Find Research Outputs

Search concepts
Selected Filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016

Author

  • Michael John Ackerman
2017

Beta-blocker therapy for long QT syndrome and catecholaminergic polymorphic ventricular tachycardia: Are all beta-blockers equivalent?

Ackerman, M. J., Priori, S. G., Dubin, A. M., Kowey, P., Linker, N. J., Slotwiner, D., Triedman, J., Van Hare, G. F. & Gold, M. R., Jan 1 2017, In : Heart Rhythm. 14, 1, p. e41-e44

Research output: Contribution to journalArticle

23 Scopus citations
2016

Sites of Successful Ventricular Fibrillation Ablation in Bileaflet Mitral Valve Prolapse Syndrome

Syed, F. F., Ackerman, M. J., McLeod, C. J., Kapa, S., Mulpuru, S. K., Sriram, C. S., Cannon, B. C., Asirvatham, S. J. & Noseworthy, P. A., May 1 2016, In : Circulation: Arrhythmia and Electrophysiology. 9, 5, e004005.

Research output: Contribution to journalArticle

31 Scopus citations
2018

2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: Executive summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society

Al-Khatib, S. M., Stevenson, W. G., Ackerman, M. J., Bryant, W. J., Callans, D. J., Curtis, A. B., Deal, B. J., Dickfeld, T., Field, M. E., Fonarow, G. C., Gillis, A. M., Granger, C. B., Hammill, S. C., Hlatky, M. A., Joglar, J. A., Kay, G. N., Matlock, D. D., Myerburg, R. J. & Page, R. L., Oct 1 2018, In : Heart Rhythm. 15, 10, p. e190-e252

Research output: Contribution to journalArticle

126 Scopus citations
2016

Identification of concealed and manifest long QT syndrome using a novel T wave analysis program

Sugrue, A., Noseworthy, P. A., Kremen, V., Bos, J. M., Qiang, B., Rohatgi, R. K., Sapir, Y., Attia, Z. I., Brady, P., Asirvatham, S. J., Friedman, P. A. & Ackerman, M. J., Jul 1 2016, In : Circulation: Arrhythmia and Electrophysiology. 9, 7

Research output: Contribution to journalArticle

9 Scopus citations
2018

Perioperative management of patients with congenital or acquired disorders of the QT interval

O'Hare, M., Maldonado, Y., Munro, J., Ackerman, M. J., Ramakrishna, H. & Sorajja, D., Apr 1 2018, In : British Journal of Anaesthesia. 120, 4, p. 629-644 16 p.

Research output: Contribution to journalReview article

2 Scopus citations
2016

Enhancing Literacy in Cardiovascular Genetics: A Scientific Statement from the American Heart Association

Mital, S., Musunuru, K., Garg, V., Russell, M. W., Lanfear, D. E., Gupta, R. M., Hickey, K. T., Ackerman, M. J., Perez, M. V., Roden, D. M., Woo, D., Fox, C. S. & Ware, S., Oct 1 2016, In : Circulation: Cardiovascular Genetics. 9, 5, p. 448-467 20 p.

Research output: Contribution to journalArticle

26 Scopus citations
2019

Electrophysiologic effects and outcomes of sympatholysis in patients with recurrent ventricular arrhythmia and structural heart disease

Cai, C., Dai, M. Y., Tian, Y., Zhang, P., Wittwer, E. D., Rho, R. H., Kapa, S., McLeod, C. J., Mulpuru, S., Lee, H. C., Ackerman, M. J., Asirvatham, S. J., Munger, T. M., Chen, M. L., Friedman, P. A. & Cha, Y-M., Sep 1 2019, In : Journal of cardiovascular electrophysiology. 30, 9, p. 1499-1507 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

QT prolongation and sudden cardiac death risk in hypertrophic cardiomyopathy

Patel, S. I., Ackerman, M. J., Shamoun, F. E., Geske, J. B., Ommen, S. R., Love, W. T., Cha, S. S., Bos, J. M. & Lester, S. J., Mar 6 2018, (Accepted/In press) In : Acta Cardiologica. p. 1-6 6 p.

