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  • Clifford R Jr. Jack
Article

Aortic hemodynamics and white matter hyperintensities in normotensive postmenopausal women

Barnes, J. N., Harvey, R. E., Zuk, S. M., Lundt, E. S., Lesnick, T. G., Gunter, J. L., Senjem, M. L., Shuster, L. T., Miller, V. M., Jack, C. R., Joyner, M. J. & Kantarci, K., May 1 2017, In : Journal of Neurology. 264, 5, p. 938-945 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Aortic Stiffness and White Matter Microstructural Integrity Assessed by Diffusion Tensor Imaging: The ARIC-NCS

Wei, J., Palta, P., Meyer, M. L., Kucharska-Newton, A., Pence, B. W., Aiello, A. E., Power, M. C., Walker, K. A., Sharrett, A. R., Tanaka, H., Jack, C. R., Mosley, T. H., Reid, R. I., Reyes, D. A. & Heiss, G., Mar 17 2020, In : Journal of the American Heart Association. 9, 6, p. e014868

Research output: Contribution to journalArticle

Open Access

A phase 3 trial of IV immunoglobulin for Alzheimer disease

Relkin, N. R., Thomas, R. G., Rissman, R. A., Brewer, J. B., Rafii, M. S., Van Dyck, C. H., Jack, C. R., Sano, M., Knopman, D. S., Raman, R., Szabo, P., Gelmont, D. M., Fritsch, S. & Aisen, P. S., May 2 2017, In : Neurology. 88, 18, p. 1768-1775 8 p.

Research output: Contribution to journalArticle

59 Scopus citations

ApoE4 effects on automated diagnostic classifiers for mild cognitive impairment and Alzheimer's disease

Apostolova, L. G., Hwang, K. S., Kohannim, O., Avila, D., Elashoff, D., Jack, C. R., Shaw, L., Trojanowski, J. Q., Weiner, M. W. & Thompson, P. M., 2014, In : NeuroImage: Clinical. 4, p. 461-472 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

APOE and BCHE as modulators of cerebral amyloid deposition: A florbetapir PET genome-wide association study

Ramanan, V. K., Risacher, S. L., Nho, K., Kim, S., Swaminathan, S., Shen, L., Foroud, T. M., Hakonarson, H., Huentelman, M. J., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Koeppe, R. A., Jagust, W. J., Weiner, M. W. & Saykin, A. J., Mar 2014, In : Molecular Psychiatry. 19, 3, p. 351-357 7 p.

Research output: Contribution to journalArticle

119 Scopus citations

APOE and cortical superficial siderosis in CAA: Meta-analysis and potential mechanisms

Charidimou, A., Zonneveld, H. I., Shams, S., Kantarci, K., Shoamanesh, A., Hilal, S., Yates, P. A., Boulouis, G., Na, H. K., Pasi, M., Biffi, A., Chai, Y. L., Chong, J. R., Wahlund, L. O., Clifford, J. R., Chen, C., Gurol, M. E., Goldstein, J. N., Na, D. L., Barkhof, F. & 4 others, Seo, S. W., Rosand, J., Greenberg, S. M. & Viswanathan, A., Jul 23 2019, In : Neurology. 93, 4, p. E358-E371

Research output: Contribution to journalArticle

5 Scopus citations

APOE effect on Alzheimer's disease biomarkers in older adults with significant memory concern

Risacher, S. L., Kim, S., Nho, K., Foroud, T., Shen, L., Petersen, R. C., Jack, C. R., Beckett, L. A., Aisen, P. S., Koeppe, R. A., Jagust, W. J., Shaw, L. M., Trojanowski, J. Q., Weiner, M. W., Saykin, A. J. & Alzheimer's Disease Neuroimaging Initiative (ADNI), D. N. I. ADNI., Dec 1 2015, In : Alzheimer's and Dementia. 11, 12, p. 1417-1429 13 p.

