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  • Thomas Elmer Witzig
2017

Maintenance lenalidomide for large-cell lymphoma: Who really benefits?

Witzig, T. E., Aug 1 2017, In : Journal of Clinical Oncology. 35, 22

Research output: Contribution to journalEditorial

1 Scopus citations
4 Scopus citations
2019

Erratum: Phase I trial of rituximab, cladribine, and temsirolimus (rct) for initial therapy of mantle cell lymphoma (Annals of Oncology (2014) 25 (2020-2024) DOI: 10.1093/annonc/mdu273)

Inwards, D. J., Fishkin, P. A., Laplant, B. R., Drake, M. T., Kurtin, P. J., Nikcevich, D. A., Wender, D. B., Lair, B. S. & Witzig, T. E., Feb 1 2019, In : Annals of Oncology. 30, 2, 1 p.

Research output: Contribution to journalComment/debate

Open Access
2017

Accuracy of 18-F FDG PET/CT to detect bone marrow clearance in patients with peripheral T-cell lymphoma – tissue remains the issue

Pham, A. Q., Broski, S., Habermann, T. M., Jevremovic, D., Wiseman, G. A., Feldman, A. L., Maurer, M. J., Ristow, K. M. & Witzig, T. E., Mar 14 2017, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-7 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2019

Work-Life Balance Solutions for Physicians—It's All About You, Your Work, and Others

Witzig, T. E. & Smith, S. M., Apr 1 2019, In : Mayo Clinic proceedings. 94, 4, p. 573-576 4 p.

Research output: Contribution to journalShort survey

2 Scopus citations
2018

A First-in-Human Phase I Study of OPB-111077, a Small-Molecule STAT3 and Oxidative Phosphorylation Inhibitor, in Patients with Advanced Cancers

Tolcher, A., Flaherty, K., Shapiro, G. I., Berlin, J., Witzig, T. E., Habermann, T. M., Bullock, A., Rock, E., Elekes, A., Lin, C., Kostic, D., Ohi, N., Rasco, D., Papadopoulos, K. P., Patnaik, A., Smith, L. & Cote, G. M., Jun 1 2018, In : Oncologist. 23, 6, p. 658-e72

Research output: Contribution to journalArticle

13 Scopus citations
2020

Variable global distribution of cell-of-origin from the ROBUST phase III study in diffuse large B-cell lymphoma

Nowakowski, G. S., Chiappella, A., Witzig, T. E., Scott, D. W., Spina, M., Gascoyne, R. D., Zhang, L., Russo, J., Kang, J., Zhang, J., Xu, Y. & Vitolo, U., Jan 31 2020, In : Haematologica. 105, 2, p. E72-E75

Research output: Contribution to journalLetter

Open Access
2016

Definition of bulky disease in early stage hodgkin lymphoma in computed tomography era: Prognostic significance of measurements in the coronal and transverse planes

Kumar, A., Burger, I. A., Zhang, Z., Drill, E. N., Migliacci, J. C., Ng, A., Lacasce, A., Wall, D., Witzig, T. E., Ristow, K., Yahalom, J., Moskowitz, C. H. & Zelenetz, A. D., Sep 30 2016, In : Haematologica. 101, 10, p. 1237-1243 7 p.

Research output: Contribution to journalArticle

10 Scopus citations
2018
5 Scopus citations
2019

DNA demethylation and epigenetics

Zhang, X., Witzig, T. E. & Wu, X., Jan 5 2019, Handbook of Nutrition, Diet, and Epigenetics. Springer International Publishing, Vol. 1. p. 281-292 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Primary Cutaneous Acral CD8+ T-Cell Lymphoma-A Single Center Review of 3 Cases and Recent Literature Review

Tjahjono, L. A., Davis, M. D. P., Witzig, T. E. & Comfere, N. I., Sep 1 2019, In : The American Journal of dermatopathology. 41, 9, p. 644-648 5 p.

Research output: Contribution to journalReview article

1 Scopus citations
2016

Coinhibition of the deubiquitinating enzymes, USP14 and UCHL5, with VLX1570 is lethal to ibrutinib- or bortezomib-resistant Waldenstrom macroglobulinemia tumor cells

Paulus, A., Akhtar, S., Caulfield, T., Samuel, K., Yousaf, H., Bashir, Y., Paulus, S. M., Tran, D., Hudec, R., Cogen, D., Jiang, J., Edenfield, B., Novak, A. J., Ansell, S. M., Witzig, T. E., Martin, P., Coleman, M., Roy, V., Ailawadhi, S., Chitta, K. & 2 others, Linder, S. & Chanan Khan, A. A., Nov 4 2016, In : Blood Cancer Journal. 6, 11, e492.

