The primary aim of this pilot study is to determine the safety and utility of a single intravenous loading dose of AZA to decrease time to response and maintain response in patients with active refractory RA. A secondary aim is to determine the metabolism of AZA in these patients by serial measurement of 6-thioguanine nucleotide.
|Effective start/end date||10/1/97 → 9/30/99|
- National Center for Research Resources
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