Targeting of OGG1 in BER pathway

Project: Research project

Description

Project highlights: the assay was successfully miniaturized and validated using a commercial small molecule library. During this period, the NCGC has fostered and maintained over 180 active collaborations with both NIH and extramural investigators, facilitating drug discovery efforts across the entire spectrum of human disease. These efforts have led to over 100 high-throughput screens and nearly 60 medicinal chemistry campaigns, providing our collaborators and the general research community a wealth of publications and promising small molecule leads. In addition, the NCGC has undertaken a number of informatic challenges to make better use of existing drug and disease target information and provide the general public with easily accessible resources, further catalyzing the development of new therapies for human disease.
StatusFinished
Effective start/end date9/30/066/30/16

Funding

  • National Institutes of Health: $534,809.00
  • National Institutes of Health: $528,375.00
  • National Institutes of Health: $521,942.00
  • National Institutes of Health: $521,942.00

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Informatics
Research
Comparative Effectiveness Research
Costs and Cost Analysis
Medical Informatics
Foster Home Care
Translational Medical Research
Research Personnel
Health
Biostatistics
Feasibility Studies
Ethics
Compliance
Research Design
Computational Biology
Delivery of Health Care
Education
Referral and Consultation
Direction compound

ASJC

  • Medicine(all)