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  Tissue Transglutaminase and Its Product Isopeptide Are Increased in Alzheimer’s Disease and APPswe/PS1dE9 Double Transgenic Mice Brains

  Zhang, J., Wang, S., Huang, W., Bennett, D. A., Dickson, D. W., Wang, D. & Wang, R., Oct 1 2016, In: Molecular Neurobiology. 53, 8, p. 5066-5078 13 p.

  Research output: Contribution to journal › Article › peer-review
  14 Scopus citations

• Tissue translocation device for surgical correction of age-relatedmacular degeneration

  Mathai, G., Rosen, D., Melkote, S. & Olsen, T., Oct 10 2013, In: Journal of Medical Devices, Transactions of the ASME. 7, 4, p. 1-8 8 p.

  Research output: Contribution to journal › Article › peer-review

• Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis

  Benchenane, K., Berezowski, V., Ali, C., Fernández-Monreal, M., López-Atalaya, J. P., Brillault, J., Chuquet, J., Nouvelot, A., MacKenzie, E. T., Bu, G., Cecchelli, R., Touzani, O. & Vivien, D., May 3 2005, In: Circulation. 111, 17, p. 2241-2249 9 p.

  Research output: Contribution to journal › Article › peer-review
  145 Scopus citations

• Titanium Cervical Cage Subsidence: Postoperative Computed Tomography Analysis Defining Incidence and Associated Risk Factors

  Pinter, Z. W., Reed, R., Townsley, S. E., Mikula, A. L., Dittman, L., Xiong, A., Skjaerlund, J., Michalopoulos, G. D., Currier, B., Nassr, A., Fogelson, J. L., Freedman, B. A., Bydon, M., Kepler, C. K., Wagner, S. C., Elder, B. D. & Sebastian, A. S., 2021, (Accepted/In press) In: Global Spine Journal.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Titin isoforms, extracellular matrix, and global chamber remodeling in experimental dilated cardiomyopathy: functional implications and mechanistic insight.

  Jaber, W. A., Maniu, C., Krysiak, J., Shapiro, B. P., Meyer, D. M., Linke, W. A. & Redfield, M. M., Sep 2008, In: Circulation. Heart failure. 1, 3, p. 192-199 8 p.

  Research output: Contribution to journal › Article › peer-review
  25 Scopus citations

• Titration of feline immunodeficiency virus-based lentiviral vector preparations

  Saenz, D. T., Barraza, R., Loewen, N., Teo, W. & Poeschla, E. M., Jan 2012, In: Cold Spring Harbor Protocols. 7, 1, p. 126-128 3 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• Tizanidine treatment of spasticity caused by multiple sclerosis: Results of a double–blind, placebo–controlled trial

  US Tizanidine Study Group, Nov 1994, In: Neurology. 44, 11, p. S34-S42

  Research output: Contribution to journal › Article › peer-review
  114 Scopus citations

• Tizanidine Versus Baclofen in the Treatment of Spasticity in Patients with Multiple Sclerosis

  Bass, B., Weinshenker, B., Rice, G. P. A., Noseworthy, J. H., Cameron, M. G. P., Hader, W., Bouchard, S. & Ebers, G. C., Feb 1988, In: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 15, 1, p. 15-19 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  75 Scopus citations

• TL1A synergizes with IL-12 and IL-18 to enhance IFN-γ production in human T cells and NK cells

  Papadakis, K. A., Prehn, J. L., Landers, C., Han, Q., Luo, X., Cha, S. C., Wei, P. & Targan, S. R., Jun 1 2004, In: Journal of Immunology. 172, 11, p. 7002-7007 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  115 Scopus citations

• TLR3 activation evokes IL-6 secretion, autocrine regulation of Stat3 signaling and TLR2 expression in human bronchial epithelial cells

  Melkamu, T., Kita, H. & O'Grady, S. M., Jun 2013, In: Journal of Cell Communication and Signaling. 7, 2, p. 109-118 10 p.

