarming rate matter? / Grigore, Alina M.; Murray, Catherine Friederich; Ramakrishna, Harish; Djaiani, George.

In: Anesthesia and Analgesia, Vol. 109, No. 6, 12.2009, p. 1741-1751.

Research output: Contribution to journalArticle

Grigore, Alina M. ; Murray, Catherine Friederich ; Ramakrishna, Harish ; Djaiani, George. / A core review of temperature regimens and neuroprotection during cardiopulmonary bypass : Does rewarming rate matter?. In: Anesthesia and Analgesia. 2009 ; Vol. 109, No. 6. pp. 1741-1751.
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