A configurable IC for wireless real-time in vivo monitoring of chemical and electrical neural activity.

Masoud Roham, Charles D. Blaha, Paul A. Garris, Kendall H. Lee, Pedram Mohseni

Research output: Contribution to journalArticle

Abstract

A 16-channel chip for wireless in vivo recording of chemical and electrical neural activity is described. The 7.83-mm2 IC is fabricated using a 0.5-microm CMOS process and incorporates a 71-microW, 3rd-order, configurable, DeltaSigma modulator per channel, achieving an input-referred noise of 4.69 microVrms in 4-kHz BW and 94.1 pArms in 5-kHz BW for electrical and fastscan voltammetric chemical neurosensing, respectively. Brain extracellular levels of dopamine elicited by electrical stimulation of the medial forebrain bundle have been recorded wirelessly on multiple channels using 300-V/s fast-scan cyclic voltammetry in the anesthetized rat.

Original languageEnglish (US)
Pages (from-to)4222-4225
Number of pages4
JournalConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
StatePublished - 2009
Externally publishedYes

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Medial Forebrain Bundle
Electric Stimulation
Noise
Dopamine
Monitoring
Brain
Modulators
Cyclic voltammetry
Rats

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

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AU - Mohseni, Pedram

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