Research output: Contribution to journalArticle

82 Scopus citations

APOE modifies the association between Aβ load and cognition in cognitively normal older adults

Kantarci, K., Lowe, V., Przybelski, S. A., Weigand, S. D., Senjem, M. L., Ivnik, R. J., Preboske, G. M., Roberts, R., Geda, Y. E., Boeve, B. F., Knopman, D. S., Petersen, R. C. & Jack, C. R., Jan 24 2012, In : Neurology. 78, 4, p. 232-240 9 p.

Research output: Contribution to journalArticle

120 Scopus citations

APOE ε4 influences β-amyloid deposition in primary progressive aphasia and speech apraxia

Josephs, K. A., Duffy, J. R., Strand, E. A., MacHulda, M. M., Senjem, M. L., Lowe, V. J., Jack, C. R. & Whitwell, J. L., Nov 1 2014, In : Alzheimer's and Dementia. 10, 6, p. 630-636 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Application of the national institute on aging-alzheimer's association AD criteria to ADNI

Lowe, V. J., Peller, P. J., Weigand, S. D., Quintero, C. M., Tosakulwong, N., Vemuri, P., Senjem, M. L., Jordan, L., Jack, C. R., Knopman, D. & Petersen, R. C., Jun 4 2013, In : Neurology. 80, 23, p. 2130-2137 8 p.

Research output: Contribution to journalArticle

35 Scopus citations
48 Scopus citations
13 Scopus citations

A single nucleotide polymorphism associated with reduced alcohol intake in the RASGRF2 gene predicts larger cortical volumes but faster longitudinal ventricular expansion in the elderly

Roussotte, F. F., Gutman, B. A., Hibar, D. P., Jahanshad, N., Madsen, S. K., Jack, C. R., Weiner, M. W. & Thompson, P. M., 2013, In : Frontiers in Aging Neuroscience. 5, DEC, Article 93.

Research output: Contribution to journalArticle

6 Scopus citations

A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer’s disease

The Dominantly Inherited Alzheimer Network, Mar 1 2020, In : Nature Medicine. 26, 3, p. 398-407 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Assessing atrophy measurement techniques in dementia: Results from the MIRIAD atrophy challenge

Cash, D. M., Frost, C., Iheme, L. O., Ünay, D., Kandemir, M., Fripp, J., Salvado, O., Bourgeat, P., Reuter, M., Fischl, B., Lorenzi, M., Frisoni, G. B., Pennec, X., Pierson, R. K., Gunter, J. L., Senjem, M. L., Jack, C. R., Guizard, N., Fonov, V. S., Collins, D. L. & 10 others, Modat, M., Cardoso, M. J., Leung, K. K., Wang, H., Das, S. R., Yushkevich, P. A., Malone, I. B., Fox, N. C., Schott, J. M. & Ourselin, S., Dec 1 2015, In : NeuroImage. 123, p. 149-164 16 p.

Research output: Contribution to journalArticle

34 Scopus citations

Association analysis of rare variants near the APOE region with CSF and neuroimaging biomarkers of Alzheimer’s disease

Nho, K., Kim, S., Horgusluoglu, E., Risacher, S. L., Shen, L., Kim, D., Lee, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Weiner, M. W., Green, R. C., Toga, A. W. & Saykin, A. J., May 24 2017, In : BMC medical genomics. 10, 29.

Research output: Contribution to journalArticle

9 Scopus citations

Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults

Alzheimer's Disease Neuroimaging Initiative, Jun 2016, In : JAMA neurology. 73, 6, p. 721-732 12 p.

Research output: Contribution to journalArticle

109 Scopus citations

Association Between Functional Performance and Alzheimer's Disease Biomarkers in Individuals Without Dementia

Vassilaki, M., Aakre, J. A., Kremers, W. K., Mielke, M. M., Geda, Y. E., Machulda, M. M., Knopman, D. S., Coloma, P. M., Schauble, B., Vemuri, P., Lowe, V. J., Jack, C. R., Petersen, R. C. & Roberts, R. O., Dec 2018, In : Journal of the American Geriatrics Society. 66, 12, p. 2274-2281 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Association between microinfarcts and blood pressure trajectories

