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  • Sundeep Khosla
2013

Estrogen Deficiency, Postmenopausal Osteoporosis, and Age-Related Bone Loss

Khosla, S. & Pacifici, R., Jun 2013, Osteoporosis: Fourth Edition. Elsevier Inc., p. 1113-1136 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Scopus citations
2011

Effects of physiological variations in circulating insulin levels on bone turnover in humans

Basu, R., Peterson, J., Rizza, R. & Khosla, S., May 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 5, p. 1450-1455 6 p.

Research output: Contribution to journalArticle

41 Scopus citations
2017

Clinical, cellular, microscopic, and ultrastructural studies of a case of fibrogenesis imperfecta ossium

Barron, M. L., Rybchyn, M. S., Ramesh, S., Mason, R. S., Fiona Bonar, S., Stalley, P., Khosla, S., Hudson, B., Arthur, C., Kim, E., Clifton-Bligh, R. J. & Clifton-Bligh, P. B., Mar 14 2017, In : Bone Research. 5, 16057.

Research output: Contribution to journalArticle

2 Scopus citations
2011

Is nitroglycerin a novel and inexpensive treatment for osteoporosis?

Khosla, S., Feb 23 2011, In : JAMA - Journal of the American Medical Association. 305, 8, p. 826-827 2 p.

Research output: Contribution to journalEditorial

15 Scopus citations
2013

Benefits and risks of bisphosphonate therapy for osteoporosis: Editorial comment

Khosla, S., Bilezikian, J. P., Dempster, D. W., Lewiecki, E. M., Miller, P. D., Neer, R. M., Recker, R. R., Shane, E., Shoback, D. & Potts, J. T., Jan 1 2013, In : Obstetrical and Gynecological Survey. 68, 1, p. 37-39 3 p.

Research output: Contribution to journalComment/debate

2014

Seeding Open Innovation Drug Discovery and Translational Collaborations to Leverage Government Funding: A Case Study of Strategic Partnership between Sanford-Burnham and Mayo Clinic

Chung, T. D. Y., Khosla, S., Badley, A. D. & Jackson, M. R., Apr 14 2014, Collaborative Innovation in Drug Discovery: Strategies for Public and Private Partnerships. Wiley Blackwell, p. 451-486 36 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
2019

Skeletal considerations in the medical treatment of transgender people

Khosla, S. & Davidge-Pitts, C., Dec 2019, In : The Lancet Diabetes and Endocrinology. 7, 12, p. 893-895 3 p.

Research output: Contribution to journalComment/debate

2012

Benefits and risks of bisphosphonate therapy for osteoporosis

Khosla, S., Bilezikian, J. P., Dempster, D. W., Lewiecki, E. M., Miller, P. D., Neer, R. M., Recker, R. R., Shane, E., Shoback, D. & Potts, J. T., Jul 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 7, p. 2272-2282 11 p.

Research output: Contribution to journalReview article

152 Scopus citations
2011

Fracture risk in men with prostate cancer: A population-based study

Melton, L. J., Lieber, M. M., Atkinson, E. J., Achenbach, S. J., Zincke, H., Therneau, T. M. & Khosla, S., Aug 1 2011, In : Journal of Bone and Mineral Research. 26, 8, p. 1808-1815 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2012

Relationship of femoral neck areal bone mineral density to volumetric bone mineral density, bone size, and femoral strength in men and women

Srinivasan, B., Kopperdahl, D. L., Amin, S., Atkinson, E. J., Camp, J., Robb, R. A., Riggs, B. L., Orwoll, E. S., Melton, L. J., Keaveny, T. M. & Khosla, S., Jan 1 2012, In : Osteoporosis International. 23, 1, p. 155-162 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2013

Improved fracture risk assessment based on nonlinear micro-finite element simulations from HRpQCT images at the distal radius

Christen, D., Melton, L. J., Zwahlen, A., Amin, S., Khosla, S. & Müller, R., Dec 1 2013, In : Journal of Bone and Mineral Research. 28, 12, p. 2601-2608 8 p.

Research output: Contribution to journalArticle

29 Scopus citations
2012

Emerging role of circulating calcifying cells in the bone-vascular axis

Fadini, G. P., Rattazzi, M., Matsumoto, T., Asahara, T. & Khosla, S., Jun 5 2012, In : Circulation. 125, 22, p. 2772-2781 10 p.

