A case of peritoneal TB causing renal failure in a patient with rheumatoid arthritis and initial negative PPD after treatment with infliximab

Abhishek Sharma, Divyanshu Dubey, Kalyan Janga, Sheldon Greenberg

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Opportunistic infection and reactivation of latent infection has been reported with use of monoclonal TNF alpha antibodies used for treatment of severe rheumatoid arthritis. We present a case of peritoneal tuberculosis (TB) causing renal failure secondary to ureteral constriction in a patient who had been treated with infliximab for rheumatoid arthritis. We suggest that physicians should be aware of the increased risk of false negative and false positive TST and IGRA among patients treated with monoclonal TNF alpha antibodies and should regularly look for usual and unusual symptoms of TB in this patient population.

Original languageEnglish (US)
Pages (from-to)948-950
Number of pages3
JournalRenal Failure
Volume36
Issue number6
DOIs
StatePublished - Jan 1 2014
Externally publishedYes

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Keywords

  • Monoclonal TNF alpha antibodies
  • Renal failure
  • Tuberculosis

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Nephrology

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