  Research output: Contribution to journal › Article › peer-review
  19 Scopus citations

• TLR3 activation increases chemokine expression in human fetal airway smooth muscle cells

  Faksh, A., Britt, R. D., Vogel, E. R., Thompson, M. A., Pandya, H. C., Martin, R. J., Pabelick, C. M. & Prakash, Y. S., 2016, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 310, 2, p. L202-L211

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• TLR3 deficiency induces chronic inflammatory cardiomyopathy in resistant mice following coxsackievirus B3 infection: Role for IL-4

  Abston, E. D., Coronado, M. J., Bucek, A., Onyimba, J. A., Brandt, J. E., Augusto Frisancho, J., Kim, E., Bedja, D., Sung, Y. K., Radtke, A. J., Gabrielson, K. L., Mitzner, W. & Fairweather, D. L., Feb 15 2013, In: American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 304, 4, p. R267-R277

  Research output: Contribution to journal › Article › peer-review
  27 Scopus citations

• TLR3-driven IFN-β antagonizes STAT5-activating cytokines and suppresses innate type 2 response in the lung

  Tei, R., Iijima, K., Matsumoto, K., Kobayashi, T., Lama, J., Jacobsen, E. A. & Kita, H., Mar 2022, In: Journal of Allergy and Clinical Immunology. 149, 3, p. 1044-1059.e5

  Research output: Contribution to journal › Article › peer-review

• TLR3-stimulated dendritic cells up-regulate B7-H1 expression and influence the magnitude of CD8 T cell responses to tumor vaccination

  Pulko, V., Liu, X., Krco, C. J., Harris, K. J., Frigola, X., Kwon, E. D. & Dong, H., Sep 15 2009, In: Journal of Immunology. 183, 6, p. 3634-3641 8 p.

  Research output: Contribution to journal › Article › peer-review
  76 Scopus citations

• TLR4 promotes cryptosporidium parvum clearance in a mouse model of biliary cryptosporidiosis

  O'Hara, S. P., Tietz Bogert, P. S., Trussoni, C. E., Chen, X. & Larusso, N. F., Oct 2011, In: Journal of Parasitology. 97, 5, p. 813-821 9 p.

  Research output: Contribution to journal › Article › peer-review
  23 Scopus citations

• TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease

  Chakrabarty, P., Li, A., Ladd, T. B., Strickland, M. R., Koller, E. J., Burgess, J. D., Funk, C. C., Cruz, P. E., Allen, M., Yaroshenko, M., Wang, X., Younkin, C., Reddy, J., Lohrer, B., Mehrke, L., Moore, B. D., Liu, X., Ceballos‑Diaz, C., Rosario, A. M., Medway, C. & 8 others, Janus, C., Li, H. D., Dickson, D. W., Giasson, B. I., Price, N. D., Younkin, S. G., Ertekin‑Taner, N. & Golde, T. E., 2018, In: Journal of Experimental Medicine. 215, 9, p. 2247-2264 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  17 Scopus citations

• TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development

  Sun, J., Walsh, M., Villarino, A. V., Cervi, L., Hunter, C. A., Choi, Y. & Pearce, E. J., Jan 15 2005, In: Journal of Immunology. 174, 2, p. 742-751 10 p.

  Research output: Contribution to journal › Article › peer-review
  71 Scopus citations

• TLR-mediated induction of negative regulatory ligands on dendritic cells

  Gröschel, S., Piggott, K. D., Vaglio, A., Ma-Krupa, W., Singh, K., Goronzy, J. J. & Weyand, C. M., Apr 2008, In: Journal of Molecular Medicine. 86, 4, p. 443-455 13 p.

  Research output: Contribution to journal › Article › peer-review
  28 Scopus citations

• TLR stimulation modifies BLyS receptor expression in follicular and marginal zone B cells

  Treml, L. S., Carlesso, G., Hoek, K. L., Stadanlick, J. E., Kambayashi, T., Bram, R. J., Cancro, M. P. & Khan, W. N., Jun 15 2007, In: Journal of Immunology. 178, 12, p. 7531-7539 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  116 Scopus citations

• TLX3 repressed snai1-induced epithelial-mesenchymal transition by directly constraining STAT3 phosphorylation and functionally sensitized 5-FU chemotherapy in hepatocellular carcinoma

  Wang, C., Dou, C., Wang, Y., Liu, Z., Roberts, L. & Zheng, X., 2019, In: International Journal of Biological Sciences. 15, 8, p. 1696-1711 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• T lymphocyte enriched murine peritoneal exudate cells. III. Inhibition of antigen induced T lymphocyte proliferation with anti Ia antisera

  Schwartz, R. H., David, C. S., Sachs, D. H. & Paul, W. E., Dec 1 1976, In: Journal of Immunology. 117, 2, p. 531-540 10 p.

  Research output: Contribution to journal › Article › peer-review
  102 Scopus citations

• T lymphocyte responses to non-H-2 histocompatibility antigens. I. Role of Ly-1⁺2⁺ T cells as cytotoxic effectors and requirement for Ly-1⁺2⁺ T cells for optimal generation of cytotoxic effectors

  Wettstein, P. J. & Frelinger, J. A., 1981, In: Journal of Immunology. 127, 1, p. 43-46 4 p.