Research output: Contribution to journalArticle

59 Scopus citations
2013

Proximal femoral density distribution and structure in relation to age and hip fracture risk in women

Carballido-Gamio, J., Harnish, R., Saeed, I., Streeper, T., Sigurdsson, S., Amin, S., Atkinson, E. J., Therneau, T. M., Siggeirsdottir, K., Cheng, X., Melton, L. J., Keyak, J., Gudnason, V., Khosla, S., Harris, T. B. & Lang, T. F., Mar 1 2013, In : Journal of Bone and Mineral Research. 28, 3, p. 537-546 10 p.

Research output: Contribution to journalArticle

51 Scopus citations
2012

Relationship of age to bone microstructure independent of areal bone mineral density

Nicks, K. M., Amin, S., Atkinson, E. J., Riggs, B. L., Melton, L. J. & Khosla, S., Mar 1 2012, In : Journal of Bone and Mineral Research. 27, 3, p. 637-644 8 p.

Research output: Contribution to journalArticle

75 Scopus citations
2015

New Insights into Androgen and Estrogen Receptor Regulation of the Male Skeleton

Khosla, S., Jul 1 2015, In : Journal of Bone and Mineral Research. 30, 7, p. 1134-1137 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Clinical Use of Quantitative Computed Tomography-Based Advanced Techniques in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part III

Engelke, K., Lang, T., Khosla, S., Qin, L., Zysset, P., Leslie, W. D., Shepherd, J. A. & Shousboe, J. T., Jul 1 2015, In : Journal of Clinical Densitometry. 18, 3, p. 393-407 15 p.

Research output: Contribution to journalArticle

47 Scopus citations
2012

Insulin-mediated FFA suppression is associated with triglyceridemia and insulin sensitivity independent of adiposity

Bush, N. C., Basu, R., Rizza, R. A., Nair, K. S., Khosla, S. & Jensen, M. D., Nov 1 2012, In : Journal of Clinical Endocrinology and Metabolism. 97, 11, p. 4130-4138 9 p.

Research output: Contribution to journalArticle

12 Scopus citations
2011

Regulation of circulating sclerostin levels by sex steroids in women and in men

Mödder, U. I., Clowes, J. A., Hoey, K., Peterson, J. M., McCready, L., Oursler, M. J., Riggs, B. L. & Khosla, S., Jan 1 2011, In : Journal of Bone and Mineral Research. 26, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

155 Scopus citations

Corrigendum to "Circulating osteogenic cells: Characterization and relationship to rates of bone loss in postmenopausal women" [Bone 47 (2010) 83-92]

Undale, A., Srinivasan, B., Drake, M., McCready, L., Atkinson, E., Peterson, J., Riggs, B. L., Amin, S., Modder, U. I. & Khosla, S., Mar 1 2011, In : Bone. 48, 3, 1 p.

Research output: Contribution to journalComment/debate

2018

Regulation of bone metabolism by sex steroids

Khosla, S. & Monroe, D. G., Jan 1 2018, In : Cold Spring Harbor perspectives in medicine. 8, 1, a031211.

Research output: Contribution to journalReview article

27 Scopus citations
2011

Wnt10b activates the wnt, notch, and NFIκB pathways in u2os osteosarcoma cells

Mödder, U. I., Oursler, M. J., Khosla, S. & Monroe, D. G., May 1 2011, In : Journal of cellular biochemistry. 112, 5, p. 1392-1402 11 p.

Research output: Contribution to journalArticle

40 Scopus citations
2020

Aspirin and fracture risk: A systematic review and exploratory meta-analysis of observational studies

Barker, A. L., Soh, S. E., Sanders, K. M., Pasco, J., Khosla, S., Ebeling, P. R., Ward, S. A., Peeters, G., Talevski, J., Cumming, R. G., Seeman, E. & McNeil, J. J., Feb 20 2020, In : BMJ open. 10, 2, 026876.

Research output: Contribution to journalArticle

Open Access
2011

Towards a diagnostic and therapeutic consensus in male osteoporosis

Kanis, J. A., Bianchi, G., Bilezikian, J. P., Kaufman, J. M., Khosla, S., Orwoll, E. & Seeman, E., Nov 1 2011, In : Osteoporosis International. 22, 11, p. 2789-2798 10 p.

Research output: Contribution to journalArticle

87 Scopus citations
2012

Assessing fracture risk using gradient boosting machine (GBM) models

Atkinson, E. J., Therneau, T. M., Melton, L. J., Camp, J. J., Achenbach, S. J., Amin, S. & Khosla, S., Jun 1 2012, In : Journal of Bone and Mineral Research. 27, 6, p. 1397-1404 8 p.

