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  • Clifford R Jr. Jack
Article

[18F]AV-1451 clustering of entorhinal and cortical uptake in Alzheimer's disease

Whitwell, J. L., Graff-Radford, J., Tosakulwong, N., Weigand, S. D., Machulda, M., Senjem, M. L., Schwarz, C. G., Spychalla, A. J., Jones, D. T., Drubach, D. A., Knopman, D. S., Boeve, B. F., Ertekin-Taner, N., Petersen, R. C., Lowe, V. J., Jack, C. R. & Josephs, K. A., Feb 1 2018, In : Annals of neurology. 83, 2, p. 248-257 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

[ 18 F]AV-1451 tau-PET and primary progressive aphasia

Josephs, K. A., Martin, P. R., Botha, H., Schwarz, C. G., Duffy, J. R., Clark, H. M., Machulda, M. M., Graff-Radford, J., Weigand, S. D., Senjem, M. L., Utianski, R. L., Drubach, D. A., Boeve, B. F., Jones, D. T., Knopman, D. S., Petersen, R. C., Jack, C. R., Lowe, V. J. & Whitwell, J. L., Mar 2018, In : Annals of neurology. 83, 3, p. 599-611 13 p.

Research output: Contribution to journalArticle

22 Scopus citations

[18F]AV-1451 tau positron emission tomography in progressive supranuclear palsy

Whitwell, J. L., Lowe, V. J., Tosakulwong, N., Weigand, S. D., Senjem, M. L., Schwarz, C. G., Spychalla, A. J., Petersen, R. C., Jack, C. R. & Josephs, K. A., Jan 1 2017, In : Movement Disorders. 32, 1, p. 124-133 10 p.

Research output: Contribution to journalArticle

74 Scopus citations
8 Scopus citations
5 Scopus citations

18F-FDG PET-CT pattern in idiopathic normal pressure hydrocephalus

Townley, R. A., Botha, H., Graff-Radford, J., Boeve, B. F., Petersen, R. C., Senjem, M. L., Knopman, D. S., Lowe, V., Jack, C. R. & Jones, D. T., 2018, In : NeuroImage: Clinical. 18, p. 897-902 6 p.

Research output: Contribution to journalArticle

10 Scopus citations

18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal persons

Knopman, D. S., Jack, C. R., Wiste, H. J., Lundt, E. S., Weigand, S. D., Vemuri, P., Lowe, V. J., Kantarci, K., Gunter, J. L., Senjem, M. L., Mielke, M. M., Roberts, R. O., Boeve, B. F. & Petersen, R. C., Sep 2014, In : Neurobiology of aging. 35, 9, p. 2096-2106 11 p.

Research output: Contribution to journalArticle

67 Scopus citations

1 H-MRS metabolites and rate of β-amyloid accumulation on serial PET in clinically normal adults

Nedelska, Z., Przybelski, S. A., Lesnick, T. G., Schwarz, C. G., Lowe, V. J., Machulda, M. M., Kremers, W. K., Mielke, M. M., Roberts, R. O., Boeve, B. F., Knopman, D. S., Petersen, R. C., Jack, C. R. & Kantarci, K., Sep 26 2017, In : Neurology. 89, 13, p. 1391-1399 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

2014 Update of the Alzheimer's Disease Neuroimaging Initiative: A review of papers published since its inception

Alzheimer's Disease Neuroimaging Initiative, Jun 1 2015, In : Alzheimer's and Dementia. 11, 6, p. e1-e120

Research output: Contribution to journalArticle

154 Scopus citations

3D tract-specific local and global analysis of white matter integrity in Alzheimer's disease

Alzheimer's Disease Neuroimaging Initiative, Mar 1 2017, In : Human Brain Mapping. 38, 3, p. 1191-1207 17 p.

