TY - JOUR
T1 - 2012 Provisional classification criteria for polymyalgia rheumatica
T2 - A European League Against Rheumatism/American College of Rheumatology collaborative initiative
AU - Dasgupta, Bhaskar
AU - Cimmino, Marco A.
AU - Kremers, Hilal Maradit
AU - Schmidt, Wolfgang A.
AU - Schirmer, Michael
AU - Salvarani, Carlo
AU - Bachta, Artur
AU - Dejaco, Christian
AU - Duftner, Christina
AU - Jensen, Hanne Slott
AU - Duhaut, Pierre
AU - Poõr, Gyula
AU - Kaposi, Novák Pál
AU - Mandl, Peter
AU - Balint, Peter V.
AU - Schmidt, Zsuzsa
AU - Iagnocco, Annamaria
AU - Nannini, Carlotta
AU - Cantini, Fabrizio
AU - MacChioni, Pierluigi
AU - Pipitone, Nicolò
AU - Del Amo, Montserrat
AU - Espígol-Frigolé, Georgina
AU - Cid, Maria C.
AU - Martínez-Taboada, Víctor M.
AU - Nordborg, Elisabeth
AU - Direskeneli, Haner
AU - Aydin, Sibel Zehra
AU - Ahmed, Khalid
AU - Hazleman, Brian
AU - Silverman, Barbara
AU - Pease, Colin
AU - Wakefield, Richard J.
AU - Luqmani, Raashid
AU - Abril, Andy
AU - Michet, Clement J.
AU - Marcus, Ralph
AU - Gonter, Neil J.
AU - Maz, Mehrdad
AU - Carter, Rickey E.
AU - Crowson, Cynthia S.
AU - Matteson, Eric L.
PY - 2012/4
Y1 - 2012/4
N2 - The objective of this study was to develop European League Against Rheumatism/American College of Rheumatology classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new-onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring algorithm was developed based on morning stiffness >45 minutes (2 points), hip pain/limited range of motion (1 point), absence of rheumatoid factor and/or anti-citrullinated protein antibody (2 points), and absence of peripheral joint pain (1 point). A score ≥4 had 68% sensitivity and 78% specificity for discriminating all comparison subjects from PMR. The specificity was higher (88%) for discriminating shoulder conditions from PMR and lower (65%) for discriminating RA from PMR. Adding ultrasound, a score ≥5 had increased sensitivity to 66% and specificity to 81%. According to these provisional classification criteria, patients ≥50 years old presenting with bilateral shoulder pain, not better explained by an alternative pathology, can be classified as having PMR in the presence of morning stiffness >45 minutes, elevated C-reactive protein and/or erythrocyte sedimentation rate, and new hip pain. These criteria are not meant for diagnostic purposes.
AB - The objective of this study was to develop European League Against Rheumatism/American College of Rheumatology classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new-onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring algorithm was developed based on morning stiffness >45 minutes (2 points), hip pain/limited range of motion (1 point), absence of rheumatoid factor and/or anti-citrullinated protein antibody (2 points), and absence of peripheral joint pain (1 point). A score ≥4 had 68% sensitivity and 78% specificity for discriminating all comparison subjects from PMR. The specificity was higher (88%) for discriminating shoulder conditions from PMR and lower (65%) for discriminating RA from PMR. Adding ultrasound, a score ≥5 had increased sensitivity to 66% and specificity to 81%. According to these provisional classification criteria, patients ≥50 years old presenting with bilateral shoulder pain, not better explained by an alternative pathology, can be classified as having PMR in the presence of morning stiffness >45 minutes, elevated C-reactive protein and/or erythrocyte sedimentation rate, and new hip pain. These criteria are not meant for diagnostic purposes.
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U2 - 10.1002/art.34356
DO - 10.1002/art.34356
M3 - Article
C2 - 22389040
AN - SCOPUS:84857828277
SN - 0004-3591
VL - 64
SP - 943
EP - 954
JO - Arthritis and rheumatism
JF - Arthritis and rheumatism
IS - 4
ER -