Research output: Contribution to journalArticle

27 Scopus citations
67 Scopus citations
2011

Determinants of forearm strength in postmenopausal women

Melton, L. J., Riggs, B. L., Müller, R., Achenbach, S. J., Christen, D., Atkinson, E. J., Amin, S. & Khosla, S., Dec 1 2011, In : Osteoporosis International. 22, 12, p. 3047-3054 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
2013

Longitudinal changes in lumbar bone mineral density distribution may increase the risk of wedge fractures

Giambini, H., Khosla, S., Nassr, A., Zhao, C. & An, K. N., Jan 1 2013, In : Clinical Biomechanics. 28, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Pathogenesis of age-related bone loss in humans

Khosla, S., Oct 1 2013, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 68, 10, p. 1226-1235 10 p.

Research output: Contribution to journalArticle

102 Scopus citations
2014

Parathyroid Hormone in the Pathophysiology of Osteoporosis

Khosla, S., Sep 5 2014, The Parathyroids: Basic and Clinical Concepts: Third Edition. Elsevier Inc., p. 827-835 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Emerging therapeutic opportunities for skeletal restoration

Kawai, M., Mödder, U. I., Khosla, S. & Rosen, C. J., Feb 1 2011, In : Nature Reviews Drug Discovery. 10, 2, p. 141-156 16 p.

Research output: Contribution to journalReview article

89 Scopus citations
2014

Effects of estrogen on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in postmenopausal women

Fujita, K., Roforth, M. M., Demaray, S., McGregor, U., Kirmani, S., McCready, L. K., Peterson, J. M., Drake, M. T., Monroe, D. G. & Khosla, S., Jan 1 2014, In : Journal of Clinical Endocrinology and Metabolism. 99, 1, p. E81-E88

Research output: Contribution to journalArticle

36 Scopus citations
2017

Bone diseases: Romosozumab-on track or derailed?

Khosla, S., Dec 1 2017, In : Nature Reviews Endocrinology. 13, 12, p. 697-698 2 p.

Research output: Contribution to journalShort survey

11 Scopus citations
2011

The unitary model for estrogen deficiency and the pathogenesis of osteoporosis: Is a revision needed?

Khosla, S., Melton, L. J. & Riggs, B. L., Mar 1 2011, In : Journal of Bone and Mineral Research. 26, 3, p. 441-451 11 p.

Research output: Contribution to journalReview article

186 Scopus citations
2019

Sex-specific effects of dehydroepiandrosterone (DHEA) on bone mineral density and body composition: A pooled analysis of four clinical trials

Jankowski, C. M., Wolfe, P., Schmiege, S. J., Nair, K. S., Khosla, S., Jensen, M., von Muhlen, D., Laughlin, G. A., Kritz-Silverstein, D., Bergstrom, J., Bettencourt, R., Weiss, E. P., Villareal, D. T. & Kohrt, W. M., Feb 1 2019, In : Clinical Endocrinology. 90, 2, p. 293-300 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
2011

Forum on aging and skeletal health: Summary of the proceedings of an ASBMR workshop

Khosla, S., Bellido, T. M., Drezner, M. K., Gordon, C. M., Harris, T. B., Kiel, D. P., Kream, B. E., Leboff, M. S., Lian, J. B., Peterson, C. A., Rosen, C. J., Williams, J. P., Winer, K. K. & Sherman, S. S., Nov 1 2011, In : Journal of Bone and Mineral Research. 26, 11, p. 2565-2578 14 p.

Research output: Contribution to journalReview article

20 Scopus citations
2014

Validation of a CT-derived method for osteoporosis screening in IBD patients undergoing contrast-enhanced CT enterography

Weber, N. K., Fidler, J. L., Keaveny, T. M., Clarke, B. L., Khosla, S., Fletcher, J. G., Lee, D. C., Pardi, D. S., Loftus, E. V., Kane, S. V., Barlow, J. M., Murthy, N. S., Becker, B. D. & Bruining, D. H., Mar 2014, In : American Journal of Gastroenterology. 109, 3, p. 401-408 8 p.

Research output: Contribution to journalArticle

31 Scopus citations
2018

Factors associated with proximal femur fracture determined in a large cadaveric cohort

Dragomir Daescu, M. D., Rossman, T. L., Rezaei, A., Carlson, K. D., Kallmes, D. F., Skinner, J. A., Khosla, S. & Amin, S., Nov 1 2018, In : Bone. 116, p. 196-202 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
2019
1 Scopus citations

Estrogens and progestins

Monroe, D. G. & Khosla, S., Jan 1 2019, Principles of Bone Biology. Elsevier, p. 827-837 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2016

Operator variability in scan positioning is a major component of HR-pQCT precision error and is reduced by standardized training

Bonaretti, S., Vilayphiou, N., Chan, C. M., Yu, A., Nishiyama, K., Liu, D., Boutroy, S., Ghasem-Zadeh, A., Boyd, S. K., Chapurlat, R., McKay, H., Shane, E., Bouxsein, M. L., Black, D. M., Majumdar, S., Orwoll, E. S., Lang, T. F., Khosla, S. & Burghardt, A. J., Jul 30 2016, (Accepted/In press) In : Osteoporosis International. p. 1-13 13 p.