  Research output: Contribution to journal › Article › peer-review
  6 Scopus citations

• T lymphocyte response to H-2 mutants: Cytotoxic effectors are Ly-1 ⁺2 ⁺

  Wettstein, P. J., Bailey, D. W., Mobraaten, L. E., Klein, J. & Frelinger, J. A., 1979, In: Proceedings of the National Academy of Sciences of the United States of America. 76, 7, p. 3455-3459 5 p.

  Research output: Contribution to journal › Article › peer-review
  36 Scopus citations

• T-lymphocyte response to H-2 mutants: I. Proliferation is dependent on Ly 1⁺2⁺ cells*

  Wettstein, P. J., Bailey, D. W., Mobraaten, L. E., Klein, J. & Frelinger, J. A., May 1 1978, In: Journal of Experimental Medicine. 147, 5, p. 1395-1404 10 p.

  Research output: Contribution to journal › Article › peer-review
  35 Scopus citations

• T-lymphocyte subsets in patients with idiopathic dilated cardiomyopathy

  Huber, K. C., Gersh, B. J., Sugrue, D. D., Frye, R. L., Bailey, K. R. & Ritts, R. E., Jan 1989, In: International Journal of Cardiology. 22, 1, p. 59-66 8 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• TMEM106B and myelination: Rare leukodystrophy families reveal unexpected connections

  Zhou, X. & Rademakers, R., Dec 1 2017, In: Brain. 140, 12, p. 3069-3072 4 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• TMEM106B haplotypes have distinct gene expression patterns in aged brain

  Ren, Y., Van Blitterswijk, M., Allen, M., Carrasquillo, M. M., Reddy, J. S., Wang, X., Beach, T. G., Dickson, D. W., Ertekin-Taner, N., Asmann, Y. W. & Rademakers, R., Jul 3 2018, In: Molecular neurodegeneration. 13, 1, 35.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  12 Scopus citations

• TMEM106B p.T185S regulates TMEM106B protein levels: Implications for frontotemporal dementia

  Nicholson, A. M., Finch, N. A., Wojtas, A., Baker, M. C., Perkerson, R. B., Castanedes-Casey, M., Rousseau, L., Benussi, L., Binetti, G., Ghidoni, R., Hsiung, G. Y. R., Mackenzie, I. R., Finger, E., Boeve, B. F., Ertekin-Taner, N., Graff-Radford, N. R., Dickson, D. W. & Rademakers, R., Sep 2013, In: Journal of neurochemistry. 126, 6, p. 781-791 11 p.

  Research output: Contribution to journal › Article › peer-review
  53 Scopus citations

• TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia

  Van Blitterswijk, M., Mullen, B., Nicholson, A. M., Bieniek, K. F., Heckman, M. G., Baker, M. C., Dejesus-Hernandez, M., Finch, N. A., Brown, P. H., Murray, M. E., Hsiung, G. Y. R., Stewart, H., Karydas, A. M., Finger, E., Kertesz, A., Bigio, E. H., Weintraub, S., Mesulam, M., Hatanpaa, K. J., White, C. L. & 19 others, Strong, M. J., Beach, T. G., Wszolek, Z. K., Lippa, C., Caselli, R., Petrucelli, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Mackenzie, I. R., Seeley, W. W., Grinberg, L. T., Miller, B. L., Boylan, K. B., Graff-Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R., Mar 2014, In: Acta neuropathologica. 127, 3, p. 397-406 10 p.

  Research output: Contribution to journal › Article › peer-review
  95 Scopus citations

• TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers

  Finch, N., Carrasquillo, M. M., Baker, M., Rutherford, N. J., Coppola, G., Dejesus-Hernandez, M., Crook, R., Hunter, T., Ghidoni, R., Benussi, L., Crook, J., Finger, E., Hantanpaa, K. J., Karydas, A. M., Sengdy, P., Gonzalez, J., Seeley, W. W., Johnson, N., Beach, T. G., Mesulam, M. & 19 others, Forloni, G., Kertesz, A., Knopman, D. S., Uitti, R., White, C. L., Caselli, R., Lippa, C., Bigio, E. H., Wszolek, Z. K., Binetti, G., MacKenzie, I. R., Miller, B. L., Boeve, B. F., Younkin, S. G., Dickson, D. W., Petersen, R. C., Graff-Radford, N. R., Geschwind, D. H. & Rademakers, R., Feb 1 2011, In: Neurology. 76, 5, p. 467-474 8 p.