Research output: Contribution to journalArticle

3 Scopus citations
2019

The Effect of Left Cardiac Sympathetic Denervation on Exercise in Patients With Long QT Syndrome

Anderson, H. N., Bos, J. M., Rohatgi, R. K. & Ackerman, M. J., Sep 1 2019, In : JACC: Clinical Electrophysiology. 5, 9, p. 1084-1090 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016
1 Scopus citations
2018

Adaptation and validation of the ACMG/AMP variant classification framework for MYH7-associated inherited cardiomyopathies: Recommendations by ClinGen's Inherited Cardiomyopathy Expert Panel

ClinGen Cardiovascular Clinical Domain Working Group, Mar 1 2018, In : Genetics in Medicine. 20, 3, p. 351-359 9 p.

Research output: Contribution to journalArticle

67 Scopus citations
2016

Novel bloodless potassium determination using a signal-processed single-lead ECG

Attia, Z. I., DeSimone, C. V., Dillon, J. J., Sapir, Y., Somers, V., Dugan, J. L., Bruce, C. J., Ackerman, M. J., Asirvatham, S. J., Striemer, B. L., Bukartyk, J., Scott, C. G., Bennet, K. E., Ladewig, D. J., Gilles, E. J., Sadot, D., Geva, A. B. & Friedman, P. A., 2016, In : Journal of the American Heart Association. 5, 1, e002746.

Research output: Contribution to journalArticle

16 Scopus citations
2017

Evaluating the survivor or the relatives of those who do not survive: The role of genetic testing

Tester, D. J. & Ackerman, M. J., Jan 1 2017, In : Cardiology in the Young. 27, S1, p. S19-S24

Research output: Contribution to journalReview article

1 Scopus citations
2018

Yield of the RYR2 Genetic Test in Suspected Catecholaminergic Polymorphic Ventricular Tachycardia and Implications for Test Interpretation

Kapplinger, J. D., Pundi, K. N., Larson, N., Callis, T. E., Tester, D. J., Bikker, H., Wilde, A. A. M. & Ackerman, M. J., Feb 1 2018, In : Circulation. Genomic and precision medicine. 11, 2, p. e001424

Research output: Contribution to journalArticle

11 Scopus citations

The genetic architecture of long QT syndrome: A critical reappraisal

Giudicessi, J. R., Wilde, A. A. M. & Ackerman, M. J., Jan 1 2018, (Accepted/In press) In : Trends in Cardiovascular Medicine.

Research output: Contribution to journalArticle

24 Scopus citations
2019

Stellate ganglion block and cardiac sympathetic denervation in patients with inappropriate sinus tachycardia

Cha, Y. M., Li, X., Yang, M., Han, J., Wu, G., Kapa, S. C., McLeod, C. J., Noseworthy, P. A., Mulpuru, S. K., Asirvatham, S. J., Brady, P. A., Rho, R. H., Friedman, P. A., Lee, H. C., Tian, Y., Zhou, S., Munger, T. M., Ackerman, M. J. & Shen, W. K., Jan 1 2019, (Accepted/In press) In : Journal of cardiovascular electrophysiology.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Heritability in genetic heart disease: The role of genetic background

Jansweijer, J. A., Van Spaendonck-Zwarts, K. Y., Tanck, M. W. T., Peter Van Tintelen, J., Christiaans, I., Van Der Smagt, J., Vermeer, A., Bos, J. M., Moss, A. J., Swan, H., Priori, S., Rydberg, A., Tfelt-Hansen, J., Ackerman, M., Olivotto, I., Charron, P., Gimeno, J. R., Van Den Berg, M., Wilde, A. & Pinto, Y. M., May 1 2019, In : Open Heart. 6, 1, e000929.

