A Systems Approach to Targeting Innate Immunity in AD

Project: Research project

Project Details

Description

NARRATIVE Immune dysfunction is a common component of multiple diseases and aging, including Alzheimer’s disease and related disorders (ADRD), Parkinson’s disease and type 2 diabetes (T2D). Under this proposal we plan to dissect the aspects of the immune system implicated across multiple immune-related disorders that are shared and distinct across diseases (Aim 1), tissues (Aim 2) and at the cellular level (Aim 3). These efforts are expected to contribute to the overall goals of the parent U01 award and the AMP-AD consortium to refine known pathways in AD, and uncover new pathways, targets and biomarkers.
StatusActive
Effective start/end date9/20/138/31/22

Funding

  • National Institute on Aging: $1,665,226.00
  • National Institute on Aging: $455,584.00
  • National Institute on Aging: $1,612,430.00
  • National Institute on Aging: $1,597,190.00
  • National Institute on Aging: $1,197,976.00
  • National Institute on Aging: $1,602,041.00
  • National Institute on Aging: $451,500.00
  • National Institute on Aging: $109,143.00
  • National Institute on Aging: $19,179,149.00
  • National Institute on Aging: $391,250.00

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