2015 Recommendations for the Management of Polymyalgia Rheumatica: A European League Against Rheumatism/American College of Rheumatology Collaborative Initiative

Christian Dejaco, Yogesh P. Singh, Pablo Perel, Andrew Hutchings, Dario Camellino, Sarah Mackie, Andy Abril, Artur Bachta, Peter Balint, Kevin Barraclough, Lina Bianconi, Frank Buttgereit, Steven Carsons, Daniel Ching, Maria Cid, Marco Cimmino, Andreas Diamantopoulos, William Docken, Christina Duftner, Billy FashanuKate Gilbert, Pamela Hildreth, Jane Hollywood, David Jayne, Manuella Lima, Ajesh Maharaj, Christian Mallen, Victor Martinez-Taboada, Mehrdad Maz, Steven Merry, Jean Miller, Shunsuke Mori, Lorna Neill, Elisabeth Nordborg, Jennifer Nott, Hannah Padbury, Colin Pease, Carlo Salvarani, Michael Schirmer, Wolfgang Schmidt, Robert Spiera, David Tronnier, Alexandre Wagner, Madeline Whitlock, Eric Lawrence Matteson, Bhaskar Dasgupta

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations for PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) recommendations for the management of PMR. We used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology as a framework for the project. Accordingly, the direction and strength of the recommendations are based on the quality of evidence, the balance between desirable and undesirable effects, patients' and clinicians' values and preferences, and resource use. Eight overarching principles and nine specific recommendations were developed covering several aspects of PMR, including basic and follow-up investigations of patients under treatment, risk factor assessment, medical access for patients and specialist referral, treatment strategies such as initial glucocorticoid (GC) doses and subsequent tapering regimens, use of intramuscular GCs and disease modifying anti-rheumatic drugs (DMARDs), as well as the roles of non-steroidal anti-rheumatic drugs and non-pharmacological interventions. These recommendations will inform primary, secondary and tertiary care physicians about an international consensus on the management of PMR. These recommendations should serve to inform clinicians about best practices in the care of patients with PMR.

Original languageEnglish (US)
Pages (from-to)2569-2580
Number of pages12
JournalArthritis and Rheumatology
Volume67
Issue number10
DOIs
StatePublished - Oct 1 2015

Fingerprint

Polymyalgia Rheumatica
Antirheumatic Agents
Secondary Care
Tertiary Healthcare
Therapeutics
Practice Guidelines
Glucocorticoids
Primary Health Care
Patient Care
Referral and Consultation
Physicians

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Rheumatology

Cite this

2015 Recommendations for the Management of Polymyalgia Rheumatica : A European League Against Rheumatism/American College of Rheumatology Collaborative Initiative. / Dejaco, Christian; Singh, Yogesh P.; Perel, Pablo; Hutchings, Andrew; Camellino, Dario; Mackie, Sarah; Abril, Andy; Bachta, Artur; Balint, Peter; Barraclough, Kevin; Bianconi, Lina; Buttgereit, Frank; Carsons, Steven; Ching, Daniel; Cid, Maria; Cimmino, Marco; Diamantopoulos, Andreas; Docken, William; Duftner, Christina; Fashanu, Billy; Gilbert, Kate; Hildreth, Pamela; Hollywood, Jane; Jayne, David; Lima, Manuella; Maharaj, Ajesh; Mallen, Christian; Martinez-Taboada, Victor; Maz, Mehrdad; Merry, Steven; Miller, Jean; Mori, Shunsuke; Neill, Lorna; Nordborg, Elisabeth; Nott, Jennifer; Padbury, Hannah; Pease, Colin; Salvarani, Carlo; Schirmer, Michael; Schmidt, Wolfgang; Spiera, Robert; Tronnier, David; Wagner, Alexandre; Whitlock, Madeline; Matteson, Eric Lawrence; Dasgupta, Bhaskar.

In: Arthritis and Rheumatology, Vol. 67, No. 10, 01.10.2015, p. 2569-2580.