Research output: Contribution to journalArticle

Open Access
2018

Genetic testing in athletes

Tester, D. J. & Ackerman, M. J., Apr 20 2018, Exercise Risks, Cardiac Arrhythmias and Unusual Problems in Athletes. World Scientific Publishing Co. Pte Ltd, Vol. 3-3. p. 41-74 34 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2017

MYBPC3 mutations are associated with a reduced super-relaxed state in patients with hypertrophic cardiomyopathy

McNamara, J. W., Li, A., Lal, S., Bos, J. M., Harris, S. P., Van Der Velden, J., Ackerman, M. J., Cooke, R. & Dos Remedios, C. G., Jun 2017, In : PloS one. 12, 6, e0180064.

Research output: Contribution to journalArticle

32 Scopus citations
2016

Does Sudden Unexplained Nocturnal Death Syndrome Remain the Autopsy-Negative Disorder: A Gross, Microscopic, and Molecular Autopsy Investigation in Southern China

Zhang, L., Tester, D. J., Lang, D., Chen, Y., Zheng, J., Gao, R., Corliss, R. F., Tang, S., Kyle, J. W., Liu, C., Ackerman, M. J., Makielski, J. C. & Cheng, J., Nov 1 2016, In : Mayo Clinic Proceedings. 91, 11, p. 1503-1514 12 p.

Research output: Contribution to journalArticle

15 Scopus citations
2018

Effect of Body Mass Index on Exercise Capacity in Patients With Hypertrophic Cardiomyopathy

Larsen, C. M., Ball, C. A., Hebl, V. B., Ong, K. C., Siontis, K. C., Olson, T. P., Ackerman, M. J., Ommen, S. R., Allison, T. G. & Geske, J. B., Jan 1 2018, In : American Journal of Cardiology. 121, 1, p. 100-106 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
2016

British Cardiovascular society annual conference 2016

Samani, S. N., Ackerman, M., Rea, T., Alice & Robert's, Jan 1 2016, In : European heart journal. 37, 34, p. 2621-2625 5 p.

Research output: Contribution to journalArticle

2018

Functional Invalidation of Putative Sudden Infant Death Syndrome-Associated Variants in the KCNH2-Encoded Kv11.1 Channel

Smith, J. L., Tester, D. J., Hall, A. R., Burgess, D. E., Hsu, C. C., Elayi, S. C., Anderson, C. L., January, C. T., Luo, J. Z., Hartzel, D. N., Mirshahi, U. L., Murray, M. F., Mirshahi, T., Ackerman, M. J. & Delisle, B. P., May 1 2018, In : Circulation. Arrhythmia and electrophysiology. 11, 5, p. e005859

Research output: Contribution to journalArticle

1 Scopus citations
2019

Plakophilin-2 Truncation Variants in Patients Clinically Diagnosed With Catecholaminergic Polymorphic Ventricular Tachycardia and Decedents With Exercise-Associated Autopsy Negative Sudden Unexplained Death in the Young

Tester, D. J., Ackerman, J. P., Giudicessi, J. R., Ackerman, N. C., Cerrone, M., Delmar, M. & Ackerman, M. J., Jan 2019, In : JACC: Clinical Electrophysiology. 5, 1, p. 120-127 8 p.

Research output: Contribution to journalArticle

10 Scopus citations
2016

A case for inclusion of genetic counselors in cardiac care

Arscott, P., Caleshu, C., Kotzer, K., Kreykes, S., Kruisselbrink, T., Orland, K., Rigelsky, C., Smith, E., Spoonamore, K., Haidle, J. L., Marvin, M., Ackerman, M. J., Hadi, A., Mani, A., Ommen, S. & Cherny, S., Jan 1 2016, In : Cardiology in Review. 24, 2, p. 49-55 7 p.