Graff-Radford, J., Raman, M. R., Rabinstein, A. A., Przybelski, S. A., Lesnick, T. G., Boeve, B. F., Murray, M. E., Dickson, D. W., Ross Reichard, R., Parisi, J. E., Knopman, D. S., Petersen, R. C., Jack, C. R. & Kantarci, K., Feb 2018, In : JAMA neurology. 75, 2, p. 212-218 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Association between white matter hyperintensities, cortical volumes, and late-onset epilepsy

Johnson, E. L., Krauss, G. L., Lee, A. K., Schneider, A. L. C., Kucharska-Newton, A. M., Huang, J., Jack, C. R. & Gottesman, R. F., Feb 26 2019, In : Neurology. 92, 9, p. E988-E995

Research output: Contribution to journalArticle

1 Scopus citations

Association of Alzheimer's disease GWAS loci with MRI markers of brain aging

Chauhan, G., Adams, H. H. H., Bis, J. C., Weinstein, G., Yu, L., Töglhofer, A. M., Smith, A. V., van der Lee, S. J., Gottesman, R. F., Thomson, R., Wang, J., Yang, Q., Niessen, W. J., Lopez, O. L., Becker, J. T., Phan, T. G., Beare, R. J., Arfanakis, K., Fleischman, D., Vernooij, M. W. & 19 others, Mazoyer, B., Schmidt, H., Srikanth, V., Knopman, D. S., Jack, C. R., Amouyel, P., Hofman, A., DeCarli, C., Tzourio, C., van Duijn, C. M., Bennett, D. A., Schmidt, R., Longstreth, W. T., Mosley, T. H., Fornage, M., Launer, L. J., Seshadri, S., Ikram, M. A. & Debette, S., Apr 1 2015, In : Neurobiology of aging. 36, 4, p. 1765.e7-1765.e16

Research output: Contribution to journalArticle

46 Scopus citations
Open Access
2 Scopus citations

Association of Atrial Fibrillation With White Matter Disease: The ARIC Study

Shao, I. Y., Power, M. C., Mosley, T., Jack, C., Gottesman, R. F., Chen, L. Y., Norby, F. L., Soliman, E. Z. & Alonso, A., Apr 1 2019, In : Stroke. 50, 4, p. 989-991 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Association of Bilateral Salpingo-Oophorectomy before Menopause Onset with Medial Temporal Lobe Neurodegeneration

Zeydan, B., Tosakulwong, N., Schwarz, C. G., Senjem, M. L., Gunter, J. L., Reid, R. I., Gazzuola Rocca, L., Lesnick, T. G., Smith, C. Y., Bailey, K. R., Lowe, V. J., Roberts, R. O., Jack, C. R., Petersen, R. C., Miller, V. M., Mielke, M. M., Rocca, W. A. & Kantarci, K., Jan 2019, In : JAMA neurology. 76, 1, p. 95-100 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Association of brain amyloid-β with cerebral perfusion and structure in Alzheimer's disease and mild cognitive impairment

Mattsson, N., Tosun, D., Insel, P. S., Simonson, A., Jack, C. R., Beckett, L. A., Donohue, M., Jagust, W., Schuff, N. & Weiner, M. W., May 2014, In : Brain. 137, 5, p. 1550-1561 12 p.

Research output: Contribution to journalArticle

74 Scopus citations

Association of Brain Magnetic Resonance Imaging Signs With Cognitive Outcomes in Persons With Nonimpaired Cognition and Mild Cognitive Impairment

Wu, A., Sharrett, A. R., Gottesman, R. F., Power, M. C., Mosley, T. H., Jack, C. R., Knopman, D. S., Windham, B. G., Gross, A. L. & Coresh, J., May 3 2019, In : JAMA Network Open. 2, 5, p. e193359

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Association of Cerebrospinal Fluid Neurofilament Light Protein with Risk of Mild Cognitive Impairment among Individuals Without Cognitive Impairment

