A case of pancreatitis, panniculitis and polyarthritis syndrome: Elucidating the pathophysiologic mechanisms of a rare condition

Ines Loverdos, Marc C. Swan, Shant Shekherdimian, Abdulrahman A. Al-Rasheed, Rayfel Schneider, Joel S. Fish, Bo Yee Ngan, Khosrow Adeli, Mark E. Lowe, Vijay Prem Singh, Wednesday Marie A Sevilla, Jacob C. Langer, Tanja Gonska

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

Pancreatitis-Panniculitis-Polyarthritis (PPP) syndrome is rare and its physiopathology unclear. A 6-year old boy suffered of traumatic pancreatitis complicated by PPP syndrome. Extensive investigations demonstrated high levels of pancreatic lipase and fatty acids in the affected peripheral tissues. These findings support the sequence of peripheral lipolysis and fatty acid accumulation inducing tissue inflammation.

Original languageEnglish (US)
Pages (from-to)223-226
Number of pages4
JournalJournal of Pediatric Surgery Case Reports
Volume3
Issue number5
DOIs
StatePublished - May 1 2015

Keywords

  • Complicated pancreatitis
  • Key words Pancreatitis, panniculitis and polyarthritis syndrome
  • Pediatric pancreatitis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

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    Loverdos, I., Swan, M. C., Shekherdimian, S., Al-Rasheed, A. A., Schneider, R., Fish, J. S., Ngan, B. Y., Adeli, K., Lowe, M. E., Singh, V. P., Sevilla, W. M. A., Langer, J. C., & Gonska, T. (2015). A case of pancreatitis, panniculitis and polyarthritis syndrome: Elucidating the pathophysiologic mechanisms of a rare condition. Journal of Pediatric Surgery Case Reports, 3(5), 223-226. https://doi.org/10.1016/j.epsc.2015.03.014