Research output: Contribution to journalArticle

21 Scopus citations

A blood-based signature of cerebrospinal fluid Aβ 1–42 status

Alzheimer’s Disease Metabolomics Consortium & Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 4163.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Accelerated vs. unaccelerated serial MRI based TBM-SyN measurements for clinical trials in Alzheimer's disease

Alzheimer's Disease Neuroimaging Initiative, Jun 1 2015, In : NeuroImage. 113, p. 61-69 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

A commonly carried genetic variant in the delta opioid receptor gene, OPRD1, is associated with smaller regional brain volumes: Replication in elderly and young populations

Roussotte, F. F., Jahanshad, N., Hibar, D. P., Sowell, E. R., Kohannim, O., Barysheva, M., Hansell, N. K., Mcmahon, K. L., de Zubicaray, G. I., Montgomery, G. W., Martin, N. G., Wright, M. J., Toga, A. W., Jack, C. R., Weiner, M. W. & Thompson, P. M., Apr 2014, In : Human Brain Mapping. 35, 4, p. 1226-1236 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

A comparison of manual tracing and FreeSurfer for estimating hippocampal volume over the adult lifespan

Schmidt, M. F., Storrs, J. M., Freeman, K. B., Jack, C. R., Turner, S. T., Griswold, M. E. & Mosley, T. H., Jun 2018, In : Human Brain Mapping. 39, 6, p. 2500-2513 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

A Comparison of Partial Volume Correction Techniques for Measuring Change in Serial Amyloid PET SUVR

Schwarz, C. G., Gunter, J. L., Lowe, V. J., Weigand, S., Vemuri, P., Senjem, M. L., Petersen, R. C., Knopman, D. S. & Jack, C. R., 2019, In : Journal of Alzheimer's Disease. 67, 1, p. 181-195 15 p.

Research output: Contribution to journalArticle

7 Scopus citations
16 Scopus citations

Adapting a PET Imaging Agent for Correlative Microscopy of Meningiomas and Other Intracranial Tumors

Lingle, W. L., Negron, V., Johnson, G. B., Nathan, M. A., Parasi, J. E., Johnson, A. J., Hunt, C. H., Peller, P. J., Broski, S. M., Fauq, A. H., Jack, C. R., Petersen, R. C., Klunk, W. E., Mathis, C. A. & Lowe, V., 2012, In : Microscopy and Microanalysis. 18, p. 178-179 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Age, sex, and APOE ϵ4 effects on memory, brain structure, and β-Amyloid across the adult life Span

Jack, C. R., Wiste, H. J., Weigand, S. D., Knopman, D. S., Vemuri, P., Mielke, M. M., Lowe, V., Senjem, M. L., Gunter, J. L., Machulda, M. M., Gregg, B. E., Pankratz, V. S., Rocca, W. A. & Petersen, R. C., May 2015, In : JAMA neurology. 72, 5, p. 511-519 9 p.

Research output: Contribution to journalArticle

159 Scopus citations

Age, vascular health, and Alzheimer disease biomarkers in an elderly sample

Vemuri, P., Lesnick, T. G., Przybelski, S. A., Knopman, D. S., Lowe, V. J., Graff-Radford, J., Roberts, R. O., Mielke, M. M., Machulda, M. M., Petersen, R. C. & Jack, C. R., Nov 2017, In : Annals of neurology. 82, 5, p. 706-718 13 p.

Research output: Contribution to journalArticle

58 Scopus citations

Age and neurodegeneration imaging biomarkers in persons with Alzheimer disease dementia

Knopman, D. S., Jack, C. R., Wiste, H. J., Weigand, S. D., Vemuri, P., Lowe, V. J., Kantarci, K., Gunter, J. L., Senjem, M. L., Mielke, M. M., Machulda, M. M., Roberts, R. O., Boeve, B. F., Jones, D. T. & Petersen, R. C., Aug 16 2016, In : Neurology. 87, 7, p. 691-698 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

Age-related changes in the default mode network are more advanced in Alzheimer disease

Jones, D. T., MacHulda, M. M., Vemuri, P., McDade, E. M., Zeng, G., Senjem, M. L., Gunter, J. L., Przybelski, S. A., Avula, R. T., Knopman, D. S., Boeve, B. F., Petersen, R. C. & Jack, C. R., Oct 18 2011, In : Neurology. 77, 16, p. 1524-1531 8 p.