Kern, S., Syrjanen, J. A., Blennow, K., Zetterberg, H., Skoog, I., Waern, M., Hagen, C. E., Van Harten, A. C., Knopman, D. S., Jack, C. R., Petersen, R. C. & Mielke, M. M., Feb 2019, In : JAMA neurology. 76, 2, p. 187-193 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Association of elevated amyloid levels with cognition and biomarkers in cognitively normal people from the community

Petersen, R. C., Wiste, H. J., Weigand, S. D., Rocca, W. A., Roberts, R. O., Mielke, M. M., Lowe, V. J., Knopman, D. S., Pankratz, V. S., Machulda, M. M., Geda, Y. E. & Jack, C. R., Jan 2016, In : JAMA neurology. 73, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

87 Scopus citations
47 Scopus citations

Association of hypometabolism and amyloid levels in aging, normal subjects

Lowe, V. J., Weigand, S. D., Senjem, M. L., Vemuri, P., Jordan, L., Kantarci, K., Boeve, B., Jack, C. R., Knopman, D. & Petersen, R. C., Jun 3 2014, In : Neurology. 82, 22, p. 1959-1967 9 p.

Research output: Contribution to journalArticle

53 Scopus citations

Association of kidney function biomarkers with brain MRI findings: The BRINK study

Vemuri, P., Knopman, D. S., Jack, C. R., Lundt, E. S., Weigand, S. D., Zuk, S. M., Thostenson, K. B., Reid, R. I., Kantarci, K., Slinin, Y., Lakshminarayan, K., Davey, C. S. & Murray, A., 2017, In : Journal of Alzheimer's Disease. 55, 3, p. 1069-1082 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Association of lifetime intellectual enrichment with cognitive decline in the older population

Vemuri, P., Lesnick, T. G., Przybelski, S. A., Machulda, M., Knopman, D. S., Mielke, M. M., Roberts, R. O., Geda, Y. E., Rocca, W. A., Petersen, R. C. & Jack, C. R., Aug 2014, In : JAMA neurology. 71, 8, p. 1017-1024 8 p.

Research output: Contribution to journalArticle

87 Scopus citations
Open Access

Association of mid-life serum lipid levels with late-life brain volumes: The atherosclerosis risk in communities neurocognitive study (ARIC–NCS)

Moazzami, K., Power, M. C., Gottesman, R., Mosley, T., Lutsey, P. L., Jack, C. R., Hoogeveen, R. C., West, N., Knopman, D. S. & Alonso, A., Dec 2020, In : NeuroImage. 223, 117324.

Research output: Contribution to journalArticle

Open Access

Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

Alzheimer's Disease Neuroimaging Initiative, May 2017, In : JAMA neurology. 74, 5, p. 557-566 10 p.

Research output: Contribution to journalArticle

220 Scopus citations

Association of plasma total tau level with cognitive decline and risk of mild cognitive impairment or dementia in the Mayo Clinic study on aging

Mielke, M. M., Hagen, C. E., Wennberg, A. M. V., Airey, D. C., Savica, R., Knopman, D. S., Machulda, M. M., Roberts, R. O., Jack, C. R., Petersen, R. C. & Dage, J. L., Sep 2017, In : JAMA neurology. 74, 9, p. 1073-1080 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

Association of type 2 diabetes with brain atrophy and cognitive impairment

Roberts, R. O., Knopman, D. S., Przybelski, S. A., Mielke, M. M., Kantarci, K., Preboske, G. M., Senjem, M. L., Pankratz, V. S., Geda, Y. E., Boeve, B. F., Ivnik, R. J., Rocca, W. A., Petersen, R. C. & Jack, C. R., Apr 1 2014, In : Neurology. 82, 13, p. 1132-1141 10 p.

Research output: Contribution to journalArticle

106 Scopus citations

Association of white matter microstructural integrity with cognition and dementia

Power, M. C., Su, D., Wu, A., Reid, R. I., Jack, C. R., Knopman, D. S., Coresh, J., Huang, J., Kantarci, K., Sharrett, A. R., Gottesman, R. G., Griswold, M. E. & Mosley, T. H., Nov 2019, In : Neurobiology of aging. 83, p. 63-72 10 p.

