Gastrointestinal Cues Influence Metabolic Control of Regulatory T cell Function

Project: Research project

Project Details

Description

PROJECT NARRATIVE The proposal examines how a particular type of immune cell responds to its environment during the development of human inflammatory bowel disease by using animal models and different forms of this immune cell to treat this disease in animals. The goal of our research is to understand how this immune cell, termed “regulatory T cells,” in the intestine can be optimized to better suppress the disease. Information gained from this study will help identify approaches to inhibit excessive inflammation and provide treatment strategies for stopping this debilitating condition that destroys bowel.
StatusActive
Effective start/end date4/1/2012/31/22

Funding

  • National Institute of Diabetes and Digestive and Kidney Diseases: $144,320.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $144,320.00

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