Epithelial stem cell hippo signaling in pulmonary fibrosis

Project: Research project

Project Details

Description

Idiopathic pulmonary fibrosis (IPF) is a relentlessly progressive, and ultimately fatal disorder with a poorly understood pathogenesis and no cure. IPF lungs feature honeycomb regions, which are lined with confused conducting airway epithelial cells stuck in an indeterminate state of differentiation. This grant proposal seeks to determine the role of Hippo signaling in regulating alveolar epithelial regeneration by bronchial and alveolar epithelial stem cells after bleomycin injury.
StatusFinished
Effective start/end date4/23/193/31/22

Funding

  • National Heart, Lung, and Blood Institute: $524,789.00
  • National Heart, Lung, and Blood Institute: $524,789.00

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