Molecular regulation of protective CD8 immunity against influenza infection

Project: Research project

Project Details

Description

Narrative The goal of this proposal is to investigate the molecular mechanisms regulating the development of protective CD8 T cell immunity in the respiratory tract during influenza infection. We plan to elucidate the molecular cues, signaling pathways, transcriptional regulation and metabolic control of the development, maintenance and function of anti-influenza tissue-resident memory T cells (TRM). We expect our study will help to design future interventions to promote TRM protective function and long-term maintenance in the lung, which ultimately will aid the design of future influenza therapeutics and/or vaccines.
StatusFinished
Effective start/end date2/10/154/30/22

Funding

  • National Institute of Allergy and Infectious Diseases: $113,996.00

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.