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  • Ayalew Tefferi
2020

Aetiology and outcomes of secondary myelofibrosis occurring in the context of inherited platelet disorders: A single institutional study of four patients

Saliba, A. N., Ferrer, A., Gangat, N., Pruthi, R. K., Tefferi, A., Higgins, A., Bezerra, E. D., Buglioni, A., Salama, M. E., Klee, E. W., Pinto e Vairo, F., Mangaonkar, A., Majerus, J., Chen, D. & Patnaik, M. M., 2020, (Accepted/In press) In : British journal of haematology.

Research output: Contribution to journalLetter

Open Access

A population-based study of chronic neutrophilic leukemia in the United States

Ruan, G. J., Smith, C. J., Day, C., Harmsen, W. S., Zblewski, D. L., Alkhateeb, H., Begna, K., Al-Kali, A., Litzow, M. R., Hogan, W., Szuber, N., Gangat, N., Patnaik, M. S., Pardanani, A., Elliott, M. A., Tefferi, A., Go, R. S. & Shah, M. V., Jun 1 2020, In : Blood cancer journal. 10, 6, 68.

Research output: Contribution to journalLetter

Open Access
Open Access
5 Scopus citations

Chronic neutrophilic leukemia: 2020 update on diagnosis, molecular genetics, prognosis, and management

Szuber, N., Elliott, M. & Tefferi, A., Feb 1 2020, In : American journal of hematology. 95, 2, p. 212-224 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Clinical, molecular, and prognostic correlates of number, type, and functional localization of TET2 mutations in chronic myelomonocytic leukemia (CMML)—a study of 1084 patients

Coltro, G., Mangaonkar, A. A., Lasho, T. L., Finke, C. M., Pophali, P., Carr, R., Gangat, N., Binder, M., Pardanani, A., Fernandez-Zapico, M., Robertson, K. D., Bosi, A., Droin, N., Vannucchi, A. M., Tefferi, A., Hunter, A., Padron, E., Solary, E. & Patnaik, M. M., May 1 2020, In : Leukemia. 34, 5, p. 1407-1421 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

Clinical utility of fluorescence in situ hybridization-based diagnosis of BCR-ABL1 like (Philadelphia chromosome like) B-acute lymphoblastic leukemia

Anagnostou, T., Knudson, R. A., Pearce, K. E., Meyer, R. G., Pitel, B. A., Peterson, J. F., Baughn, L. B., Reichard, K. K., Ketterling, R. P., Kloft-Nelson, S. M., Knutson, D. L., Khan, S. P., Gangat, N., Litzow, M. R., Hogan, W. J., Wolanskyj, A., Al-Kali, A., Begna, K. H., Elliott, M., Pardanani, A. & 8 others, Foran, J., Shah, M., Tefferi, A., Alkhateeb, H., Halling, K. C., Rodriguez, V., Greipp, P. T. & Patnaik, M. M., Mar 1 2020, In : American journal of hematology. 95, 3, p. E68-E72

Research output: Contribution to journalLetter

Open Access
Open Access

Cutaneous blastic plasmacytoid dendritic cell neoplasm arising in the context of TET2 and ZRSR2 mutated clonal cytopenias of unknown significance, secondary to somatic copy number losses involving CDK2NA/2NB and MTAP

Li, M., Shah, M., Binder, M., Lasho, T., Carr, R., Mangaonkar, A., Gangat, N., Coltro, G., Tefferi, A., Dao, L., Peters, M., Chiu, A. & Patnaik, M. M., Feb 1 2020, In : American journal of hematology. 95, 2, p. E31-E34

Research output: Contribution to journalLetter

Open Access

Early post-transplantation factors predict survival outcomes in patients undergoing allogeneic hematopoietic cell transplantation for myelofibrosis

Jain, T., Kunze, K. L., Mountjoy, L., Partain, D. K., Kosiorek, H., Khera, N., Hogan, W. J., Roy, V., Slack, J. L., Noel, P., Fauble, V. D-S., Leis, J. F., Sproat, L., Tefferi, A., Patnaik, M. M., Mesa, R. A. & Palmer, J., Mar 1 2020, In : Blood cancer journal. 10, 3, 36.

