A BIOTECHNOLOGY RESOURCE CENTER FOR RESEARCH IN LASERS A

  • Wallace, Michael B, (PI)
  • Wallace, Michael B, (PI)
  • Jacgues, S. (PI)
  • Jacques, S. (PI)
  • Gan, L. (PI)
  • Mockel, M. (PI)
  • Cothern, R. (PI)
  • Oseroff, A. (PI)
  • Fitzmaurice, M. (PI)
  • Kramer, J. (PI)
  • Barrios, A.M.Y. (PI)
  • Berger Andrew, J. (PI)
  • Bucshman, R.I.K. (PI)
  • Kowall Neil, W. (PI)
  • Chen, K.U.N. (PI)
  • Christopher, Dub (PI)
  • Bushman, R.I.K. (PI)
  • Christopher, Dub (PI)
  • Barrios, A.M.Y. (PI)
  • Christopher, Dub (PI)
  • Chen, K.U.N. (PI)
  • Bushman, R.I.K. (PI)
  • Renugopalakrishnan, V. (PI)
  • Fu, D.A.X. (PI)
  • Perelman, Lev T. (PI)
  • Perelman, Lev T. (PI)
  • Brennen, James (PI)
  • Zangaro, Renato (PI)
  • Acho, Jacquerine (PI)
  • Orenstein, Jacobo (PI)
  • Rich, Alex (PI)
  • Lathie Devayani, [No Value] (PI)
  • Kollias, Nick (PI)
  • Dhingra, J.A.G. (PI)
  • Oseroff, Allan (PI)
  • Wu, J.U.N. (PI)
  • Jessup, Milburn (PI)
  • Kewen, [No Value] (PI)
  • Selanius, Juhas (PI)
  • Tanaka, Kazunori (PI)
  • Wang, Thomas (PI)
  • Brennan, James (PI)
  • Berger, Andrew (PI)
  • Manoharan, Ramasamy (PI)
  • Dark, Marta (PI)
  • Zonios, George (PI)
  • Itzkan, Irving (PI)
  • Arendt, Joseph (PI)
  • Boustany, Nada (PI)
  • Kneipp, Katrin (PI)
  • Pande, Jayanti (PI)
  • Tannenbaum, Steven (PI)
  • Spencer, Kevin (PI)
  • Lippard, Stephen (PI)
  • Feld, Michael Stephen (PI)
  • Dasari, Ramachandra (PI)
  • Wu, J.U.N. (PI)
  • Lippard, Stephen (PI)
  • Brennen, James (PI)
  • Jacgues, S. (PI)
  • Zangaro, Renato (PI)
  • Jacques, S. (PI)
  • Acho, Jacquerine (PI)
  • Orenstein, Jacobo (PI)
  • Gan, L. (PI)
  • Mockel, M. (PI)
  • Cothern, R. (PI)
  • Rich, Alex (PI)
  • Lathie Devayani, [No Value] (PI)
  • Kollias, Nick (PI)
  • Oseroff, A. (PI)
  • Dhingra, J.A.G. (PI)
  • Jessup, Milburn (PI)
  • Fitzmaurice, M. (PI)
  • Kramer, J. (PI)
  • Kewen, [No Value] (PI)
  • Selanius, Juhas (PI)
  • Tanaka, Kazunori (PI)
  • Wang, Thomas (PI)
  • Brennan, James (PI)
  • Manoharan, Ramasamy (PI)
  • Dark, Marta (PI)
  • Partovi, Farideh (PI)
  • Zonios, George (PI)
  • Arendt, Joseph (PI)
  • Boustany, Nada (PI)
  • Kneipp, Katrin (PI)
  • Barrios, A.M.Y. (PI)
  • Jamieson, Betsy (PI)
  • Hanlon, Eugene (PI)
  • Tannenbaum, Steven (PI)
  • Spencer, Kevin (PI)
  • Feld, Michael Stephen (PI)
  • Dasari, Ramachandra (PI)
  • Salenius, Juha (PI)
  • van, Jacques (PI)
  • Berger Andrew, J. (PI)
  • Bucshman, R.I.K. (PI)
  • Kowall Neil, W. (PI)
  • Yazdi, Youseph (PI)
  • Cothren, Rim- (PI)
  • Dhingra, Jagdish (PI)
  • Deinum, Geurt (PI)
  • Perelman, Lev T. (PI)
  • Yang, Changhuei- (PI)
  • Backman, Vadim (PI)
  • Winn, Joshua - (PI)
  • Chen, K.U.N. (PI)
  • Shafer, Karen (PI)
  • Menezes, Nina (PI)
  • Vaeth, Kathleen (PI)