Research output: Contribution to journalReview article

11 Scopus citations
2017

J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge

Antzelevitch, C., Yan, G. X., Ackerman, M. J., Borggrefe, M., Corrado, D., Guo, J., Gussak, I., Hasdemir, C., Horie, M., Huikuri, H., Ma, C., Morita, H., Nam, G. B., Sacher, F., Shimizu, W., Viskin, S. & Wilde, A. A. M., Apr 1 2017, In : Europace. 19, 4, p. 665-694 30 p.

Research output: Contribution to journalArticle

63 Scopus citations
2019

Utilization of the genome aggregation database, in silico tools, and heterologous expression patch-clamp studies to identify and demote previously published type 2 long QT syndrome: Causative variants from pathogenic to likely benign

Mattivi, C. L., Ye, D., Tester, D. J., Clemens, D. J., Zhou, W., Giudicessi, J. R. & Ackerman, M. J., Jan 1 2019, (Accepted/In press) In : Heart rhythm.

Research output: Contribution to journalArticle

The QT Interval

Giudicessi, J. R., Noseworthy, P. & Ackerman, M. J., Jun 11 2019, In : Circulation. 139, 24, p. 2711-2713 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

An autoantibody identifies arrhythmogenic right ventricular cardiomyopathy and participates in its pathogenesis

Chatterjee, D., Fatah, M., Akdis, D., Spears, D. A., Koopmann, T. T., Mittal, K., Rafiq, M. A., Cattanach, B. M., Zhao, Q., Healey, J. S., Ackerman, M. J., Bos, J. M., Sun, Y., Maynes, J. T., Brunckhorst, C., Medeiros-Domingo, A., Duru, F., Saguner, A. M. & Hamilton, R. M., Nov 21 2018, In : European Heart Journal. 39, 44, p. 3932-3944 13 p.

Research output: Contribution to journalArticle

25 Scopus citations
2019
5 Scopus citations

Cardiac hypertrophy and arrhythmia in mice induced by a mutation in ryanodine receptor 2

Alvarado, F. J., Martijn Bos, J., Yuchi, Z., Valdivia, C. R., Hernández, J. J., Zhao, Y. T., Henderlong, D. S., Chen, Y., Booher, T. R., Marcou, C. A., Van Petegem, F., Ackerman, M. J. & Valdivia, H. H., Jan 1 2019, In : JCI Insight. 4, 7, e126544.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Irritable bowel syndrome patients have SCN5A channelopathies that lead to decreased Na v 1.5 current and mechanosensitivity

Strege, P. R., Mazzone, A., Bernard, C. E., Neshatian, L., Gibbons, S. J., Saito, Y. A., Tester, D. J., Calvert, M. L., Mayer, E. A., Chang, L., Ackerman, M. J., Beyder, A. & Farrugia, G., Apr 2018, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 314, 4, p. G494-G503

Research output: Contribution to journalArticle

10 Scopus citations

SCN5A mutations in 442 neonates and children: Genotype-phenotype correlation and identification of higher-risk subgroups

Baruteau, A. E., Kyndt, F., Behr, E. R., Vink, A. S., Lachaud, M., Joong, A., Schott, J. J., Horie, M., Denjoy, I., Crotti, L., Shimizu, W., Bos, J. M., Stephenson, E. A., Wong, L., Abrams, D. J., Davis, A. M., Winbo, A., Dubin, A. M., Sanatani, S., Liberman, L. & 31 others, Kaski, J. P., Rudic, B., Kwok, S. Y., Rieubland, C., Tfelt-Hansen, J., Van Hare, G. F., Guyomarc'h-Delasalle, B., Blom, N. A., Wijeyeratne, Y. D., Gourraud, J. B., Marec, H. L., Ozawa, J., Fressart, V., Lupoglazoff, J. M., Dagradi, F., Spazzolini, C., Aiba, T., Tester, D. J., Zahavich, L. A., Beauséjour-Ladouceur, V., Jadhav, M., Skinner, J. R., Franciosi, S., Krahn, A. D., Abdelsayed, M., Ruben, P. C., Yung, T. C., Ackerman, M. J., Wilde, A. A., Schwartz, P. J. & Probst, V., Aug 1 2018, In : European heart journal. 39, 31, p. 2879-2887 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Return-to-play for athletes with genetic heart diseases