  Research output: Contribution to journal › Article › peer-review
  157 Scopus citations

• Tmem16A encodes the Ca²⁺-activated Cl^- channel in mouse submandibular salivary gland acinar cells

  Romanenko, V. G., Catalán, M. A., Brown, D. A., Putzier, I., Hartzell, H. C., Marmorstein, A. D., Gonzalez-Begne, M., Rock, J. R., Harfe, B. D. & Melvin, J. E., Apr 23 2010, In: Journal of Biological Chemistry. 285, 17, p. 12990-13001 12 p.

  Research output: Contribution to journal › Article › peer-review
  141 Scopus citations

• TMEM199 Deficiency is a Disorder of Golgi Homeostasis Characterized by Elevated Aminotransferases, Alkaline Phosphatase, and Cholesterol and Abnormal Glycosylation

  Jansen, J. C., Timal, S., Van Scherpenzeel, M., Michelakakis, H., Vicogne, D., Ashikov, A., Moraitou, M., Hoischen, A., Huijben, K., Steenbergen, G., Van Den Boogert, M. A. W., Porta, F., Calvo, P. L., Mavrikou, M., Cenacchi, G., Van Den Bogaart, G., Salomon, J., Holleboom, A. G., Rodenburg, R. J., Drenth, J. P. H. & 6 others, Huynen, M. A., Wevers, R. A., Morava, E., Foulquier, F., Veltman, J. A. & Lefeber, D. J., Feb 4 2016, In: American journal of human genetics. 98, 2, p. 322-330 9 p.

  Research output: Contribution to journal › Article › peer-review
  37 Scopus citations

• TMEM70 deficiency: long-term outcome of 48 patients

  Magner, M., Dvorakova, V., Tesarova, M., Mazurova, S., Hansikova, H., Zahorec, M., Brennerova, K., Bzduch, V., Spiegel, R., Horovitz, Y., Mandel, H., Eminoğlu, F. T., Mayr, J. A., Koch, J., Martinelli, D., Bertini, E., Konstantopoulou, V., Smet, J., Rahman, S., Broomfield, A. & 7 others, Stojanović, V., Dionisi-Vici, C., van Coster, R., Morava-Kozicz, E., Sperl, W., Zeman, J. & Honzik, T., May 16 2015, In: Journal of inherited metabolic disease. 38, 3, p. 417-426 10 p.

  Research output: Contribution to journal › Article › peer-review
  33 Scopus citations

• TMPrSS2-ERG controls luminal epithelial lineage and antiandrogen sensitivity in PTEN and TP53-mutated prostate cancer

  Blee, A. M., He, Y., Yang, Y., Ye, Z., Yan, Y., Pan, Y., Ma, T., Dugdale, J., Kuehn, E., Kohli, M., Jimenez, R., Chen, Y., Xu, W., Wang, L. & Huang, H., Sep 15 2018, In: Clinical Cancer Research. 24, 18, p. 4551-4565 15 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• TMT-Based Multiplexed Quantitation of N-Glycopeptides Reveals Glycoproteome Remodeling Induced by Oncogenic Mutations

  Saraswat, M., Mangalaparthi, K. K., Garapati, K. & Pandey, A., Apr 5 2022, In: ACS Omega. 7, 13, p. 11023-11032 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• TNFa induces mitochondrial fragmentation and biogenesis in human airway smooth muscle

  Delmotte, P., Mathieu, N. M. & Sieck, G. C., 2021, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 320, 1, p. L137-L151

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• TNF-Alpha Inhibition and Other Immunosuppressants in the Development of Uveal and Cutaneous Melanoma

  Damento, G. M., Pulido, J. S., Abbott, B. A., Hodge, D. O. & Dalvin, L. A., Jul 2019, In: Mayo Clinic proceedings. 94, 7, p. 1287-1295 9 p.

  Research output: Contribution to journal › Article › peer-review
  3 Scopus citations

• TNF down-regulation of receptor tyrosine kinase-dependent mitogenic signal pathways as an important step in cytostasis induction and commitment to apoptosis of Kym-1 rhabdomyosarcoma cells

  Storz, P., Doppler, H., Horn-Muller, J., Muller, G. & Pfizenmaier, K., 2000, In: Cell Death and Differentiation. 7, 10, p. 955-965 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  11 Scopus citations

• TNF inhibitors and infections

  Orenstein, R. & Matteson, E. L., Mar 1 2006, In: Infections in Medicine. 23, 3, p. 99-114 16 p.

  Research output: Contribution to journal › Article › peer-review
  2 Scopus citations

• TNF inhibits insulin induced STAT5 activation in differentiated mouse muscle cells pmi28

  Storz, P., Döppler, H., Wernig, A., Pfizenmaier, K. & Müller, G., Nov 27 1998, In: FEBS Letters. 440, 1-2, p. 41-45 5 p.

