Investigation of common disease mechanisms in nonsyndromic and syndromic PKD

Project: Research project

Project Details

Description

Polycystic kidney diseases (PKD) are a complex group of disorders that cause kidney failure and abnormalities in many other organs due to defects of primary cilia. Here we seek to determine the genetic causes of these diseases, correlate the particular genes and alleles involved with the disease presentation and progression, and develop cellular and whole animal models to fully characterize the diseases. Successful execution will mean a better understanding of the origins of these disease, to more precisely predict the disease courses, determine why the diseases occur, and provide clues for novel therapies.
StatusActive
Effective start/end date4/15/0212/31/22

Funding

  • National Institute of Diabetes and Digestive and Kidney Diseases: $602,289.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $294,864.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $301,960.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $297,332.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $303,400.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $301,960.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $301,960.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $320,248.00

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