Turkowski, K. L., Martijn Bos, J., Ackerman, N. C., Rohatgi, R. K. & Ackerman, M. J., Mar 1 2018, In : Circulation. 137, 10, p. 1086-1088 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Potentially modifiable factors of dofetilide-associated risk of torsades de pointes among hospitalized patients with atrial fibrillation

Naksuk, N., Sugrue, A. M., Padmanabhan, D., Kella, D., DeSimone, C. V., Kapa, S., Asirvatham, S. J., Lee, H. C., Ackerman, M. J. & Noseworthy, P., Jan 1 2018, (Accepted/In press) In : Journal of Interventional Cardiac Electrophysiology.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Whole genome sequencing identifies etiology of recurrent male intrauterine fetal death

Shehab, O., Tester, D. J., Ackerman, N. C., Cowchock, F. S. & Ackerman, M. J., Oct 1 2017, In : Prenatal Diagnosis. 37, 10, p. 1040-1045 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Whole exome sequencing with genomic triangulation implicates CDH2-encoded N-cadherin as a novel pathogenic substrate for arrhythmogenic cardiomyopathy

Turkowski, K. L., Tester, D. J., Bos, J. M., Haugaa, K. H. & Ackerman, M. J., Mar 1 2017, In : Congenital Heart Disease. 12, 2, p. 226-235 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
2016

Post-Mortem Cardiovascular Implantable Electronic Device Interrogation: Clinical Indications and Potential Benefits

Ackerman, M. J. & Giudicessi, J. R., Sep 20 2016, In : Journal of the American College of Cardiology. 68, 12, p. 1265-1267 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations
2020

Identification of a Novel Homozygous Multi-Exon Duplication in RYR2 among Children with Exertion-Related Unexplained Sudden Deaths in the Amish Community

Tester, D. J., Bombei, H. M., Fitzgerald, K. K., Giudicessi, J. R., Pitel, B. A., Thorland, E. C., Russell, B. G., Hamrick, S. K., Kim, C. S. J., Haglund-Turnquist, C. M., Johnsrude, C. L., Atkins, D. L., Ochoa Nunez, L. A., Law, I., Temple, J. & Ackerman, M. J., Mar 2020, In : JAMA cardiology. 5, 3, p. 340-345 6 p.

Research output: Contribution to journalArticle

2018

Clinical Significance of Early Repolarization in Long QT Syndrome

Sugrue, A., Rohatgi, R. K., Bos, M., Vaidya, V. R., Asirvatham, S. J., Noseworthy, P. & Ackerman, M. J., Sep 1 2018, In : JACC: Clinical Electrophysiology. 4, 9, p. 1238-1244 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2016

Novel CPVT-Associated Calmodulin Mutation in CALM3 (CALM3-A103V) Activates Arrhythmogenic Ca Waves and Sparks

Gomez-Hurtado, N., Boczek, N. J., Kryshtal, D. O., Johnson, C. N., Sun, J., Nitu, F. R., Cornea, R. L., Chazin, W. J., Calvert, M. L., Tester, D. J., Ackerman, M. J. & Knollmann, B. C., Aug 1 2016, In : Circulation: Arrhythmia and Electrophysiology. 9, 8, e004161.

Research output: Contribution to journalArticle

31 Scopus citations

Whole Exome Sequencing, Familial Genomic Triangulation, and Systems Biology Converge to Identify a Novel Nonsense Mutation in TAB2-encoded TGF-beta Activated Kinase 1 in a Child with Polyvalvular Syndrome

Ackerman, J. P., Smestad, J. A., Tester, D. J., Qureshi, M. Y., Crabb, B. A., Mendelsohn, N. J. & Ackerman, M. J., Sep 1 2016, In : Congenital Heart Disease. 11, 5, p. 452-461 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
2019

Findings of Uncertain Significance and a Family History of Sudden Death: Worth the FUSs?