  • Kwan, Michael (PI)
  • Motz, Jason (PI)
  • Janni, James (PI)
  • Berger, Imre (PI)
  • Tae-Woong, Koo (PI)
  • Shata, Abeer (PI)
  • Nelson, Wilfred (PI)
  • Weinstein, Randy (PI)
  • Pimenta, Marcos (PI)
  • Selenius, Juhas (PI)
  • Tanaka, Toyoichi (PI)
  • Bushman, R.I.K. (PI)
  • Zhang, Qingguo (PI)
  • Valdez, Tulio (PI)
  • Menezes, Nina (PI)
  • Dhingra, Jagdish (PI)
  • Vaeth, Kathleen (PI)
  • Manoharan, Ramasamy (PI)
  • Kwan, Michael (PI)
  • Dark, Marta (PI)
  • Deinum, Geurt (PI)
  • Perelman, Lev T. (PI)
  • Partovi, Farideh (PI)
  • Motz, Jason (PI)
  • Janni, James (PI)
  • Menezes, Nina (PI)
  • Zonios, George (PI)
  • Dhingra, Jagdish (PI)
  • Berger, Imre (PI)
  • Yang, Changhuei- (PI)
  • Arendt, Joseph (PI)
  • Backman, Vadim (PI)
  • Tae-Woong, Koo (PI)
  • Boustany, Nada (PI)
  • Kneipp, Katrin (PI)
  • Barrios, A.M.Y. (PI)
  • Shata, Abeer (PI)
  • Vaeth, Kathleen (PI)
  • Winn, Joshua - (PI)
  • Jamieson, Betsy (PI)
  • Chen, K.U.N. (PI)
  • Nelson, Wilfred (PI)
  • Manoharan, Ramasamy (PI)
  • Weinstein, Randy (PI)
  • Pimenta, Marcos (PI)
  • Selenius, Juhas (PI)
  • Kwan, Michael (PI)
  • Hanlon, Eugene (PI)
  • Tannenbaum, Steven (PI)
  • Tanaka, Toyoichi (PI)
  • Shafer, Karen (PI)
  • Dark, Marta (PI)
  • Deinum, Geurt (PI)
  • Bushman, R.I.K. (PI)
  • Nolan, Edward (PI)
  • Angheloiu, George (PI)
  • Desjardins, Anne (PI)
  • Jang, Hyun Gyung (PI)
  • Lakka, Shoba (PI)
  • Segal, Michael (PI)
  • Vasile, Stefan (PI)
  • Chou, Shin Grace (PI)
  • Russo, Vincent (PI)
  • Scecina, Thomas (PI)
  • Haka, Abigail Susan (PI)
  • Tunnell, James (PI)
  • Gardecki, Joseph (PI)
  • Fang, Christopher (PI)
  • Popescu, Gabriela (PI)
  • Hunter, Martin (PI)
  • Scepanovic, Obrad (PI)
  • Chung-Chieh, Yu (PI)
  • van Oudenaarden, Alexander (PI)
  • Shih, Wei-Heng (PI)
  • Nelson, Wilfred (PI)
  • Kalashnikov, Maxim (PI)
  • Galindo, Luis (PI)
  • Wogan, Gerald (PI)
  • Lau, Corine (PI)
  • Motz, Jason (PI)
  • Nazemi, Jonathan (PI)
  • Bechtel, Kate (PI)
  • McGee, Sasha (PI)
  • Mirkovic, Jelena (PI)
  • Renugopalakrishnan, V. (PI)
  • Kahne, Daniel (PI)
  • Cohen, Anne (PI)
  • Volynskaya, Zoya (PI)
  • Dresselhaus, Mildred (PI)
  • Badizadegan, Kamran (PI)
  • Choi, Woo-Baeg (PI)
  • Singh, Gajendra Pratap (PI)
  • Kalashnikov, Maxim (PI)
  • Lau, Corine (PI)
  • Yaqoob, Zahid (PI)
  • Park, Youngkyu (PI)
  • Barman, Ishan (PI)
  • Sangik, Oh (PI)
  • Kong, Chulho (PI)
  • Kang, Jeon Woong (PI)
  • Yom, Sung (PI)
  • Fu, D.A.X. (PI)
  • Haka, Abigail Susan (PI)
  • Hillman, Tmothy (PI)
  • Choi, Yohan (PI)
  • Weber, Jessie (PI)
  • Dingari, Narahara Chari (PI)
  • Berger, Andrew (PI)
  • Itzkan, Irving (PI)
  • Berger, Andrew (PI)
  • Pande, Jayanti (PI)
  • Gan, L. (PI)
  • Lathie Devayani (PI)
  • Kewen (PI)

