A bone marrow biopsy technique suitable for use in neonates

Martha C. Sola, Lisa Rimsza, Robert D. Christensen

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Thrombocytopenia and neutropenia are common among neonates in intensive care units. Bone marrow aspirations are sometimes performed as part of their evaluation. However, marrow biopsies have not been reported from living neonates. Since architecture and cellularity cannot generally be accurately assessed from marrow aspirates, we devised a biopsy technique which we successfully applied to five cytopenic neonates (three with severe persistent thrombocytopenia and two with idiopathic neutropenia). This technique used a 19 gauge, half-inch Osgood needle to obtain bone marrow clots from the tibias of small preterm neonates which enabled the assessment of marrow cellularity and architecture. On the basis of our initial experience we have ceased using the traditional bone marrow aspiration technique in neonates and now use this technique exclusively.

Original languageEnglish (US)
Pages (from-to)458-460
Number of pages3
JournalBritish Journal of Haematology
Volume107
Issue number2
DOIs
StatePublished - 1999
Externally publishedYes

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Bone Marrow
Biopsy
Neutropenia
Thrombocytopenia
Tibia
Needles
Intensive Care Units

Keywords

  • Biopsy
  • Marrow
  • Newborn infant

ASJC Scopus subject areas

  • Hematology

Cite this

A bone marrow biopsy technique suitable for use in neonates. / Sola, Martha C.; Rimsza, Lisa; Christensen, Robert D.

In: British Journal of Haematology, Vol. 107, No. 2, 1999, p. 458-460.

Research output: Contribution to journalArticle

Sola, Martha C. ; Rimsza, Lisa ; Christensen, Robert D. / A bone marrow biopsy technique suitable for use in neonates. In: British Journal of Haematology. 1999 ; Vol. 107, No. 2. pp. 458-460.
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