MICROSENSOR FOR INTRAMUSCULAR PRESSURE MEASUREMENT

Project: Research project

Description

Recent advances in microsensor design can be used to refine the
technology of intramuscular pressure measurement. The overall
objective of this project is to design, develop, and test a fiber
optic microsensor which can be used for routine, clinical
measurement of muscle function. Currently, the integrated
electromyogram is used to indicate the timing and intensity of
muscle contraction. However, the problem remains that
electromyographic activity cannot provide a quantitative
measurement of muscle tension under dynamic conditions. An
alternative, measurable parameter related to muscle force is
intramuscular pressure. It is thought that intramuscular pressure
will account for both active and passive muscle tension. However,
currently available intramuscular pressure transducers are too
large for optimum comfort. Microsensor technology is now available
to construct transducers which are approximately the same size as
the fine wires used for electromyographic analysis. The specific
aims of this study are to (1) design and construct a fiber optic
microsensor for measuring intramuscular pressure, and (2) determine
the relationships between intramuscular pressure, muscle sarcomere
length, and muscle tension in an animal model. Successful development of this microsensor will result in a
powerful new tool for quantifying muscle function. This device will
be useful in offering a better representation of muscle tension
under dynamic conditions. It will become an essential tool in
clinical gait analysis aimed at improving mobility of disabled
patients with neuromuscular disorders such as cerebral palsy,
stroke, head injury, spinal cord injury, and poliomyelitis.
StatusFinished
Effective start/end date5/1/946/30/16

Funding

  • National Institutes of Health: $618,266.00
  • National Institutes of Health: $309,642.00
  • National Institutes of Health: $259,522.00
  • National Institutes of Health: $536,612.00
  • National Institutes of Health: $537,543.00
  • National Institutes of Health
  • National Institutes of Health: $509,572.00
  • National Institutes of Health: $593,760.00
  • National Institutes of Health: $595,722.00
  • National Institutes of Health
  • National Institutes of Health: $538,788.00
  • National Institutes of Health
  • National Institutes of Health: $635,904.00
  • National Institutes of Health: $501,743.00

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Pressure
Muscles
Muscle Tonus
Torque
Muscular Diseases
Transducers
Electromyography
Neuromuscular Junction Diseases
Neurophysiological Recruitment
Lambert-Eaton Myasthenic Syndrome
Muscle Contraction
Muscular Dystrophies
Pressure Transducers
Muscle Strength
Polymyositis
Motor Neuron Disease
Tendons
Myasthenia Gravis
Peripheral Nervous System Diseases
Joints

ASJC

  • Medicine(all)