Research output: Contribution to journalArticle

20 Scopus citations
27 Scopus citations
2018

Rapid, real time pathology review for ECOG/ACRIN 1412: A novel and successful paradigm for future lymphoma clinical trials in the precision medicine era

King, R., Nowakowski, G. S., Witzig, T. E., Scott, D. W., Little, R. F., Hong, F., Gascoyne, R. D., Kahl, B. S. & Macon, W. R., Mar 1 2018, In : Blood Cancer Journal. 8, 3, 27.

Research output: Contribution to journalReview article

4 Scopus citations
2017

A phase 2/3 multicenter, randomized, open-label study to compare the efficacy and safety of lenalidomide versus investigator's choice in patients with relapsed or refractory diffuse large B-cell lymphoma

Czuczman, M. S., Trněný, M., Davies, A., Rule, S., Linton, K. M., Wagner-Johnston, N., Gascoyne, R. D., Slack, G. W., Brousset, P., Eberhard, D. A., Hernandez-Ilizaliturri, F. J., Salles, G., Witzig, T. E., Zinzani, P. L., Wright, G. W., Staudt, L. M., Yang, Y., Williams, P. M., Lih, C. J., Russo, J. & 5 others, Thakurta, A., Hagner, P., Fustier, P., Song, D. & Lewis, I. D., Aug 1 2017, In : Clinical Cancer Research. 23, 15, p. 4127-4137 11 p.

Research output: Contribution to journalArticle

46 Scopus citations
2016

Anti-CD20 monoclonal antibody-dependent phagocytosis of chronic lymphocytic leukaemia cells by autologous macrophages

Church, A. K., Vandermeid, K. R., Baig, N. A., Baran, A. M., Witzig, T. E., Nowakowski, G. S. & Zent, C. S., Jan 1 2016, In : Clinical and Experimental Immunology. 183, 1, p. 90-101 12 p.

Research output: Contribution to journalArticle

19 Scopus citations
2017
4 Scopus citations

Axicabtagene ciloleucel CAR T-cell therapy in refractory large B-Cell lymphoma

Neelapu, S. S., Locke, F. L., Bartlett, N. L., Lekakis, L. J., Miklos, D. B., Jacobson, C. A., Braunschweig, I., Oluwole, O. O., Siddiqi, T., Lin, Y., Timmerman, J. M., Stiff, P. J., Friedberg, J. W., Flinn, I. W., Goy, A., Hill, B. T., Smith, M. R., Deol, A., Farooq, U., McSweeney, P. & 20 others, Munoz, J., Avivi, I., Castro, J. E., Westin, J. R., Chavez, J. C., Ghobadi, A., Komanduri, K. V., Levy, R., Jacobsen, E. D., Witzig, T. E., Reagan, P., Bot, A., Rossi, J., Navale, L., Jiang, Y., Aycock, J., Elias, M., Chang, D., Wiezorek, J. & Go, W. Y., Dec 28 2017, In : New England Journal of Medicine. 377, 26, p. 2531-2544 14 p.

Research output: Contribution to journalArticle

787 Scopus citations
2018

Targetable fusions of the FRK tyrosine kinase in ALKnegative anaplastic large cell lymphoma

Hu, G., Dasari, S., Asmann, Y., Greipp, P. T., Knudson, R. A., Benson, H. K., Li, Y., Eckloff, B. W., Jen, J., Link, B. K., Jiang, L., Sidhu, J. S., Wellik, L. E., Witzig, T. E., Bennani, N., Cerhan, J. R., Luchtel, R. & Feldman, A. L., Feb 1 2018, In : Leukemia. 32, 2, p. 565-569 5 p.

