1α,25-Dihydroxyvitamin D3 - Not just a calciotropic hormone

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

1α,25-Dihydroxyvitamin D3, the hormonal form of vitamin D3, is widely appreciated to play a central role in calcium and phosphorous homeostasis. It is becoming increasingly clear, however, that the sterol also plays an important role in the regulation of cellular growth, central nervous system function, and immune responsiveness. In this review, I will highlight some of the mechanisms by which 1α,25-dihydroxyvitamin D3 regulates cellular growth, alters central nervous system function, and immune function.

Original languageEnglish (US)
Pages (from-to)576-581
Number of pages6
JournalNephron
Volume91
Issue number4
DOIs
StatePublished - 2002

Fingerprint

Calcitriol
Central Nervous System
Hormones
Cholecalciferol
Sterols
Growth
Homeostasis
Calcium

Keywords

  • 1α,25(OH)D
  • Growth factors
  • Immune function
  • Vitamin D

ASJC Scopus subject areas

  • Nephrology

Cite this

1α,25-Dihydroxyvitamin D3 - Not just a calciotropic hormone. / Kumar, Rajiv.

In: Nephron, Vol. 91, No. 4, 2002, p. 576-581.

Research output: Contribution to journalArticle

@article{0cfb72f1d1ae4dbe90482a278daade82,
title = "1α,25-Dihydroxyvitamin D3 - Not just a calciotropic hormone",
abstract = "1α,25-Dihydroxyvitamin D3, the hormonal form of vitamin D3, is widely appreciated to play a central role in calcium and phosphorous homeostasis. It is becoming increasingly clear, however, that the sterol also plays an important role in the regulation of cellular growth, central nervous system function, and immune responsiveness. In this review, I will highlight some of the mechanisms by which 1α,25-dihydroxyvitamin D3 regulates cellular growth, alters central nervous system function, and immune function.",
keywords = "1α,25(OH)D, Growth factors, Immune function, Vitamin D",
author = "Rajiv Kumar",
year = "2002",
doi = "10.1159/000065015",
language = "English (US)",
volume = "91",
pages = "576--581",
journal = "Experimental Nephrology",
issn = "1660-8151",
publisher = "S. Karger AG",
number = "4",

}

TY - JOUR

T1 - 1α,25-Dihydroxyvitamin D3 - Not just a calciotropic hormone

AU - Kumar, Rajiv

PY - 2002

Y1 - 2002

N2 - 1α,25-Dihydroxyvitamin D3, the hormonal form of vitamin D3, is widely appreciated to play a central role in calcium and phosphorous homeostasis. It is becoming increasingly clear, however, that the sterol also plays an important role in the regulation of cellular growth, central nervous system function, and immune responsiveness. In this review, I will highlight some of the mechanisms by which 1α,25-dihydroxyvitamin D3 regulates cellular growth, alters central nervous system function, and immune function.

AB - 1α,25-Dihydroxyvitamin D3, the hormonal form of vitamin D3, is widely appreciated to play a central role in calcium and phosphorous homeostasis. It is becoming increasingly clear, however, that the sterol also plays an important role in the regulation of cellular growth, central nervous system function, and immune responsiveness. In this review, I will highlight some of the mechanisms by which 1α,25-dihydroxyvitamin D3 regulates cellular growth, alters central nervous system function, and immune function.

KW - 1α,25(OH)D

KW - Growth factors

KW - Immune function

KW - Vitamin D

UR - http://www.scopus.com/inward/record.url?scp=0035995329&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035995329&partnerID=8YFLogxK

U2 - 10.1159/000065015

DO - 10.1159/000065015

M3 - Article

C2 - 12138257

AN - SCOPUS:0035995329

VL - 91

SP - 576

EP - 581

JO - Experimental Nephrology

JF - Experimental Nephrology

SN - 1660-8151

IS - 4

ER -