Research output: Contribution to journalArticle

Open Access

Essential thrombocythemia

Fleischman, R. A., Rumi, E., Cazzola, M., Tefferi, A. & Pardanani, A., Mar 19 2020, In : New England Journal of Medicine. 382, 12

Research output: Contribution to journalLetter

Essential Thrombocythemia. Reply

Tefferi, A. & Pardanani, A., Mar 19 2020, In : The New England journal of medicine. 382, 12, p. e21

Research output: Contribution to journalLetter

Essential Thrombocythemia. Reply

Tefferi, A. & Pardanani, A., Mar 19 2020, In : The New England journal of medicine. 382, 12, p. e21

Research output: Contribution to journalLetter

Landscape of RAS pathway mutations in patients with myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes: a study of 461 molecularly annotated patients

Buradkar, A., Bezerra, E., Coltro, G., Lasho, T. L., Finke, C. M., Gangat, N., Carr, R. M., Binder, M., Mangaonkar, A. A., Ketterling, R., Khan, S., Rodriguez, V., Tefferi, A. & Patnaik, M. M., 2020, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Mutation-enhanced international prognostic systems for essential thrombocythaemia and polycythaemia vera

Tefferi, A., Guglielmelli, P., Lasho, T. L., Coltro, G., Finke, C. M., Loscocco, G. G., Sordi, B., Szuber, N., Rotunno, G., Pacilli, A., Hanson, C. A., Ketterling, R. P., Pardanani, A., Gangat, N. & Vannucchi, A. M., Apr 1 2020, In : British journal of haematology. 189, 2, p. 291-302 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Myelofibrosis biology and contemporary management

Gangat, N. & Tefferi, A., Jan 1 2020, (Accepted/In press) In : British journal of haematology.

Research output: Contribution to journalReview article

1 Scopus citations

Phenotypic correlates and prognostic outcomes of TET2 mutations in myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes: A comprehensive study of 504 adult patients

Coltro, G., Antelo, G., Lasho, T. L., Finke, C. M., Pardanani, A., Gangat, N., Carr, R. M., Binder, M., Mangaonkar, A. A., Ketterling, R., Fernandez-Zapico, M. E., Robertson, K. D., Bosi, A., Vannucchi, A. M., Tefferi, A. & Patnaik, M. M., Jan 1 2020, (Accepted/In press) In : American journal of hematology.

Research output: Contribution to journalLetter

Open Access

Pregnancy outcomes in myeloproliferative neoplasms: A Mayo Clinic report on 102 pregnancies

Gangat, N., Joshi, M., Shah, S., Yogarajah, M., Patnaik, M. M., Pardanani, A., Wolanskyj-Spinner, A. P. & Tefferi, A., May 1 2020, In : American journal of hematology. 95, 5, p. E114-E117

Research output: Contribution to journalLetter

Open Access

Response to erythropoiesis-stimulating agents in patients with WHO-defined myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN-RS-T)

Antelo, G., Mangaonkar, A. A., Coltro, G., Buradkar, A., Lasho, T. L., Finke, C., Carr, R., Binder, M., Gangat, N., Al-Kali, A., Elliott, M. A., King, R. L., Howard, M., Melody, M. E., Hogan, W., Litzow, M. R., Tefferi, A., Fernandez-Zapico, M. E., Komrokji, R. & Patnaik, M. M., Jan 1 2020, (Accepted/In press) In : British journal of haematology.

Research output: Contribution to journalLetter

Open Access

Special considerations in the management of patients with myelodysplastic myndrome / myeloproliferative neoplasm overlap syndromes during the SARS-CoV-2 pandemic

Patnaik, M. M., Lasho, T., Padron, E., McCullough, K., Al-kali, A., Tefferi, A., Zeidan, A. M., Gangat, N., Savona, M., Steensma, D. P. & Solary, E., Aug 1 2020, In : American journal of hematology. 95, 8, p. E203-E208

Research output: Contribution to journalLetter

Open Access
1 Scopus citations

Spectrum of abnormalities and clonal transformation in germline RUNX1 familial platelet disorder and a genomic comparative analysis with somatic RUNX1 mutations in MDS/MPN overlap neoplasms

