Abstract
Regional heart wall dynamics has been shown to be a sensitive indicator of LV wall ischemia. Rates of local LV wall thickening during a cardiac cycle can be measured and illustrated using functional parametric mappings. This display conveys the spatial distribution of dynamic strain in the myocardium and thereby provides a rapid qualitative appreciation of the severity and extent of the ischemic region. 3D reconstructions were obtained in an anesthetized pig from 8 adjacent, shortaxis, slices of the left ventricle imaged with an Electron Beato Computer Tomograph at 11 time points through one complete cardiac cycle. The 3D reconstructions were obtained before and after injection of 100 μm microspheres into the Left Anterior Descending (LAD) coronary artery. This injection causes microembolization of LAD artery branches within the heart wall. The image processing involved radially dividing the tomographic images of the myocardium into small subdivisions with color encoding of the local magnitude of regional thickness or regional velocities of LV wall thickening throughout the cardiac cycle. We compared the effectiveness of animation of wall thickness encoded in color versus a static image of computed rate of wall thickness change in color. The location, extent and severity of regional wall akinesis or dyskinesis, as determined from these displays, can then be compared to the region of embolization as indicated by the distribution of altered LV wall perfusion.
| Original language | English (US) |
|---|---|
| Title of host publication | Proceedings of SPIE - The International Society for Optical Engineering |
| Editors | C. Chen, A.V. Clough |
| Pages | 100-107 |
| Number of pages | 8 |
| Volume | 4321 |
| DOIs | |
| State | Published - 2001 |
| Event | Medical Imaging 2001: Physiology and Function from Multidimensional Images - Sandiego, CA, United States Duration: Feb 18 2001 → Feb 20 2001 |
Other
| Other | Medical Imaging 2001: Physiology and Function from Multidimensional Images |
|---|---|
| Country | United States |
| City | Sandiego, CA |
| Period | 2/18/01 → 2/20/01 |
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Keywords
- Cardiac dynamics
- Coronary microembolism
- Functional mapping
- Local heart motion Analysis
- LV wall perfusion
- LV wall thickening
ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Condensed Matter Physics
Cite this
3D quantitative visualization of altered LV wall thickening dynamics caused by coronary microembolization. / Eusemann, C. D.; Mohlenkamp, S.; Ritman, E. L.; Robb, R. A.
Proceedings of SPIE - The International Society for Optical Engineering. ed. / C. Chen; A.V. Clough. Vol. 4321 2001. p. 100-107.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - 3D quantitative visualization of altered LV wall thickening dynamics caused by coronary microembolization
AU - Eusemann, C. D.
AU - Mohlenkamp, S.
AU - Ritman, E. L.
AU - Robb, R. A.
PY - 2001
Y1 - 2001
N2 - Regional heart wall dynamics has been shown to be a sensitive indicator of LV wall ischemia. Rates of local LV wall thickening during a cardiac cycle can be measured and illustrated using functional parametric mappings. This display conveys the spatial distribution of dynamic strain in the myocardium and thereby provides a rapid qualitative appreciation of the severity and extent of the ischemic region. 3D reconstructions were obtained in an anesthetized pig from 8 adjacent, shortaxis, slices of the left ventricle imaged with an Electron Beato Computer Tomograph at 11 time points through one complete cardiac cycle. The 3D reconstructions were obtained before and after injection of 100 μm microspheres into the Left Anterior Descending (LAD) coronary artery. This injection causes microembolization of LAD artery branches within the heart wall. The image processing involved radially dividing the tomographic images of the myocardium into small subdivisions with color encoding of the local magnitude of regional thickness or regional velocities of LV wall thickening throughout the cardiac cycle. We compared the effectiveness of animation of wall thickness encoded in color versus a static image of computed rate of wall thickness change in color. The location, extent and severity of regional wall akinesis or dyskinesis, as determined from these displays, can then be compared to the region of embolization as indicated by the distribution of altered LV wall perfusion.
AB - Regional heart wall dynamics has been shown to be a sensitive indicator of LV wall ischemia. Rates of local LV wall thickening during a cardiac cycle can be measured and illustrated using functional parametric mappings. This display conveys the spatial distribution of dynamic strain in the myocardium and thereby provides a rapid qualitative appreciation of the severity and extent of the ischemic region. 3D reconstructions were obtained in an anesthetized pig from 8 adjacent, shortaxis, slices of the left ventricle imaged with an Electron Beato Computer Tomograph at 11 time points through one complete cardiac cycle. The 3D reconstructions were obtained before and after injection of 100 μm microspheres into the Left Anterior Descending (LAD) coronary artery. This injection causes microembolization of LAD artery branches within the heart wall. The image processing involved radially dividing the tomographic images of the myocardium into small subdivisions with color encoding of the local magnitude of regional thickness or regional velocities of LV wall thickening throughout the cardiac cycle. We compared the effectiveness of animation of wall thickness encoded in color versus a static image of computed rate of wall thickness change in color. The location, extent and severity of regional wall akinesis or dyskinesis, as determined from these displays, can then be compared to the region of embolization as indicated by the distribution of altered LV wall perfusion.
KW - Cardiac dynamics
KW - Coronary microembolism
KW - Functional mapping
KW - Local heart motion Analysis
KW - LV wall perfusion
KW - LV wall thickening
UR - http://www.scopus.com/inward/record.url?scp=0034866638&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034866638&partnerID=8YFLogxK
U2 - 10.1117/12.428125
DO - 10.1117/12.428125
M3 - Conference contribution
AN - SCOPUS:0034866638
VL - 4321
SP - 100
EP - 107
BT - Proceedings of SPIE - The International Society for Optical Engineering
A2 - Chen, C.
A2 - Clough, A.V.
ER -