Research output: Contribution to journalArticle

203 Scopus citations
113 Scopus citations

Age-specific population frequencies of cerebral β-amyloidosis and neurodegeneration among people with normal cognitive function aged 50-89 years: A cross-sectional study

Jack, C. R., Wiste, H. J., Weigand, S. D., Rocca, W. A., Knopman, D. S., Mielke, M. M., Lowe, V. J., Senjem, M. L., Gunter, J. L., Preboske, G. M., Pankratz, V. S., Vemuri, P. & Petersen, R. C., Oct 1 2014, In : The Lancet Neurology. 13, 10, p. 997-1005 9 p.

Research output: Contribution to journalArticle

204 Scopus citations

A large-scale comparison of cortical thickness and volume methods for measuring Alzheimer's disease severity

Schwarz, C. G., Gunter, J. L., Wiste, H. J., Przybelski, S. A., Weigand, S. D., Ward, C. P., Senjem, M. L., Vemuri, P., Murray, M. E., Dickson, D. W., Parisi, J. E., Kantarci, K., Weiner, M. W., Petersen, R. C. & Jack, C. R., 2016, In : NeuroImage: Clinical. 11, p. 802-812 11 p.

Research output: Contribution to journalArticle

74 Scopus citations

Alliance for Aging Research AD Biomarkers Work Group: Structural MRI

Jack, C. R., Dec 2011, In : Neurobiology of aging. 32, SUPPL. 1, p. S48-S57

Research output: Contribution to journalArticle

36 Scopus citations

Altered functional connectivity in asymptomatic MAPT subjects A comparison to bvFTD

Whitwell, J. L., Josephs, K. A., Avula, R., Tosakulwong, N., Weigand, S. D., Senjem, M. L., Vemuri, P., Jones, D. T., Gunter, J. L., Baker, M., Wszolek, Z. K., Knopman, D. S., Rademakers, R., Petersen, R. C., Boeve, B. F. & Jack, C. R., Aug 30 2011, In : Neurology. 77, 9, p. 866-874 9 p.

Research output: Contribution to journalArticle

88 Scopus citations

Altered functional MR imaging language activation in elderly individuals with cerebral leukoaraiosis

Welker, K. M., De Jesus, R. O., Watson, R. E., Machulda, M. M. & Jack, C. R., Oct 1 2012, In : Radiology. 265, 1, p. 222-232 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Alzheimer's disease: The next frontier—Special Report 2017

Karlawish, J., Jack, C. R., Rocca, W. A., Snyder, H. M. & Carrillo, M. C., Apr 1 2017, In : Alzheimer's and Dementia. 13, 4, p. 374-380 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Amyloid, Vascular, and Resilience Pathways Associated with Cognitive Aging

Vemuri, P., Lesnick, T. G., Knopman, D. S., Przybelski, S. A., Reid, R. I., Mielke, M. M., Graff-Radford, J., Lowe, V. J., Machulda, M. M., Petersen, R. C. & Jack, C. R., Dec 1 2019, In : Annals of neurology. 86, 6, p. 866-877 12 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease

Dominantly Inherited Alzheimer Network (DIAN) & PREVENT-AD Research Group, 2020, (Accepted/In press) In : Biological psychiatry.

Research output: Contribution to journalArticle

1 Scopus citations

Amyloid- and tau-PET imaging in a familial prion kindred

Jones, D. T., Townley, R. A., Graff-Radford, J., Botha, H., Knopman, D. S., Petersen, R. C., Jack, C. R., Lowe, V. J. & Boeve, B. F., Dec 1 2018, In : Neurology: Genetics. 4, 6, e290.

