Project: Research project

Project Details


Support is requested to permit participation in the cooperative clinical
trials of Cancer And Leukemia Group B which is dedicated to improving the
treatment of cancer: The University of Alabama at Birmingham will
participate in: Phase II non-randomized studies using historical controls
or randomized studies using concurrent population controls, of the
effectiveness of a specific treatment in a series of patients with
specific cancers; Phase III randomized comparisons of two or more
treatment plans. Emphasis is placed on multi-modality programs and
adjuvant treatment programs. The above studies are directed against
adult cancers, including leukemias, lymphomas, breast cancer, lung
cancer, and other solid tumors. The various modalities being developed
and tested include surgery, radiotherapy, cytotoxic drugs and biologic
response modifiers. Pathology review will be stressed. In addition to
Group studies as described, ancillary studies are encouraged. Thorough
planning, careful review of data, and statistically sound evaluation of
results are essential components. Important secondary benefits of these
studies are the excellence of patient care and improved training of
medical students, house officers and fellows which ensue.
StatusNot started