2012 Provisional classification criteria for polymyalgia rheumatica: A European League Against Rheumatism/American College of Rheumatology collaborative initiative

Bhaskar Dasgupta, Marco A. Cimmino, Hilal D Maradit Kremers, Wolfgang A. Schmidt, Michael Schirmer, Carlo Salvarani, Artur Bachta, Christian Dejaco, Christina Duftner, Hanne Slott Jensen, Pierre Duhaut, Gyula Poõr, Novák Pál Kaposi, Peter Mandl, Peter V. Balint, Zsuzsa Schmidt, Annamaria Iagnocco, Carlotta Nannini, Fabrizio Cantini, Pierluigi MacChioniNicolò Pipitone, Montserrat Del Amo, Georgina Espígol-Frigolé, Maria C. Cid, Víctor M. Martínez-Taboada, Elisabeth Nordborg, Haner Direskeneli, Sibel Zehra Aydin, Khalid Ahmed, Brian Hazleman, Barbara Silverman, Colin Pease, Richard J. Wakefield, Raashid Luqmani, Andy Abril, Clement Michet, Ralph Marcus, Neil J. Gonter, Mehrdad Maz, Rickey E. Carter, Cynthia Crowson, Eric Lawrence Matteson

Research output: Contribution to journalArticle

154 Citations (Scopus)

Abstract

The objective of this study was to develop European League Against Rheumatism/American College of Rheumatology classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new-onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring algorithm was developed based on morning stiffness >45 minutes (2 points), hip pain/limited range of motion (1 point), absence of rheumatoid factor and/or anti-citrullinated protein antibody (2 points), and absence of peripheral joint pain (1 point). A score ≥4 had 68% sensitivity and 78% specificity for discriminating all comparison subjects from PMR. The specificity was higher (88%) for discriminating shoulder conditions from PMR and lower (65%) for discriminating RA from PMR. Adding ultrasound, a score ≥5 had increased sensitivity to 66% and specificity to 81%. According to these provisional classification criteria, patients ≥50 years old presenting with bilateral shoulder pain, not better explained by an alternative pathology, can be classified as having PMR in the presence of morning stiffness >45 minutes, elevated C-reactive protein and/or erythrocyte sedimentation rate, and new hip pain. These criteria are not meant for diagnostic purposes.

Original languageEnglish (US)
Pages (from-to)943-954
Number of pages12
JournalArthritis and Rheumatism
Volume64
Issue number4
DOIs
StatePublished - Apr 2012

Fingerprint

Polymyalgia Rheumatica
Hip
Pain
Shoulder Pain
Rheumatoid Factor
Blood Sedimentation
Arthralgia
Articular Range of Motion
C-Reactive Protein
Cohort Studies
Prospective Studies
Pathology
Sensitivity and Specificity
Antibodies

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy
  • Rheumatology
  • Pharmacology (medical)

Cite this

2012 Provisional classification criteria for polymyalgia rheumatica : A European League Against Rheumatism/American College of Rheumatology collaborative initiative. / Dasgupta, Bhaskar; Cimmino, Marco A.; Maradit Kremers, Hilal D; Schmidt, Wolfgang A.; Schirmer, Michael; Salvarani, Carlo; Bachta, Artur; Dejaco, Christian; Duftner, Christina; Jensen, Hanne Slott; Duhaut, Pierre; Poõr, Gyula; Kaposi, Novák Pál; Mandl, Peter; Balint, Peter V.; Schmidt, Zsuzsa; Iagnocco, Annamaria; Nannini, Carlotta; Cantini, Fabrizio; MacChioni, Pierluigi; Pipitone, Nicolò; Del Amo, Montserrat; Espígol-Frigolé, Georgina; Cid, Maria C.; Martínez-Taboada, Víctor M.; Nordborg, Elisabeth; Direskeneli, Haner; Aydin, Sibel Zehra; Ahmed, Khalid; Hazleman, Brian; Silverman, Barbara; Pease, Colin; Wakefield, Richard J.; Luqmani, Raashid; Abril, Andy; Michet, Clement; Marcus, Ralph; Gonter, Neil J.; Maz, Mehrdad; Carter, Rickey E.; Crowson, Cynthia; Matteson, Eric Lawrence.

In: Arthritis and Rheumatism, Vol. 64, No. 4, 04.2012, p. 943-954.