Research output: Contribution to journalArticle

3 Scopus citations
1 Scopus citations
27 Scopus citations

Associations of Brain Structure With Adiposity and Changes in Adiposity in a Middle-Aged and Older Biracial Population

Windham, B. G., Lirette, S. T., Fornage, M., Benjamin, E. J., Parker, K. G., Turner, S. T., Jack, C. R., Griswold, M. E. & Mosley, T. H., Jun 1 2017, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 72, 6, p. 825-831 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Atrial Fibrillation, Brain Volumes, and Subclinical Cerebrovascular Disease (from the Atherosclerosis Risk in Communities Neurocognitive Study [ARIC-NCS])

Moazzami, K., Shao, I. Y., Chen, L. Y., Lutsey, P. L., Jack, C. R., Mosley, T., Joyner, D. A., Gottesman, R. & Alonso, A., Jan 1 2019, (Accepted/In press) In : American Journal of Cardiology.

Research output: Contribution to journalArticle

Atrial fibrillation, cognitive impairment, and neuroimaging

Graff-Radford, J., Madhavan, M., Vemuri, P., Rabinstein, A. A., Cha, R. H., Mielke, M. M., Kantarci, K., Lowe, V., Senjem, M. L., Gunter, J. L., Knopman, D. S., Petersen, R. C., Jack, C. R. & Roberts, R. O., Apr 1 2016, In : Alzheimer's and Dementia. 12, 4, p. 391-398 8 p.

Research output: Contribution to journalArticle

32 Scopus citations
5 Scopus citations

AV-1451 tau and β-amyloid positron emission tomography imaging in dementia with Lewy bodies

Kantarci, K., Lowe, V. J., Boeve, B. F., Senjem, M. L., Tosakulwong, N., Lesnick, T. G., Spychalla, A. J., Gunter, J. L., Fields, J. A., Graff-Radford, J., Ferman, T. J., Jones, D. T., Murray, M. E., Knopman, D. S., Jack, C. R. & Petersen, R. C., Jan 1 2017, In : Annals of neurology. 81, 1, p. 58-67 10 p.

Research output: Contribution to journalArticle

72 Scopus citations

Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults

Arenaza-Urquijo, E. M., Przybelski, S. A., MacHulda, M. M., Knopman, D. S., Lowe, V. J., Mielke, M. M., Reddy, A. L., Geda, Y. E., Jack, C. R., Petersen, R. C. & Vemuri, P., Apr 14 2020, In : Neurology. 94, 15, p. E1571-E1579

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Brain amyloid, cortical thickness, and changes in activities of daily living

Vassilaki, M., Aakre, J. A., Kremers, W. K., Lesnick, T. G., Mielke, M. M., Geda, Y. E., Machulda, M. M., Knopman, D. S., Butler, L., Traber, M., Vemuri, P., Lowe, V. J., Jack, C. R., Roberts, R. O. & Petersen, R. C., Apr 1 2020, In : Annals of Clinical and Translational Neurology. 7, 4, p. 474-485 12 p.

Research output: Contribution to journalArticle

Open Access

Brain amyloidosis ascertainment from cognitive, imaging, and peripheral blood protein measures

Alzheimer's Disease Neuroimaging Initiative, Feb 17 2015, In : Neurology. 84, 7, p. 729-737 9 p.

Research output: Contribution to journalArticle

23 Scopus citations
6 Scopus citations

Brain atrophy over time in genetic and sporadic frontotemporal dementia: A study of 198 serial magnetic resonance images

Whitwell, J. L., Boeve, B. F., Weigand, S. D., Senjem, M. L., Gunter, J. L., Baker, M. C., Dejesus-Hernandez, M., Knopman, D. S., Wszolek, Z. K., Petersen, R. C., Rademakers, R., Jack, C. R. & Josephs, K. A., May 1 2015, In : European Journal of Neurology. 22, 5, p. 745-752 8 p.

Research output: Contribution to journalArticle

60 Scopus citations