Research output: Contribution to journalArticle

15 Scopus citations

Technical note: Recommendations for a standard procedure to assess cortical bone at the tissue-level in vivo using impact microindentation

Diez-Perez, A., Bouxsein, M. L., Eriksen, E. F., Khosla, S., Nyman, J. S., Papapoulos, S. & Tang, S. Y., Dec 1 2016, In : Bone Reports. 5, p. 181-185 5 p.

Research output: Contribution to journalArticle

33 Scopus citations
2014

The clinical diagnosis of osteoporosis: A position statement from the National Bone Health Alliance Working Group

Siris, E. S., Adler, R., Bilezikian, J., Bolognese, M., Dawson-Hughes, B., Favus, M. J., Harris, S. T., Jan De Beur, S. M., Khosla, S., Lane, N. E., Lindsay, R., Nana, A. D., Orwoll, E. S., Saag, K., Silverman, S. & Watts, N. B., Jan 1 2014, In : Osteoporosis International. 25, 5, p. 1439-1443 5 p.

Research output: Contribution to journalArticle

201 Scopus citations
2011

Effects of intermittent parathyroid hormone treatment on osteoprogenitor cells in postmenopausal women

Drake, M. T., Srinivasan, B., Mödder, U. I., Ng, A. C., Undale, A. H., Roforth, M. M., Peterson, J. M., McCready, L. K., Riggs, B. L. & Khosla, S., Sep 1 2011, In : Bone. 49, 3, p. 349-355 7 p.

Research output: Contribution to journalArticle

32 Scopus citations
2014

Cortical porosity identifies women with osteopenia at increased risk for forearm fractures

Bala, Y., Zebaze, R., Ghasem-Zadeh, A., Atkinson, E. J., Iuliano, S., Peterson, J. M., Amin, S., Bjørnerem, Å., Melton, L. J., Johansson, H., Kanis, J. A., Khosla, S. & Seeman, E., Jun 2014, In : Journal of Bone and Mineral Research. 29, 6, p. 1356-1362 7 p.

Research output: Contribution to journalArticle

100 Scopus citations
2012

Male Osteoporosis

Drake, M. T. & Khosla, S., Sep 1 2012, In : Endocrinology and Metabolism Clinics of North America. 41, 3, p. 629-641 13 p.

Research output: Contribution to journalReview article

45 Scopus citations

Osteocalcin positive CD133+/CD34-/KDR+ progenitor cells as an independent marker for unstable atherosclerosis

Flammer, A. J., Gössl, M., Widmer, R. J., Reriani, M., Lennon, R., Loeffler, D., Shonyo, S., Simari, R. D., Lerman, L. O., Khosla, S. & Lerman, A., Dec 1 2012, In : European heart journal. 33, 23, p. 2963-2969 7 p.

Research output: Contribution to journalArticle

46 Scopus citations
2015

Osteogenic monocytes within the coronary circulation and their association with plaque vulnerability in patients with early atherosclerosis

Collin, J., Gössl, M., Matsuo, Y., Cilluffo, R. R., Flammer, A. J., Loeffler, D., Lennon, R. J., Simari, R. D., Spoon, D. B., Erbel, R., Lerman, L. O., Khosla, S. & Lerman, A., Feb 15 2015, In : International Journal of Cardiology. 181, p. 57-64 8 p.

Research output: Contribution to journalArticle

20 Scopus citations
2014

Coronary microvascular endothelial dysfunction is an independent predictor of development of osteoporosis in postmenopausal women

Prasad, M., Reriani, M., Khosla, S., Gössl, M., Lennon, R., Gulati, R., Prasad, A., Lerman, L. O. & Lerman, A., 2014, In : Vascular Health and Risk Management. 10, p. 533-538 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Diminished bone strength is observed in adult women and men who sustained a mild trauma distal forearm fracture during childhood

Farr, J. N., Khosla, S., Achenbach, S. J., Atkinson, E. J., Kirmani, S., McCready, L. K., Melton, L. J. & Amin, S., Oct 1 2014, In : Journal of Bone and Mineral Research. 29, 10, p. 2193-2202 10 p.

Research output: Contribution to journalArticle

13 Scopus citations
2013
25 Scopus citations