Research output: Contribution to journalLetter

8 Scopus citations
2017
6 Scopus citations

Efficacy of the oral mTORC1 inhibitor everolimus in relapsed or refractory indolent lymphoma

Bennani, N., LaPlant, B. R., Ansell, S. M., Habermann, T. M., Inwards, D. J., Micallef, I., Johnston, P. B., Porrata, L. F., Colgan, J. P., Markovic, S. N., Nowakowski, G. S., Macon, W. R., Reeder, C. B., Mikhael, J. R., Northfelt, D. W., Ghobrial, I. M. & Witzig, T. E., May 1 2017, In : American Journal of Hematology. 92, 5, p. 448-453 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Vitamin D insufficiency is associated with an increased risk of early clinical failure in follicular lymphoma

Tracy, S. I., Maurer, M. J., Witzig, T. E., Drake, M. M., Ansell, S. M., Nowakowski, G. S., Thompson, C. A., Inwards, D. J., Johnston, P. B., Micallef, I., Allmer, C., MacOn, W. R., Weiner, G. J., Slager, S. L., Habermann, T. M., Link, B. K. & Cerhan, J. R., Aug 25 2017, In : Blood Cancer Journal. 7, 8, e595.

Research output: Contribution to journalArticle

6 Scopus citations
2019

Host genetic variation in tumor necrosis factor and nuclear factor-κB pathways and overall survival in mantle cell lymphoma: A discovery and replication study

Wang, Y., Habermann, T. M., Wang, S. S., Maurer, M. J., Sarangi, V., Link, B. K., Feldman, A. L., Inwards, D. J., Witzig, T. E., Cozen, W., Rothman, N., Asmann, Y., Slager, S. L. & Cerhan, J. R., Jun 2019, In : American journal of hematology. 94, 6, p. E153-E155

Research output: Contribution to journalLetter

Open Access

Impact of concurrent indolent lymphoma on the clinical outcome of newly diagnosed diffuse large B-cell lymphoma

Wang, Y., Link, B. K., Witzig, T. E., Maurer, M. J., Allmer, C., King, R. L., Feldman, A. L., Habermann, T. M., Ansell, S. M., Slager, S. L., Cerhan, J. R. & Nowakowski, G. S., Oct 17 2019, In : Blood. 134, 16, p. 1289-1297 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2017
3 Scopus citations
2016

Early event status informs subsequent outcome in newly diagnosed follicular lymphoma

Maurer, M. J., Bachy, E., Ghesquières, H., Ansell, S. M., Nowakowski, G. S., Thompson, C. A., Inwards, D. J., Allmer, C., Chassagne-Clément, C., Nicolas-Virelizier, E., Sebban, C., Lebras, L., Sarkozy, C., Macon, W. R., Feldman, A. L., Syrbu, S. I., Traverse-Glehan, A., Coiffier, B., Slager, S. L., Weiner, G. J. & 5 others, Witzig, T. E., Habermann, T. M., Salles, G., Cerhan, J. R. & Link, B. K., 2016, (Accepted/In press) In : American Journal of Hematology.

Research output: Contribution to journalArticle

85 Scopus citations

Personalized risk prediction for event-free survival at 24 months in patients with diffuse large B-cell lymphoma

Maurer, M. J., Jais, J. P., Ghesquières, H., Witzig, T. E., Hong, F., Haioun, C., Thompson, C. A., Thieblemont, C., Micallef, I. N., Porrata, L. F., Ribrag, V., Nowakowski, G. S., Casasnovas, O., Bologna, S., Morschhauser, F., Morrison, V. A., Peterson, B. A., Macon, W. R., Copie-Bergman, C., Feldman, A. L. & 13 others, Syrbu, S. I., Kurtin, P. J., Gascoyne, R. D., Li, H., Allmer, C., Kahl, B. S., Ansell, S. M., Slager, S. L., Link, B. K., Salles, G., Habermann, T. M., Tilly, H. & Cerhan, J. R., Feb 1 2016, In : American journal of hematology. 91, 2, p. 179-184 6 p.

Research output: Contribution to journalArticle

18 Scopus citations
2017

Upregulation of TET activity with ascorbic acid induces epigenetic modulation of lymphoma cells

Shenoy, N., Bhagat, T., Nieves, E., Stenson, M., Lawson, J., Choudhary, G. S., Habermann, T. M., Nowakowski, G. S., Singh, R. J., Wu, X., Verma, A. & Witzig, T. E., Jul 21 2017, In : Blood Cancer Journal. 7, 7, p. e587

Research output: Contribution to journalArticle

25 Scopus citations
48 Scopus citations

Dexamethasone, rituximab and cyclophosphamide for relapsed and/or refractory and treatment-naïve patients with Waldenstrom macroglobulinemia