Project: Research project

Description

This is a proposal for an NIH Biotechnology Resource Center (BRC) located
in the MIT Spectroscopy Laboratory to support research in the field of
lasers in medicine. It is part of a proposed collaborative program
entitled, "Therapeutic Laser-Tissue Interaction Project". The other
portion, designed as a Program Project, is entitled "Laser Tissue
Interaction Studies" and consists of six interrelated research projects.
The proposed BRC will function in association with the MIT Laser Research
Center (LRC), an NSF supported Regional Instrumentation Facility which
contains one of the largest collections of lasers for basic research in the
US, and will be administered by the MIT Spectroscopy Laboratory. Over the
past four years about 150 projects have been carried out at the LRC in
areas of chemistry, physics, biology and biochemistry, engineering and
applied sciences, and medicine. Of these, about 15% are relevant to
programmatic objectives of the NIH. This grant application proposes to
enlarge the present facilities, staff and activities in five catagories:
(1) core research and development will occur in three areas, (a)
development of a facility containing new tunable infrared laser sources for
use in various types of heating and ablation studies, (b) development of
CARS, LIF and Raman spetral diagnostic techniques for tissue identification
and probes of temperature and constituents, and (c) study of tissue
ablation produced by visible and infrared laser radiation, designed to
establish more effective means for surgical and microsurgical tissue
removal; (2) collaborative research will occur with the six research
projects of the program; (3) projects of outside researchers will be
supported using existing and new facilities and staff; (4) training and
education will be provided through hands-on laboratory experience,
bi-weekly "Seminars in Lasers in Medicine", and annual workshop-minicourse
programs; (5) dissemination of information will occur through our quarterly
publication, "The Spectrograph". Three new laboratories for medical
research will be established. The existing resources of the Center, as
well as the proposed new facilities, will be available to collaborative and
outside researchers. The organizational structure of the LRC already meets
the BRC guidelines and will enlarged to accommodate the increased level of
activity.
StatusFinished
Effective start/end date9/30/855/31/12

Funding

  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health
  • National Institutes of Health

Fingerprint

Spectrum Analysis
Pathology
Biopsy
pathology
Phase transitions
Gels
Spectroscopy
reflectance
Molecular recognition
Molecular interactions
Endoscopes
Infrared absorption
Incisor
Functional groups
spectroscopy
Catalysis
biotechnology
lasers
resources
Tooth

ASJC

  • Medicine(all)