DiFilippo, E. C., Coltro, G., Carr, R. M., Mangaonkar, A. A., Binder, M., Khan, S. P., Rodriguez, V., Gangat, N., Wolanskyj, A., Pruthi, R. K., Chen, D., He, R., Viswanatha, D. S., Lasho, T., Finke, C., Tefferi, A., Pardanani, A. & Patnaik, M. M., 2020, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalLetter

Splanchnic vein thromboses associated with myeloproliferative neoplasms: An international, retrospective study on 518 cases

Sant'Antonio, E., Guglielmelli, P., Pieri, L., Primignani, M., Randi, M. L., Santarossa, C., Rumi, E., Cervantes, F., Delaini, F., Carobbio, A., Betti, S., Rossi, E., Lavi, N., Harrison, C. N., Curto-Garcia, N., Gisslinger, H., Gisslinger, B., Specchia, G., Ricco, A., Vianelli, N. & 15 others, Polverelli, N., Koren-Michowitz, M., Ruggeri, M., Girodon, F., Ellis, M., Iurlo, A., Mannelli, F., Mannelli, L., Sordi, B., Loscocco, G. G., Cazzola, M., De Stefano, V., Barbui, T., Tefferi, A. & Vannucchi, A. M., Feb 1 2020, In : American journal of hematology. 95, 2, p. 156-166 11 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

The new WHO classification for essential thrombocythemia calls for revision of available evidences

Barbui, T., Thiele, J., Ferrari, A., Vannucchi, A. M. & Tefferi, A., Feb 1 2020, In : Blood cancer journal. 10, 2, 22.

Research output: Contribution to journalReview article

Open Access

WHO defined chronic eosinophilic leukemia, not otherwise specified (CEL, NOS): A contemporary series from the Mayo Clinic

Morsia, E., Reichard, K., Pardanani, A., Tefferi, A. & Gangat, N., Jul 1 2020, In : American journal of hematology. 95, 7, p. E172-E174

Research output: Contribution to journalLetter

Open Access
1 Scopus citations
2019

3023 Mayo Clinic Patients With Myeloproliferative Neoplasms: Risk-Stratified Comparison of Survival and Outcomes Data Among Disease Subgroups

Szuber, N., Mudireddy, M., Nicolosi, M., Penna, D., Vallapureddy, R. R., Lasho, T. L., Finke, C., Begna, K., Elliott, M. A., Hook, C. C., Wolanskyj, A. P., Patnaik, M. M., Hanson, C. A., Ketterling, R. P., Sirhan, S., Pardanani, A. D., Gangat, N., Busque, L. & Tefferi, A., Jan 1 2019, In : Mayo Clinic proceedings.

Research output: Contribution to journalArticle

9 Scopus citations

AKT activation is a feature of CALR mutant myeloproliferative neoplasms

Fu, C., Wen, Q. J., Marinaccio, C., Ling, T., Chen, W., Bulic, M., Lasho, T., Tefferi, A., Crispino, J. D. & Xu, K., Jan 1 2019, In : Leukemia. 33, 1, p. 271-274 4 p.

Research output: Contribution to journalArticle

A prospective evaluation of vitamin B1 (thiamine) level in myeloproliferative neoplasms: clinical correlations and impact of JAK2 inhibitor therapy

Gangat, N., Phelps, A., Lasho, T. L., Finke, C. M., Vallapureddy, R., Hanson, C. A., Ketterling, R. P., Patnaik, M. M., Pardanani, A. & Tefferi, A., Feb 1 2019, In : Blood Cancer Journal. 9, 2, 11.

Research output: Contribution to journalLetter

4 Scopus citations

Aurora kinase A inhibition provides clinical benefit, normalizes megakaryocytes, and reduces bone marrow fibrosis in patients with myelofibrosis: A phase I trial

Gangat, N., Marinaccio, C., Swords, R., Watts, J. M., Gurbuxani, S., Rademaker, A., Fought, A. J., Frankfurt, O., Altman, J. K., Wen, Q. J., Farnoud, N., Famulare, C. A., Patel, A., Tapia, R., Vallapureddy, R. R., Barath, S., Graf, A., Handlogten, A., Zblewski, D., Patnaik, M. M. & 14 others, Al-Kali, A., Dinh, Y. T., Prahl, K. E., Patel, S., Nobrega, J. C., Tejera, D., Thomassen, A., Gao, J., Ji, P., Rampal, R. K., Giles, F. J., Tefferi, A., Stein, B. & Crispino, J. D., Aug 15 2019, In : Clinical Cancer Research. 25, 16, p. 4898-4906 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Calculator-free point-of-care prognostication in myelodysplastic syndromes

