CHRONIC ORAL 5-FU IN COMBINATION WITH 776C85

Project: Research project

Project Details

Description

The purpose of this proposal is to evaluate the effect of an AW inhibitor of dihydropyrimidine dexydrogenase (DPD) 776C85 used concomitantly with low oral doses of 5-fluorouracil (5-FU). The study will examine the efficacy of a 28 day dose of the combined drugs on toxicity in a phase I setting in patients with colorectal cancer.
StatusFinished
Effective start/end date10/1/959/30/97

Funding

  • National Center for Research Resources

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