RETINAL GANGLION CELL PROCESSING OF SPATIAL INFORMATION

Project: Research project

Description

This will be quantitative study of how the retinal image in
cats is sampled by three classes of ganglion cells. These
cells (X, Y and Q cells) form the vast majority of cat ganglion
cells with center-surround receptive fields, and, for X and Y
at least, are a major component of the retinogeniculostriate
pathway. An important aspect of the proposed study is that the
spatiotemporal filetering properties will be determined as a
function of retinal position, so that the retinal inhomogeneity
in filtering properties can be quantified. In the same retinas
that these filtering properties of cells are measured, the
sampling arrays of the X and the Y cells from the points where
the recordings were made will be measured anatomically,
allowing comparison between retinal inhomogeneities in sampling
and in filtering properties. With these data, a complete map
of how the retinal image is sampled by these cells will be
obtained. This map should be of considerable use in modeling
the spatiotemporal properties of receptive fields of neurons
located at higher levels of the visual system and ultimately in
modeling spatial vision, binocular vision and stereopsis. It
will also help more immdiately in quantifying descriptions of
local visual field loss due to retinal damage resulting from
diseases of the eye (e.g gaucoma, maculopathies).
StatusActive
Effective start/end date8/1/86 → …

Funding

  • National Institutes of Health
  • National Institutes of Health: $28,600.00
  • National Institutes of Health

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Retinal Pigment Epithelium
Protein Transport
Neural Cell Adhesion Molecules
Retina
Binocular Vision
Depth Perception
Ankyrins
Visual Fields
Ganglia

ASJC

  • Medicine(all)