Paludo, J., Abeykoon, J. P., Kumar, S., Shreders, A., Ailawadhi, S., Gertz, M. A., Kourelis, T., King, R. L., Reeder, C. B., Leung, N., Kyle, R. A., Buadi, F. K., Habermann, T. M., Dingli, D., Witzig, T. E., Dispenzieri, A., Lacy, M. Q., Go, R. S., Lin, Y., Gonsalves, W. I. & 5 others, Warsame, R., Lust, J. A., Rajkumar, S. V., Ansell, S. M. & Kapoor, P., Oct 2017, In : British journal of haematology. 179, 1, p. 98-105 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
2018

MYD88 mutation status does not impact overall survival in Waldenström macroglobulinemia

Abeykoon, J. P., Paludo, J., King, R., Ansell, S. M., Gertz, M., LaPlant, B. R., Halvorson, A. E., Gonsalves, W., Dingli, D. M., Fang, H., Rajkumar, S. V., Lacy, M., He, R., Kourelis, T., Reeder, C. B., Novak, A. J., McPhail, E., Viswanatha, D. S., Witzig, T. E., Go, R. S. & 10 others, Habermann, T. M., Buadi, F. K., Dispenzieri, A., Leung, N., Lin, Y., Thompson, C. A., Hayman, S. R., Kyle, R. A., Kumar, S. K. & Kapoor, P., Feb 1 2018, In : American Journal of Hematology. 93, 2, p. 187-194 8 p.

Research output: Contribution to journalArticle

22 Scopus citations
2020

Magnesium: The overlooked electrolyte in blood cancers?

Gile, J., Ruan, G., Abeykoon, J., McMahon, M. M. & Witzig, T., Jan 1 2020, (Accepted/In press) In : Blood Reviews. 100676.

Research output: Contribution to journalReview article

1 Scopus citations

Hypomagnesemia is associated with an increased risk of early clinical failure in patients with Burkitt lymphoma

Gile, J., Ruan, G., Abeykoon, J., McMahon, M. M., Macon, W. R. & Witzig, T. E., Jan 1 2020, (Accepted/In press) In : Leukemia and Lymphoma.

Research output: Contribution to journalLetter

2019

Acalabrutinib for mantle cell lymphoma

Witzig, T. E. & Inwards, D., Jan 1 2019, In : Blood. 133, 24, p. 2570-2574 5 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Adjuvant everolimus in high-risk diffuse large B-cell lymphoma: Final results from the PILLAR-2 randomized phase III trial

Witzig, T. E., Tobinai, K., Rigacci, L., Ikeda, T., Vanazzi, A., Hino, M., Shi, Y., Mayer, J., Costa, L. J., Bermudez Silva, C. D., Zhu, J., Belada, D., Bouabdallah, K., Kattan, J. G., Kuruvilla, J., Kim, W. S., Larouche, J. F., Ogura, M., Ozcan, M., Fayad, L. & 5 others, Wu, C., Fan, J., Louveau, A. L., Voi, M. & Cavalli, F., Mar 1 2018, In : Annals of Oncology. 29, 3, p. 707-714 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
2017

Pseudo-monoclonal gammopathy: A report of four cases

Jawad, M. D., Go, R. S., Witzig, T. E., Mikhae, J. R., Ravindran, A. & Murrray, D. L., Oct 27 2017, In : Haematologica. 102, 11, p. e466-e469

Research output: Contribution to journalArticle

3 Scopus citations
2018

Acute coronary syndromes in patients with active hematologic malignancies – Incidence, management, and outcomes

Park, J. Y., Guo, W., Al-Hijji, M., El Sabbagh, A., Begna, K., Habermann, T. M., Witzig, T. E., Lewis, B. R., Lerman, A. & Herrmann, J., Jan 1 2018, (Accepted/In press) In : International Journal of Cardiology.

Research output: Contribution to journalArticle

8 Scopus citations
2019

Citron Rho-interacting kinase silencing causes cytokinesis failure and reduces tumor growth in multiple myeloma

Sahin, I., Kawano, Y., Sklavenitis-Pistofidis, R., Moschetta, M., Mishima, Y., Manier, S., Sacco, A., Carrasco, R., Fonseca, R., Roccaro, A. M., Witzig, T. & Ghobrial, I. M., Apr 9 2019, In : Blood Advances. 3, 7, p. 995-1002 8 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2016
43 Scopus citations
2018

Prognostic and therapeutic significance of phosphorylated STAT3 and protein tyrosine phosphatase-6 in peripheral-T cell lymphoma

Han, J. J., O’byrne, M., Stenson, M. J., Maurer, M. J., Wellik, L. E., Feldman, A. L., McPhail, E. D., Witzig, T. E. & Gupta, M., Nov 1 2018, In : Blood cancer journal. 8, 11, 110.

