TY - GEN
T1 - A configurable IC for wireless real-time in vivo monitoring of chemical and electrical neural activity
AU - Roham, Masoud
AU - Blaha, Charles D.
AU - Garris, Paul A.
AU - Lee, Kendall H.
AU - Mohseni, Pedram
PY - 2009
Y1 - 2009
N2 - A 16-channel chip for wireless in vivo recording of chemical and electrical neural activity is described. The 7.83-mm2 IC is fabricated using a 0.5-μm CMOS process and incorporates a 71-μW, 3rd-order, configurable, ΔΣ modulator per channel, achieving an input-referred noise of 4.69 μVrms in 4-kHz BW and 94.1 pArms in 5-kHz BW for electrical and fast-scan voltammetric chemical neurosensing, respectively. Brain extracellular levels of dopamine elicited by electrical stimulation of the medial forebrain bundle have been recorded wirelessly on multiple channels using 300-V/s fast-scan cyclic voltammetry in the anesthetized rat.
AB - A 16-channel chip for wireless in vivo recording of chemical and electrical neural activity is described. The 7.83-mm2 IC is fabricated using a 0.5-μm CMOS process and incorporates a 71-μW, 3rd-order, configurable, ΔΣ modulator per channel, achieving an input-referred noise of 4.69 μVrms in 4-kHz BW and 94.1 pArms in 5-kHz BW for electrical and fast-scan voltammetric chemical neurosensing, respectively. Brain extracellular levels of dopamine elicited by electrical stimulation of the medial forebrain bundle have been recorded wirelessly on multiple channels using 300-V/s fast-scan cyclic voltammetry in the anesthetized rat.
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U2 - 10.1109/IEMBS.2009.5333089
DO - 10.1109/IEMBS.2009.5333089
M3 - Conference contribution
C2 - 19963812
AN - SCOPUS:77950986109
SN - 9781424432967
T3 - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
SP - 4222
EP - 4225
BT - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
PB - IEEE Computer Society
T2 - 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Y2 - 2 September 2009 through 6 September 2009
ER -