A cerebellopontine angle craniopharyngioma in a patient with gardner's syndrome: Case report and review of the literature

A 29-year-old man with a history of Gardner's syndrome presented with a 1-year history of diplopia, right-sided hearing loss, right hypalgesia and dysphagia. A MRI scan revealed a large inhomogeneously enhancing, partially cystic lesion in the right cerebellopontine (CP) angle. There was faint calcification on CT and it was angiographically avascular. A right suboccipital craniotomy was performed with gross total resection of the tumor. The tumor appeared to originate from the right foramen of Luschka. The pathology was consistent with craniopharyngioma. This is only the third reported case of a craniopharyngioma of the CP angle. The pathogenesis and management for this rare occurrence is discussed. The genetics relating tumors in Gardner's syndrome and craniopharyngioma is also reviewed.