Ackerman, M. J. & Giudicessi, J. R., Aug 13 2019, In : Journal of the American College of Cardiology. 74, 6, p. 771-773 3 p.

Research output: Contribution to journalEditorial

2018

2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: Executive Summary

Al-Khatib, S. M., Stevenson, W. G., Ackerman, M. J., Bryant, W. J., Callans, D. J., Curtis, A. B., Deal, B. J., Dickfeld, T., Field, M. E., Fonarow, G. C., Gillis, A. M., Granger, C. B., Hammill, S. C., Hlatky, M. A., Joglar, J. A., Kay, G. N., Matlock, D. D., Myerburg, R. J. & Page, R. L., Sep 25 2018, In : Circulation. 138, 13, p. e210-e271

Research output: Contribution to journalArticle

76 Scopus citations
2019
Open Access
2 Scopus citations

Linking the heart and the brain: Neurodevelopmental disorders in patients with catecholaminergic polymorphic ventricular tachycardia

Lieve, K. V. V., Verhagen, J. M. A., Wei, J., Bos, J. M., van der Werf, C., Rosés i Noguer, F., Mancini, G. M. S., Guo, W., Wang, R., van den Heuvel, F., Frohn-Mulder, I. M. E., Shimizu, W., Nogami, A., Horigome, H., Roberts, J. D., Leenhardt, A., Crijns, H. J. G., Blank, A. C., Aiba, T., Wiesfeld, A. C. P. & 7 others, Blom, N. A., Sumitomo, N., Till, J., Ackerman, M. J., Chen, S. R. W., van de Laar, I. M. B. H. & Wilde, A. A. M., Feb 1 2019, In : Heart Rhythm. 16, 2, p. 220-228 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Effective Use of Percutaneous Stellate Ganglion Blockade in Patients with Electrical Storm

Tian, Y., Wittwer, E. D., Kapa, S., McLeod, C. J., Xiao, P., Noseworthy, P. A., Mulpuru, S. K., Deshmukh, A. J., Lee, H. C., Ackerman, M. J., Asirvatham, S. J., Munger, T. M., Liu, X. P., Friedman, P. A. & Cha, Y. M., Sep 1 2019, In : Circulation: Arrhythmia and Electrophysiology. 12, 9

Research output: Contribution to journalArticle

4 Scopus citations
2016

J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge. Endorsed by the Asia Pacific Heart Rhythm Society (APHRS), the European Heart Rhythm Association (EHRA), the Heart Rhythm Society (HRS), and the Latin American Society of Cardiac Pacing and Electrophysiology (Sociedad Latinoamericana de Estimulación Cardíaca y Elect

Antzelevitch, C., Yan, G. X., Ackerman, M. J., Borggrefe, M., Corrado, D., Guo, J., Gussak, I., Hasdemir, C., Horie, M., Huikuri, H., Ma, C., Morita, H., Nam, G. B., Sacher, F., Shimizu, W., Viskin, S. & Wilde, A. A. M., 2016, (Accepted/In press) In : Heart Rhythm.

Research output: Contribution to journalArticle

99 Scopus citations
2019

Pediatric-Onset Arrhythmogenic Cardiomyopathy: Look Right, Look Left, Look Both Ways

Ackerman, M. J. & Giudicessi, J. R., Jul 23 2019, In : Journal of the American College of Cardiology. 74, 3, p. 359-361 3 p.

Research output: Contribution to journalEditorial

Mothers with long QT syndrome are at increased risk for fetal death: findings from a multicenter international study

Fetal LQTS Consortium, Jan 1 2019, (Accepted/In press) In : American journal of obstetrics and gynecology.

Research output: Contribution to journalArticle