Research output: Contribution to journalArticle

Dejaco, C, Singh, YP, Perel, P, Hutchings, A, Camellino, D, Mackie, S, Abril, A, Bachta, A, Balint, P, Barraclough, K, Bianconi, L, Buttgereit, F, Carsons, S, Ching, D, Cid, M, Cimmino, M, Diamantopoulos, A, Docken, W, Duftner, C, Fashanu, B, Gilbert, K, Hildreth, P, Hollywood, J, Jayne, D, Lima, M, Maharaj, A, Mallen, C, Martinez-Taboada, V, Maz, M, Merry, S, Miller, J, Mori, S, Neill, L, Nordborg, E, Nott, J, Padbury, H, Pease, C, Salvarani, C, Schirmer, M, Schmidt, W, Spiera, R, Tronnier, D, Wagner, A, Whitlock, M, Matteson, EL & Dasgupta, B 2015, '2015 Recommendations for the Management of Polymyalgia Rheumatica: A European League Against Rheumatism/American College of Rheumatology Collaborative Initiative', Arthritis and Rheumatology, vol. 67, no. 10, pp. 2569-2580. https://doi.org/10.1002/art.39333
Dejaco, Christian ; Singh, Yogesh P. ; Perel, Pablo ; Hutchings, Andrew ; Camellino, Dario ; Mackie, Sarah ; Abril, Andy ; Bachta, Artur ; Balint, Peter ; Barraclough, Kevin ; Bianconi, Lina ; Buttgereit, Frank ; Carsons, Steven ; Ching, Daniel ; Cid, Maria ; Cimmino, Marco ; Diamantopoulos, Andreas ; Docken, William ; Duftner, Christina ; Fashanu, Billy ; Gilbert, Kate ; Hildreth, Pamela ; Hollywood, Jane ; Jayne, David ; Lima, Manuella ; Maharaj, Ajesh ; Mallen, Christian ; Martinez-Taboada, Victor ; Maz, Mehrdad ; Merry, Steven ; Miller, Jean ; Mori, Shunsuke ; Neill, Lorna ; Nordborg, Elisabeth ; Nott, Jennifer ; Padbury, Hannah ; Pease, Colin ; Salvarani, Carlo ; Schirmer, Michael ; Schmidt, Wolfgang ; Spiera, Robert ; Tronnier, David ; Wagner, Alexandre ; Whitlock, Madeline ; Matteson, Eric Lawrence ; Dasgupta, Bhaskar. / 2015 Recommendations for the Management of Polymyalgia Rheumatica : A European League Against Rheumatism/American College of Rheumatology Collaborative Initiative. In: Arthritis and Rheumatology. 2015 ; Vol. 67, No. 10. pp. 2569-2580.
@article{4f769a50c7b14fbbb45c55e4f5b393ec,
title = "2015 Recommendations for the Management of Polymyalgia Rheumatica: A European League Against Rheumatism/American College of Rheumatology Collaborative Initiative",
abstract = "Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations for PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) recommendations for the management of PMR. We used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology as a framework for the project. Accordingly, the direction and strength of the recommendations are based on the quality of evidence, the balance between desirable and undesirable effects, patients' and clinicians' values and preferences, and resource use. Eight overarching principles and nine specific recommendations were developed covering several aspects of PMR, including basic and follow-up investigations of patients under treatment, risk factor assessment, medical access for patients and specialist referral, treatment strategies such as initial glucocorticoid (GC) doses and subsequent tapering regimens, use of intramuscular GCs and disease modifying anti-rheumatic drugs (DMARDs), as well as the roles of non-steroidal anti-rheumatic drugs and non-pharmacological interventions. These recommendations will inform primary, secondary and tertiary care physicians about an international consensus on the management of PMR. These recommendations should serve to inform clinicians about best practices in the care of patients with PMR.",
author = "Christian Dejaco and Singh, {Yogesh P.} and Pablo Perel and Andrew Hutchings and Dario Camellino and Sarah Mackie and Andy Abril and Artur Bachta and Peter Balint and Kevin Barraclough and Lina Bianconi and Frank Buttgereit and Steven Carsons and Daniel Ching and Maria Cid and Marco Cimmino and Andreas Diamantopoulos and William Docken and Christina Duftner and Billy Fashanu and Kate Gilbert and Pamela Hildreth and Jane Hollywood and David Jayne and Manuella Lima and Ajesh Maharaj and Christian Mallen and Victor Martinez-Taboada and Mehrdad Maz and Steven Merry and Jean Miller and Shunsuke Mori and Lorna Neill and Elisabeth Nordborg and Jennifer Nott and Hannah Padbury and Colin Pease and Carlo Salvarani and Michael Schirmer and Wolfgang Schmidt and Robert Spiera and David Tronnier and Alexandre Wagner and Madeline Whitlock and Matteson, {Eric Lawrence} and Bhaskar Dasgupta",
year = "2015",
month = "10",
day = "1",
doi = "10.1002/art.39333",
language = "English (US)",
volume = "67",
pages = "2569--2580",
journal = "Arthritis and Rheumatology",
issn = "2326-5191",
publisher = "John Wiley and Sons Ltd",
number = "10",

}

TY - JOUR

T1 - 2015 Recommendations for the Management of Polymyalgia Rheumatica

T2 - A European League Against Rheumatism/American College of Rheumatology Collaborative Initiative

AU - Dejaco, Christian

AU - Singh, Yogesh P.

