Abstract
Timed matings of mice are often carried out to obtain offspring of a precise age when required for a study. Timed matings involve housing male and female mice together for a limited time period, typically overnight. A limitation of this practice is that many mouse pairs fail to mate during the brief co-housing period. The authors co-housed each breeding pair in the same cage but separated by a transparent partition for 3 d before carrying out timed matings. This co-housing strategy resulted in increased copulation during the timed mating period and also significantly increased the average number of pups produced per breeding pair. The authors suggest that co-housing likely permits male urine-borne pheromones to induce female estrus and also enables the expression of male and female mating behaviors.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 62-65 |
| Number of pages | 4 |
| Journal | Lab Animal |
| Volume | 42 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 2013 |
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ASJC Scopus subject areas
- Animal Science and Zoology
- veterinary(all)
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A co-housing strategy to improve fecundity of mice in timed matings. / Stiles, Robert J.; Schrum, Adam G.; Gil, Diana.
In: Lab Animal, Vol. 42, No. 2, 02.2013, p. 62-65.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A co-housing strategy to improve fecundity of mice in timed matings
AU - Stiles, Robert J.
AU - Schrum, Adam G.
AU - Gil, Diana
PY - 2013/2
Y1 - 2013/2
N2 - Timed matings of mice are often carried out to obtain offspring of a precise age when required for a study. Timed matings involve housing male and female mice together for a limited time period, typically overnight. A limitation of this practice is that many mouse pairs fail to mate during the brief co-housing period. The authors co-housed each breeding pair in the same cage but separated by a transparent partition for 3 d before carrying out timed matings. This co-housing strategy resulted in increased copulation during the timed mating period and also significantly increased the average number of pups produced per breeding pair. The authors suggest that co-housing likely permits male urine-borne pheromones to induce female estrus and also enables the expression of male and female mating behaviors.
AB - Timed matings of mice are often carried out to obtain offspring of a precise age when required for a study. Timed matings involve housing male and female mice together for a limited time period, typically overnight. A limitation of this practice is that many mouse pairs fail to mate during the brief co-housing period. The authors co-housed each breeding pair in the same cage but separated by a transparent partition for 3 d before carrying out timed matings. This co-housing strategy resulted in increased copulation during the timed mating period and also significantly increased the average number of pups produced per breeding pair. The authors suggest that co-housing likely permits male urine-borne pheromones to induce female estrus and also enables the expression of male and female mating behaviors.
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UR - http://www.scopus.com/inward/citedby.url?scp=84872981408&partnerID=8YFLogxK
U2 - 10.1038/laban.161
DO - 10.1038/laban.161
M3 - Article
C2 - 23340789
AN - SCOPUS:84872981408
VL - 42
SP - 62
EP - 65
JO - Lab Animal
JF - Lab Animal
SN - 0093-7355
IS - 2
ER -