Research output: Contribution to journalArticle

1 Scopus citations

Amyloid burden correlates with cognitive decline in Alzheimer's disease presenting with aphasia

Jung, Y., Whitwell, J. L., Duffy, J. R., Strand, E. A., Machulda, M. M., Senjem, M. L., Lowe, V., Jack, C. R. & Josephs, K. A., Jul 2014, In : European Journal of Neurology. 21, 7, p. 1040-1043 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Amyloid pathway-based candidate gene analysis of [ 11 C]PiB-PET in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort

Swaminathan, S., Shen, L., Risacher, S. L., Yoder, K. K., West, J. D., Kim, S., Nho, K., Foroud, T., Inlow, M., Potkin, S. G., Huentelman, M. J., Craig, D. W., Jagust, W. J., Koeppe, R. A., Mathis, C. A., Jack, C. R., Weiner, M. W. & Saykin, A. J., Mar 2012, In : Brain Imaging and Behavior. 6, 1, p. 1-15 15 p.

Research output: Contribution to journalArticle

30 Scopus citations

Amyloid-related imaging abnormalities-haemosiderin (ARIA-H) in patients with Alzheimer's disease treated with bapineuzumab: A historical, prospective secondary analysis

Arrighi, H. M., Barakos, J., Barkhof, F., Tampieri, D., Jack, C., Melançon, D., Morris, K., Ketter, N., Liu, E. & Brashear, H. R., Jan 1 2016, In : Journal of Neurology, Neurosurgery and Psychiatry. 87, 1, p. 106-112 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer's Association Research Roundtable Workgroup

Sperling, R. A., Jack, C. R., Black, S. E., Frosch, M. P., Greenberg, S. M., Hyman, B. T., Scheltens, P., Carrillo, M. C., Thies, W., Bednar, M. M., Black, R. S., Brashear, H. R., Grundman, M., Siemers, E. R., Feldman, H. H. & Schindler, R. J., Jul 2011, In : Alzheimer's and Dementia. 7, 4, p. 367-385 19 p.

Research output: Contribution to journalArticle

286 Scopus citations

Amyloid-β — a reflection of risk or a preclinical marker?

Jack, C. R. J. & Vemuri, P. D., Apr 30 2018, (Accepted/In press) In : Nature Reviews Neurology. p. 1-2 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Amyloid-β deposition and regional grey matter atrophy rates in dementia with Lewy bodies

Sarro, L., Senjem, M. L., Lundt, E. S., Przybelski, S. A., Lesnick, T. G., Graff-Radford, J., Boeve, B. F., Lowe, V. J., Ferman, T. J., Knopman, D. S., Comi, G., Filippi, M., Petersen, R. C., Jack, C. R. & Kantarci, K., Oct 1 2016, In : Brain. 139, 10, p. 2740-2750 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

An atlas of cortical circular RNA expression in Alzheimer disease brains demonstrates clinical and pathological associations

the Dominantly Inherited Alzheimer Network (DIAN), Nov 1 2019, In : Nature Neuroscience. 22, 11, p. 1903-1912 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
207 Scopus citations

An Evaluation of the Progressive Supranuclear Palsy Speech/Language Variant

Whitwell, J. L., Stevens, C. A., Duffy, J. R., Clark, H. M., Machulda, M. M., Strand, E. A., Martin, P. R., Utianski, R. L., Botha, H., Spychalla, A. J., Senjem, M. L., Schwarz, C. G., Jack, C. R., Ali, F., Hassan, A. & Josephs, K. A., Jul 2019, In : Movement Disorders Clinical Practice. 6, 6, p. 452-461 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

An investigation of cerebrovascular lesions in dementia with Lewy bodies compared to Alzheimer's disease

Sarro, L., Tosakulwong, N., Schwarz, C. G., Graff-Radford, J., Przybelski, S. A., Lesnick, T. G., Zuk, S. M., Reid, R. I., Raman, M. R., Boeve, B. F., Ferman, T. J., Knopman, D. S., Comi, G., Filippi, M., Murray, M. E., Parisi, J. E., Dickson, D. W., Petersen, R. C., Jack, C. R. & Kantarci, K., Mar 1 2017, In : Alzheimer's and Dementia. 13, 3, p. 257-266 10 p.

