Calcium Dynamics in Interstitial Cells of Cajal

Project: Research project

Project Details

Description

PROJECT NARRATIVE In order for the gastrointestinal tract to function properly the patterns of contractions in the muscle layers must be tightly regulated and coordinated. An important way to accomplish normal contractile patterns is dependent on a cell type called the interstitial cell of Cajal and on an ion channel, Ano1, which is expressed in interstitial cells of Cajal. This proposal will study how the expression of Ano1 is regulated, how the channel regulates electrical activity of the gastrointestinal tract and how it contributes to both gastrointestinal health and disease.
StatusActive
Effective start/end date4/1/002/28/23

Funding

  • National Institute of Diabetes and Digestive and Kidney Diseases: $345,825.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $323,955.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $268,200.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $321,975.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $254,303.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $261,897.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $215,144.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $345,825.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $202,789.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $394,250.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $249,217.00
  • National Institute of Diabetes and Digestive and Kidney Diseases: $249,217.00

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