  Research output: Contribution to journal › Article › peer-review
  30 Scopus citations

• TNF receptor I is required for induction of macrophage heat shock protein 70

  Heimbach, J. K., Reznikov, L. L., Calkins, C. M., Robinson, T. N., Dinarello, C. A., Harken, A. H. & Meng, X., 2001, In: American Journal of Physiology - Cell Physiology. 281, 1 50-1, p. C241-C247

  Research output: Contribution to journal › Article › peer-review
  14 Scopus citations

• TNF receptor I mediates chemokine production and neutrophil accumulation in the lung following systemic lipopolysaccharide

  Calkins, C. M., Heimbach, J. K., Bensard, D. D., Song, Y., Raeburn, C. D., Meng, X. & McIntyre, R. C., 2001, In: Journal of Surgical Research. 101, 2, p. 232-237 6 p.

  Research output: Contribution to journal › Article › peer-review
  36 Scopus citations

• TNFRSF13B genotypes control immune-mediated pathology by regulating the functions of innate B cells

  De Mattos Barbosa, M. G., Lefferts, A. R., Huynh, D., Liu, H., Zhang, Y., Fu, B., Barnes, J., Samaniego, M., Bram, R. J., Geha, R. S., Shikanov, A., Luning Prak, E. T., Farkash, E. A., Platt, J. L. & Cascalho, M., Sep 8 2021, In: JCI Insight. 6, 17, e150483.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• TNFRSF13B polymorphisms counter microbial adaptation to enteric IgA

  Platt, J. L., de Mattos Barbosa, M. G., Huynh, D., Lefferts, A. R., Katta, J., Kharas, C., Freddolino, P., Bassis, C. M., Wobus, C., Geha, R., Bram, R., Nunez, G., Kamada, N. & Cascalho, M., Jul 22 2021, In: JCI Insight. 6, 14, e148208.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• TNF-selectively activates the IRE1-/XBP1 endoplasmic reticulum stress pathway in human airway smooth muscle cells

  Yap, J., Chen, X., Delmotte, P., Sieck, G. C. & Sieck, G. C., Mar 2020, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 318, 3, p. L483-L493

  Research output: Contribution to journal › Article › peer-review

  Open Access
  8 Scopus citations

• TNFα and IL-1β influence the differentiation and migration of murine MSCs independently of the NF-κB pathway

  Sullivan, C. B., Porter, R. M., Evans, C. H., Ritter, T., Shaw, G., Barry, F. & Murphy, J. M., Aug 27 2014, In: Stem Cell Research and Therapy. 5, 4, 104.

  Research output: Contribution to journal › Article › peer-review
  40 Scopus citations

• TNF-α-converting enzyme/A disintegrin and metalloprotease - 17 mediates mechanotransduction in murine tracheal epithelial cells

  Shiomi, T., Tschumperlin, D. J., Park, J. A., Sunnarborg, S. W., Horiuchi, K., Blobel, C. P. & Drazen, J. M., Aug 1 2011, In: American journal of respiratory cell and molecular biology. 45, 2, p. 376-385 10 p.

  Research output: Contribution to journal › Article › peer-review
  19 Scopus citations

• TNFα decreases mitochondrial movement in human airway smooth muscle

  Delmotte, P., Zavaletta, V. A., Thompson, M. A., Prakash, Y. S. & Sieck, G. C., 2017, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 313, 1, p. L166-L176

  Research output: Contribution to journal › Article › peer-review
  11 Scopus citations

• TNF-α differentially regulates synaptic plasticity in the hippocampus and spinal cord by microglia-dependent mechanisms after peripheral nerve injury

  Liu, Y., Zhou, L. J., Wang, J., Li, D., Ren, W. J., Peng, J., Wei, X., Xu, T., Xin, W. J., Pang, R. P., Li, Y. Y., Qin, Z. H., Murugan, M., Mattson, M. P., Wu, L. J. & Liu, X. G., Jan 25 2017, In: Journal of Neuroscience. 37, 4, p. 871-881 11 p.

  Research output: Contribution to journal › Article › peer-review
  108 Scopus citations

• TNFα enhances force generation in airway smooth muscle

  Dogan, M., Han, Y. S., Delmotte, P. & Sieck, G. C., Jun 5 2017, In: American Journal of Physiology - Lung Cellular and Molecular Physiology. 312, 6, p. L994-L1002

  Research output: Contribution to journal › Article › peer-review
  12 Scopus citations