TY - GEN
T1 - 1D Convolutional Neural Networks for Estimation of Compensatory Reserve from Blood Pressure Waveforms
AU - Techentin, Robert W.
AU - Felton, Christopher L.
AU - Schlotman, Taylor E.
AU - Gilbert, Barry K.
AU - Joyner, Michael J.
AU - Curry, Timothy B.
AU - Convertino, Victor A.
AU - Holmes, David R.
AU - Haider, Clifton R.
N1 - Publisher Copyright:
© 2019 IEEE.
PY - 2019/7
Y1 - 2019/7
N2 - We propose a Deep Convolutional Neural Network (CNN) architecture for computing a Compensatory Reserve Metric (CRM) for trauma victims suffering from hypovolemia (decreased circulating blood volume). The CRM is a single health indicator value that ranges from 100% for healthy individuals, down to 0% at hemodynamic decompensation -when the body can no longer compensate for blood loss. The CNN is trained on 20 second blood pressure waveform segments obtained from a finger-cuff monitor of 194 subjects. The model accurately predicts CRM when tested on data from 22 additional human subjects obtained from Lower Body Negative Pressure (LBNP) emulation of hemorrhage, attaining a mean squared error (MSE) of 0.0238 over the full range of values, including those from subjects with both low and high tolerance to central hypovolemia.
AB - We propose a Deep Convolutional Neural Network (CNN) architecture for computing a Compensatory Reserve Metric (CRM) for trauma victims suffering from hypovolemia (decreased circulating blood volume). The CRM is a single health indicator value that ranges from 100% for healthy individuals, down to 0% at hemodynamic decompensation -when the body can no longer compensate for blood loss. The CNN is trained on 20 second blood pressure waveform segments obtained from a finger-cuff monitor of 194 subjects. The model accurately predicts CRM when tested on data from 22 additional human subjects obtained from Lower Body Negative Pressure (LBNP) emulation of hemorrhage, attaining a mean squared error (MSE) of 0.0238 over the full range of values, including those from subjects with both low and high tolerance to central hypovolemia.
UR - http://www.scopus.com/inward/record.url?scp=85077909096&partnerID=8YFLogxK
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U2 - 10.1109/EMBC.2019.8857116
DO - 10.1109/EMBC.2019.8857116
M3 - Conference contribution
C2 - 31946331
AN - SCOPUS:85077909096
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 2169
EP - 2173
BT - 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2019
Y2 - 23 July 2019 through 27 July 2019
ER -