Tefferi, A., Hanson, C. A., Ketterling, R. P., Pardanani, A. & Gangat, N., Jan 1 2019, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

Clinical correlates, prognostic impact and survival outcomes in chronic myelomonocytic leukemia patients with the JAK2V617F mutation

Patnaik, M. M., Pophali, P. A., Lasho, T. L., Finke, C. M., Horna, P., Ketterling, R. P., Gangat, N., Mangaonkar, A. A., Pardanani, A. & Tefferi, A., Jan 1 2019, In : Haematologica. 104, 6, p. e236-e239

Research output: Contribution to journalLetter

Open Access
6 Scopus citations

Comments on pre-fibrotic myelofibrosis and how should it be managed

Barbui, T., Thiele, J., Gisslinger, H., Orazi, A., Vannucchi, A. M., Gianelli, U., Beham-Schmid, C. & Tefferi, A., Jul 2019, In : British journal of haematology. 186, 2, p. 358-360 3 p.

Research output: Contribution to journalLetter

Open Access
2 Scopus citations

Cytogenetic clonal evolution in myeloproliferative neoplasms: contexts and prognostic impact among 648 patients with serial bone marrow biopsies

Tefferi, A., Nicolosi, M., Penna, D., Vallapureddy, R., Hanson, C. A., Pardanani, A. D., Gangat, N. & Ketterling, R. P., Jan 1 2019, In : Leukemia.

Research output: Contribution to journalLetter

Essential thrombocythemia

Tefferi, A. & Pardanani, A., Nov 28 2019, In : New England Journal of Medicine. 381, 22, p. 2135-2144 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Etiologies of Extreme Thrombocytosis: A Contemporary Series

Hsieh, R. W., Ravindran, A., Hook, C. C., Begna, K. H., Ashrani, A. A., Pruthi, R. K., Marshall, A. L., Hogan, W., Litzow, M., Hoyer, J., Oliveira, J. L., Vishnu, P., Call, T. G., Al-Kali, A., Patnaik, M., Gangat, N., Pardanani, A., Tefferi, A. & Go, R. S., Aug 1 2019, In : Mayo Clinic proceedings. 94, 8, p. 1542-1550 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Functional evaluation of isocitrate dehydrogenase 1 and 2 variants of unclear significance in chronic myeloid neoplasms

Tischer, A., Antelo, G., Coltro, G., Finke, C. M., Gonsalves, W., Pardanani, A., Ketterling, R., Mangaonkar, A., Gangat, N., Tefferi, A., Patnaik, M. M. & Lasho, T. L., Dec 2019, In : Leukemia Research. 87, 106264.

Research output: Contribution to journalLetter

Open Access
1 Scopus citations

Hybridization capture-based next generation sequencing reliably detects FLT3 mutations and classifies FLT3-internal tandem duplication allelic ratio in acute myeloid leukemia: a comparative study to standard fragment analysis

He, R., Devine, D. J., Tu, Z. J., Mai, M., Chen, D., Nguyen, P. L., Oliveira, J., Hoyer, J., Reichard, K. K., Ollila, P. L., Al-Kali, A., Tefferi, A., Begna, K., Patnaik, M. M., Alkhateeb, H. & Viswanatha, D. S., Jan 1 2019, (Accepted/In press) In : Modern Pathology.

Research output: Contribution to journalArticle

Leukemic transformation among 1306 patients with primary myelofibrosis: risk factors and development of a predictive model

Vallapureddy, R. R., Mudireddy, M., Penna, D., Lasho, T. L., Finke, C. M., Hanson, C. A., Ketterling, R. P., Begna, K. H., Gangat, N., Pardanani, A. & Tefferi, A., Feb 1 2019, In : Blood Cancer Journal. 9, 2, 12.