Research output: Contribution to journalArticle

Dasgupta, B, Cimmino, MA, Maradit Kremers, HD, Schmidt, WA, Schirmer, M, Salvarani, C, Bachta, A, Dejaco, C, Duftner, C, Jensen, HS, Duhaut, P, Poõr, G, Kaposi, NP, Mandl, P, Balint, PV, Schmidt, Z, Iagnocco, A, Nannini, C, Cantini, F, MacChioni, P, Pipitone, N, Del Amo, M, Espígol-Frigolé, G, Cid, MC, Martínez-Taboada, VM, Nordborg, E, Direskeneli, H, Aydin, SZ, Ahmed, K, Hazleman, B, Silverman, B, Pease, C, Wakefield, RJ, Luqmani, R, Abril, A, Michet, C, Marcus, R, Gonter, NJ, Maz, M, Carter, RE, Crowson, C & Matteson, EL 2012, '2012 Provisional classification criteria for polymyalgia rheumatica: A European League Against Rheumatism/American College of Rheumatology collaborative initiative', Arthritis and Rheumatism, vol. 64, no. 4, pp. 943-954. https://doi.org/10.1002/art.34356
Dasgupta, Bhaskar ; Cimmino, Marco A. ; Maradit Kremers, Hilal D ; Schmidt, Wolfgang A. ; Schirmer, Michael ; Salvarani, Carlo ; Bachta, Artur ; Dejaco, Christian ; Duftner, Christina ; Jensen, Hanne Slott ; Duhaut, Pierre ; Poõr, Gyula ; Kaposi, Novák Pál ; Mandl, Peter ; Balint, Peter V. ; Schmidt, Zsuzsa ; Iagnocco, Annamaria ; Nannini, Carlotta ; Cantini, Fabrizio ; MacChioni, Pierluigi ; Pipitone, Nicolò ; Del Amo, Montserrat ; Espígol-Frigolé, Georgina ; Cid, Maria C. ; Martínez-Taboada, Víctor M. ; Nordborg, Elisabeth ; Direskeneli, Haner ; Aydin, Sibel Zehra ; Ahmed, Khalid ; Hazleman, Brian ; Silverman, Barbara ; Pease, Colin ; Wakefield, Richard J. ; Luqmani, Raashid ; Abril, Andy ; Michet, Clement ; Marcus, Ralph ; Gonter, Neil J. ; Maz, Mehrdad ; Carter, Rickey E. ; Crowson, Cynthia ; Matteson, Eric Lawrence. / 2012 Provisional classification criteria for polymyalgia rheumatica : A European League Against Rheumatism/American College of Rheumatology collaborative initiative. In: Arthritis and Rheumatism. 2012 ; Vol. 64, No. 4. pp. 943-954.
@article{6052be00dbb042c4bd3e06f1ac65e364,
title = "2012 Provisional classification criteria for polymyalgia rheumatica: A European League Against Rheumatism/American College of Rheumatology collaborative initiative",
abstract = "The objective of this study was to develop European League Against Rheumatism/American College of Rheumatology classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new-onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring algorithm was developed based on morning stiffness >45 minutes (2 points), hip pain/limited range of motion (1 point), absence of rheumatoid factor and/or anti-citrullinated protein antibody (2 points), and absence of peripheral joint pain (1 point). A score ≥4 had 68{\%} sensitivity and 78{\%} specificity for discriminating all comparison subjects from PMR. The specificity was higher (88{\%}) for discriminating shoulder conditions from PMR and lower (65{\%}) for discriminating RA from PMR. Adding ultrasound, a score ≥5 had increased sensitivity to 66{\%} and specificity to 81{\%}. According to these provisional classification criteria, patients ≥50 years old presenting with bilateral shoulder pain, not better explained by an alternative pathology, can be classified as having PMR in the presence of morning stiffness >45 minutes, elevated C-reactive protein and/or erythrocyte sedimentation rate, and new hip pain. These criteria are not meant for diagnostic purposes.",
author = "Bhaskar Dasgupta and Cimmino, {Marco A.} and {Maradit Kremers}, {Hilal D} and Schmidt, {Wolfgang A.} and Michael Schirmer and Carlo Salvarani and Artur Bachta and Christian Dejaco and Christina Duftner and Jensen, {Hanne Slott} and Pierre Duhaut and Gyula Po{\~o}r and Kaposi, {Nov{\'a}k P{\'a}l} and Peter Mandl and Balint, {Peter V.} and Zsuzsa Schmidt and Annamaria Iagnocco and Carlotta Nannini and Fabrizio Cantini and Pierluigi MacChioni and Nicol{\`o} Pipitone and {Del Amo}, Montserrat and Georgina Esp{\'i}gol-Frigol{\'e} and Cid, {Maria C.} and Mart{\'i}nez-Taboada, {V{\'i}ctor M.} and Elisabeth Nordborg and Haner Direskeneli and Aydin, {Sibel Zehra} and Khalid Ahmed and Brian Hazleman and Barbara Silverman and Colin Pease and Wakefield, {Richard J.} and Raashid Luqmani and Andy Abril and Clement Michet and Ralph Marcus and Gonter, {Neil J.} and Mehrdad Maz and Carter, {Rickey E.} and Cynthia Crowson and Matteson, {Eric Lawrence}",
year = "2012",
month = "4",
doi = "10.1002/art.34356",
language = "English (US)",
volume = "64",
pages = "943--954",
journal = "Arthritis and Rheumatology",
issn = "2326-5191",
publisher = "John Wiley and Sons Ltd",
number = "4",