Research output: Contribution to journalArticle

16 Scopus citations
2 Scopus citations

An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer disease

Jack, C. R., Knopman, D. S., Weigand, S. D., Wiste, H. J., Vemuri, P., Lowe, V., Kantarci, K., Gunter, J. L., Senjem, M. L., Ivnik, R. J., Roberts, R. O., Rocca, W. A., Boeve, B. F. & Petersen, R. C., Jun 2012, In : Annals of neurology. 71, 6, p. 765-775 11 p.

Research output: Contribution to journalArticle

397 Scopus citations

A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer’s Disease Data

The Alzheimer’s Disease Neuroimaging Initiative, Dec 1 2019, In : Scientific reports. 9, 1, 19589.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Ante mortem amyloid imaging and β-amyloid pathology in a case with dementia with Lewy bodies

Kantarci, K., Yang, C., Schneider, J. A., Senjem, M. L., Reyes, D. A., Lowe, V. J., Barnes, L. L., Aggarwal, N. T., Bennett, D. A., Smith, G. E., Petersen, R. C., Jack, C. R. & Boeve, B. F., May 2012, In : Neurobiology of aging. 33, 5, p. 878-885 8 p.

Research output: Contribution to journalArticle

54 Scopus citations

Antemortem differential diagnosis of dementia pathology using structural MRI: Differential-STAND

Vemuri, P., Simon, G., Kantarci, K., Whitwell, J. L., Senjem, M. L., Przybelski, S. A., Gunter, J. L., Josephs, K. A., Knopman, D. S., Boeve, B. F., Ferman, T. J., Dickson, D. W., Parisi, J. E., Petersen, R. C. & Jack, C. R., Mar 15 2011, In : NeuroImage. 55, 2, p. 522-531 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

Antemortem MRI findings associated with microinfarcts at autopsy

Raman, M. R., Preboske, G. M., Przybelski, S. A., Gunter, J. L., Senjem, M. L., Vemuri, P., Murphy, M. C., Murray, M. E., Boeve, B. F., Knopman, D. S., Petersen, R. C., Parisi, J. E., Dickson, D. W., Jack, C. R. & Kantarci, K., Jun 3 2014, In : Neurology. 82, 22, p. 1951-1958 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Antemortem volume loss mirrors TDP-43 staging in older adults with non-frontotemporal lobar degeneration

Bejanin, A., Murray, M. E., Martin, P., Botha, H., Tosakulwong, N., Schwarz, C. G., Senjem, M. L., Chételat, G., Kantarci, K., Jack, C. R., Boeve, B. F., Knopman, D. S., Petersen, R. C., Giannini, C., Parisi, J. E., Dickson, D. W., Whitwell, J. L. & Josephs, K. A., Nov 1 2019, In : Brain. 142, 11, p. 3621-3635 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

Aortic hemodynamics and white matter hyperintensities in normotensive postmenopausal women

Barnes, J. N., Harvey, R. E., Zuk, S. M., Lundt, E. S., Lesnick, T. G., Gunter, J. L., Senjem, M. L., Shuster, L. T., Miller, V. M., Jack, C. R., Joyner, M. J. & Kantarci, K., May 1 2017, In : Journal of Neurology. 264, 5, p. 938-945 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Aortic Stiffness and White Matter Microstructural Integrity Assessed by Diffusion Tensor Imaging: The ARIC-NCS

Wei, J., Palta, P., Meyer, M. L., Kucharska-Newton, A., Pence, B. W., Aiello, A. E., Power, M. C., Walker, K. A., Sharrett, A. R., Tanaka, H., Jack, C. R., Mosley, T. H., Reid, R. I., Reyes, D. A. & Heiss, G., Mar 17 2020, In : Journal of the American Heart Association. 9, 6, p. e014868

Research output: Contribution to journalArticle

Open Access