Research output: Contribution to journalArticle

10 Scopus citations

Outcome of Myelodysplastic Syndromes Over Time in the United States: A National Cancer Data Base Study From 2004-2013

Al-Kali, A., Zblewski, D., Foran, J. M., Patnaik, M. M., Larrabee, B. R., Gangat, N., Begna, K., Elliott, M. A., Hogan, W., Tefferi, A., Litzow, M. R. & Go, R. S., Aug 1 2019, In : Mayo Clinic proceedings. 94, 8, p. 1467-1474 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management

Tefferi, A. & Barbui, T., Jan 2019, In : American journal of hematology. 94, 1, p. 133-143 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

Practical limitations of monocyte subset repartitioning by multiparametric flow cytometry in chronic myelomonocytic leukemia

Pophali, P. A., Timm, M. M., Mangaonkar, A. A., Shi, M., Reichard, K., Tefferi, A., Pavelko, K., Villasboas Bisneto, J. J. C. ., Jevremovic, D. & Patnaik, M. M., Sep 1 2019, In : Blood cancer journal. 9, 9, 65.

Research output: Contribution to journalLetter

Open Access
3 Scopus citations
11 Scopus citations

Safety and tolerability of lurbinectedin (PM01183) in patients with acute myeloid leukemia and myelodysplastic syndrome

Benton, C. B., Chien, K. S., Tefferi, A., Rodriguez, J., Ravandi, F., Daver, N., Jabbour, E., Jain, N., Alvarado, Y., Kwari, M., Pierce, S., Maiti, A., Hornbaker, M., Santos, M. A., Martinez, S., Siguero, M., Zblewski, D., Al-Kali, A., Hogan, W. J., Kantarjian, H. & 2 others, Pardanani, A. & Garcia-Manero, G., Feb 1 2019, In : Hematological Oncology. 37, 1, p. 96-102 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Suboptimal response rates to hypomethylating agent therapy in chronic myelomonocytic leukemia; a single institutional study of 121 patients

Coston, T., Pophali, P., Vallapureddy, R., Lasho, T. L., Finke, C. M., Ketterling, R. P., Carr, R., Binder, M., Mangaonkar, A. A., Gangat, N., Al-Kali, A., Litzow, M. R., Zblewski, D., Pardanani, A. D., Tefferi, A. & Patnaik, M. M., Jan 1 2019, In : American journal of hematology.

Research output: Contribution to journalArticle

10 Scopus citations

Thrombocytosis and essential thrombocythemia

Barbui, T., Finazzi, G. & Tefferi, A., Jan 1 2019, Platelets. Elsevier, p. 863-876 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Thrombocytosis and essential thrombocythemia

Barbui, T., Finazzi, G. & Tefferi, A., Jan 1 2019, Platelets. Elsevier, p. 863-876 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

World Health Organization class-independent risk categorization in mastocytosis

Pardanani, A. D., Lasho, T. L., Reichard, K. K., Hanson, C. A. & Tefferi, A., Mar 1 2019, In : Blood cancer journal. 9, 3, 29.

Research output: Contribution to journalLetter

Open Access
2 Scopus citations
2018

20+ Years and alive with primary myelofibrosis: Phenotypic signature of very long-lived patients

Penna, D., Lasho, T. L., Finke, C. M., Vallapureddy, R. R., Hanson, C. A., Ketterling, R. P., Pardanani, A., Gangat, N. & Tefferi, A., Jan 1 2018, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

1 Scopus citations

A comparison of clinical and molecular characteristics of patients with systemic mastocytosis with chronic myelomonocytic leukemia to CMML alone

Patnaik, M. M., Rangit Vallapureddy, V., Lasho, T. L., Hoversten, K. P., Finke, C. M., Ketterling, R. P., Hanson, C. A., Gangat, N., Tefferi, A. & Pardanani, A., Aug 1 2018, In : Leukemia. 32, 8, p. 1850-1856 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
12 Scopus citations

A novel predictive model of outcome in acute myeloid leukemia without favorable karyotype based on treatment strategy, karyotype and FLT3-ITD mutational status

Begna, K. H., Ali, W., Gangat, N., Elliott, M. A., Al-Kali, A., Litzow, M. R., Hook, C. C., Wolanskyj, A. P., Hogan, W. J., Patnaik, M. M., Pardanani, A., Zblewski, D. L., Chen, D., He, R., Viswanatha, D., Hanson, C. A., Ketterling, R. P. & Tefferi, A., Jan 1 2018, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

1 Scopus citations