}

TY - JOUR

T1 - 2012 Provisional classification criteria for polymyalgia rheumatica

T2 - A European League Against Rheumatism/American College of Rheumatology collaborative initiative

AU - Dasgupta, Bhaskar

AU - Cimmino, Marco A.

AU - Maradit Kremers, Hilal D

AU - Schmidt, Wolfgang A.

AU - Schirmer, Michael

AU - Salvarani, Carlo

AU - Bachta, Artur

AU - Dejaco, Christian

AU - Duftner, Christina

AU - Jensen, Hanne Slott

AU - Duhaut, Pierre

AU - Poõr, Gyula

AU - Kaposi, Novák Pál

AU - Mandl, Peter

AU - Balint, Peter V.

AU - Schmidt, Zsuzsa

AU - Iagnocco, Annamaria

AU - Nannini, Carlotta

AU - Cantini, Fabrizio

AU - MacChioni, Pierluigi

AU - Pipitone, Nicolò

AU - Del Amo, Montserrat

AU - Espígol-Frigolé, Georgina

AU - Cid, Maria C.

AU - Martínez-Taboada, Víctor M.

AU - Nordborg, Elisabeth

AU - Direskeneli, Haner

AU - Aydin, Sibel Zehra

AU - Ahmed, Khalid

AU - Hazleman, Brian

AU - Silverman, Barbara

AU - Pease, Colin

AU - Wakefield, Richard J.

AU - Luqmani, Raashid

AU - Abril, Andy

AU - Michet, Clement

AU - Marcus, Ralph

AU - Gonter, Neil J.

AU - Maz, Mehrdad

AU - Carter, Rickey E.

AU - Crowson, Cynthia

AU - Matteson, Eric Lawrence

PY - 2012/4

Y1 - 2012/4

N2 - The objective of this study was to develop European League Against Rheumatism/American College of Rheumatology classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new-onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring algorithm was developed based on morning stiffness >45 minutes (2 points), hip pain/limited range of motion (1 point), absence of rheumatoid factor and/or anti-citrullinated protein antibody (2 points), and absence of peripheral joint pain (1 point). A score ≥4 had 68% sensitivity and 78% specificity for discriminating all comparison subjects from PMR. The specificity was higher (88%) for discriminating shoulder conditions from PMR and lower (65%) for discriminating RA from PMR. Adding ultrasound, a score ≥5 had increased sensitivity to 66% and specificity to 81%. According to these provisional classification criteria, patients ≥50 years old presenting with bilateral shoulder pain, not better explained by an alternative pathology, can be classified as having PMR in the presence of morning stiffness >45 minutes, elevated C-reactive protein and/or erythrocyte sedimentation rate, and new hip pain. These criteria are not meant for diagnostic purposes.

AB - The objective of this study was to develop European League Against Rheumatism/American College of Rheumatology classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6-month prospective cohort study of 125 patients with new-onset PMR and 169 non-PMR comparison subjects with conditions mimicking PMR. A scoring algorithm was developed based on morning stiffness >45 minutes (2 points), hip pain/limited range of motion (1 point), absence of rheumatoid factor and/or anti-citrullinated protein antibody (2 points), and absence of peripheral joint pain (1 point). A score ≥4 had 68% sensitivity and 78% specificity for discriminating all comparison subjects from PMR. The specificity was higher (88%) for discriminating shoulder conditions from PMR and lower (65%) for discriminating RA from PMR. Adding ultrasound, a score ≥5 had increased sensitivity to 66% and specificity to 81%. According to these provisional classification criteria, patients ≥50 years old presenting with bilateral shoulder pain, not better explained by an alternative pathology, can be classified as having PMR in the presence of morning stiffness >45 minutes, elevated C-reactive protein and/or erythrocyte sedimentation rate, and new hip pain. These criteria are not meant for diagnostic purposes.

UR - http://www.scopus.com/inward/record.url?scp=84857828277&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84857828277&partnerID=8YFLogxK

U2 - 10.1002/art.34356

DO - 10.1002/art.34356

M3 - Article

C2 - 22389040

AN - SCOPUS:84857828277

VL - 64

SP - 943

EP - 954

JO - Arthritis and Rheumatology

JF - Arthritis and Rheumatology

SN - 2326-5191

IS - 4

ER -