3D morphological analysis of lung pathology

Vanessa A. Zavaletta, Brian J. Bartholmai, Richard A. Robb

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Normal pulmonary function relies upon the configuration of the microscopic and macroscopic structural components of the lungs. The 3-dimensional microscopic lung structure is clearly apparent through techniques such as micro-CT, but in-vivo examination of human lungs cannot be examined on micro-CT. However, the near microscopic structure of the lungs can be visualized through volumetric high-resolution computed tomography (CT) on modern multidetector scanner at isotropic resolution of less than a millimeter. The properties of these near-microscopic structures of the lung can be analyzed through image processing algorithms, and alterations in these structures due to pulmonary disease can be detected and quantified through use of these same algorithms. For example, the changes visually apparent in idiopathic pulmonary fibrosis (IPF)-a disease in which normal lung is distorted and replaced by fibrous tissue and abnormal air spaces-can be detected and quantified through morphological analysis.

Original languageEnglish (US)
Title of host publication2007 4th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro - Proceedings
Pages308-311
Number of pages4
DOIs
StatePublished - Nov 27 2007
Event2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07 - Arlington, VA, United States
Duration: Apr 12 2007Apr 15 2007

Publication series

Name2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings

Other

Other2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro; ISBI'07
CountryUnited States
CityArlington, VA
Period4/12/074/15/07

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Medicine(all)

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    Zavaletta, V. A., Bartholmai, B. J., & Robb, R. A. (2007). 3D morphological analysis of lung pathology. In 2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings (pp. 308-311). [4193284] (2007 4th IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Proceedings). https://doi.org/10.1109/ISBI.2007.356850