AU - Perel, Pablo

AU - Hutchings, Andrew

AU - Camellino, Dario

AU - Mackie, Sarah

AU - Abril, Andy

AU - Bachta, Artur

AU - Balint, Peter

AU - Barraclough, Kevin

AU - Bianconi, Lina

AU - Buttgereit, Frank

AU - Carsons, Steven

AU - Ching, Daniel

AU - Cid, Maria

AU - Cimmino, Marco

AU - Diamantopoulos, Andreas

AU - Docken, William

AU - Duftner, Christina

AU - Fashanu, Billy

AU - Gilbert, Kate

AU - Hildreth, Pamela

AU - Hollywood, Jane

AU - Jayne, David

AU - Lima, Manuella

AU - Maharaj, Ajesh

AU - Mallen, Christian

AU - Martinez-Taboada, Victor

AU - Maz, Mehrdad

AU - Merry, Steven

AU - Miller, Jean

AU - Mori, Shunsuke

AU - Neill, Lorna

AU - Nordborg, Elisabeth

AU - Nott, Jennifer

AU - Padbury, Hannah

AU - Pease, Colin

AU - Salvarani, Carlo

AU - Schirmer, Michael

AU - Schmidt, Wolfgang

AU - Spiera, Robert

AU - Tronnier, David

AU - Wagner, Alexandre

AU - Whitlock, Madeline

AU - Matteson, Eric Lawrence

AU - Dasgupta, Bhaskar

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations for PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) recommendations for the management of PMR. We used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology as a framework for the project. Accordingly, the direction and strength of the recommendations are based on the quality of evidence, the balance between desirable and undesirable effects, patients' and clinicians' values and preferences, and resource use. Eight overarching principles and nine specific recommendations were developed covering several aspects of PMR, including basic and follow-up investigations of patients under treatment, risk factor assessment, medical access for patients and specialist referral, treatment strategies such as initial glucocorticoid (GC) doses and subsequent tapering regimens, use of intramuscular GCs and disease modifying anti-rheumatic drugs (DMARDs), as well as the roles of non-steroidal anti-rheumatic drugs and non-pharmacological interventions. These recommendations will inform primary, secondary and tertiary care physicians about an international consensus on the management of PMR. These recommendations should serve to inform clinicians about best practices in the care of patients with PMR.

AB - Therapy for polymyalgia rheumatica (PMR) varies widely in clinical practice as international recommendations for PMR treatment are not currently available. In this paper, we report the 2015 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) recommendations for the management of PMR. We used the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) methodology as a framework for the project. Accordingly, the direction and strength of the recommendations are based on the quality of evidence, the balance between desirable and undesirable effects, patients' and clinicians' values and preferences, and resource use. Eight overarching principles and nine specific recommendations were developed covering several aspects of PMR, including basic and follow-up investigations of patients under treatment, risk factor assessment, medical access for patients and specialist referral, treatment strategies such as initial glucocorticoid (GC) doses and subsequent tapering regimens, use of intramuscular GCs and disease modifying anti-rheumatic drugs (DMARDs), as well as the roles of non-steroidal anti-rheumatic drugs and non-pharmacological interventions. These recommendations will inform primary, secondary and tertiary care physicians about an international consensus on the management of PMR. These recommendations should serve to inform clinicians about best practices in the care of patients with PMR.

UR - http://www.scopus.com/inward/record.url?scp=84941662697&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84941662697&partnerID=8YFLogxK

U2 - 10.1002/art.39333

DO - 10.1002/art.39333

M3 - Article

C2 - 26352874

AN - SCOPUS:84941662697

VL - 67

SP - 2569

EP - 2580

JO - Arthritis and Rheumatology

JF - Arthritis and Rheumatology

SN - 2326-5191

IS - 10

ER -