Research output: Contribution to journalArticle

5 Scopus citations

Inferior survival in high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements is not associated with MYC/IG gene rearrangements

McPhail, E., Maurer, M. J., Macon, W. R., Feldman, A. L., Kurtin, P. J., Ketterling, R. P., Vaidya, R., Cerhan, J. R., Ansell, S. M., Porrata, L. F., Nowakowski, G. S., Witzig, T. E. & Habermann, T. M., Nov 1 2018, In : Haematologica. 103, 11, p. 1899-1907 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
2019

Late relapses in patients with diffuse large b-cell lymphoma treated with immunochemotherapy

Wang, Y., Farooq, U., Link, B. K., Larson, M. C., King, R., Maurer, M. J., Allmer, C., Hefazi, M., Thompson, C. A., Micallef, I., Johnston, P. B., Habermann, T. M., Witzig, T. E., Ansell, S. M., Cerhan, J. R. & Nowakowski, G. S., Jul 20 2019, In : Journal of Clinical Oncology. 37, 21, p. 1819-1827 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
2020

Persistent mediastinal FDG uptake on PET-CT after frontline therapy for Hodgkin lymphoma: biopsy, treat or observe?

Novo, M., Nowakowski, G. S., Habermann, T. M., Witzig, T. E., Micallef, I. N., Johnston, P. B., Inwards, D. J., Botto, B., Ristow, K. M., Young, J. R., Vitolo, U. & Ansell, S. M., Jan 28 2020, In : Leukemia and Lymphoma. 61, 2, p. 318-327 10 p.

Research output: Contribution to journalArticle

2017

Low hypoxia inducible factor-1α (HIF-1α) expression in testicular germ cell tumors — a major reason for enhanced chemosensitivity?

Shenoy, N., Dronca, R. S., Quevedo, F., Boorjian, S. A., Cheville, J., Costello, B., Kohli, M., Witzig, T. E. & Pagliaro, L., Aug 1 2017, In : Chinese Journal of Cancer Research. 29, 4, p. 374-378 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Risk of histological transformation and therapy-related myelodysplasia/acute myeloid leukaemia in patients receiving radioimmunotherapy for follicular lymphoma

Epperla, N., Pham, A. Q., Burnette, B. L., Wiseman, G. A., Habermann, T. M., Macon, W. R., Ansell, S. M., Inwards, D. J., Micallef, I., Johnston, P. B., Markovic, S. N., Porrata, L. F., Colgan, J. P., Ristow, K. M., Nowakowski, G. S. & Witzig, T. E., 2017, (Accepted/In press) In : British Journal of Haematology.

Research output: Contribution to journalArticle

7 Scopus citations
2018

A phase 2 study of rituximab, cyclophosphamide, bortezomib and dexamethasone (R-CyBorD) in relapsed low grade and mantle cell lymphoma

Sonbol, M. B., Hilal, T., Dueck, A., Rosenthal, A. C., Conley, C. R., Kosiorek, H. E., Ginos, B. F., Gano, K. M., Nichols, C. S., Leis, J. F., Johnston, P. B., Habermann, T. M., Northfelt, D. W., Bergsagel, P. L., Inwards, D. J., Witzig, T. E., Ansell, S. M. & Reeder, C. B., Jan 11 2018, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-7 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

A Novel Combination of the mTORC1 Inhibitor Everolimus and the Immunomodulatory Drug Lenalidomide Produces Durable Responses in Patients With Heavily Pretreated Relapsed Lymphoma

Padrnos, L., Ernst, B., Dueck, A., Kosiorek, H. E., Ginos, B. F., Toro, A., Johnston, P. B., Habermann, T. M., Leis, J. F., Mikhael, J. R., Nowakowski, G. S., Colgan, J., Porrata, L., Ansell, S. M., Witzig, T. E. & Reeder, C., Jan 1 2018, (Accepted/In press) In : Clinical Lymphoma, Myeloma and Leukemia.

Research output: Contribution to journalArticle

1 Scopus citations

Ascorbic Acid in Cancer Treatment: Let the Phoenix Fly

Shenoy, N., Creagan, E., Witzig, T. E. & Levine, M., Nov 12 2018, In : Cancer Cell. 34, 5, p. 700-706 7 p.

Research output: Contribution to journalReview article

26 Scopus citations