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  Epigenetic Regulation in Primary Sclerosing Cholangitis

  Huebert, R. C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Sclerosing Cholangitis
  • Enhancer of Zeste Homolog 2 Protein
  • Hepatic Stellate Cells
  • Epigenomics
  • Acetylation

• Pediatric Eye Disease Investigator Group Network

  Holmes, J. M.

  Project: Research project

• Peri-electrode large molecule microdialysis of the brain during induced seizures in mice, pigs, and humans with epilepsy undergoing resective surgery

  Howe, C. L. & Worrell, G. A.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Microdialysis
  • Electrodes
  • Epilepsy
  • Swine
  • Seizures

• A Clinical Study of Latiglutenase as a Treatment for Symptom Reduction for Celiac Disease

  Murray, J. A. & Murray, J. A.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • ALV003
  • Celiac Disease
  • Gluten-Free Diet
  • Clinical Studies
  • Therapeutics

• Latiglutenase as a Treatment for Celiac Disease

  Murray, J. A.

  Project: Research project

• The glial mechanism for electrical brain stimulation

  Worrell, G. A. & Wu, L.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Extracellular Vesicles
  • Deep Brain Stimulation
  • Neuroglia
  • Astrocytes
  • Electric Stimulation

• Kruppel-like factor (KLF) 10 regulates intestinal macrophages and experimental colitis

  Papadakis, K.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Kruppel-Like Transcription Factors
  • Factor X
  • Colitis
  • Macrophages
  • Anti-Inflammatory Agents

• EPIDEMIOLOGY OF ALZHEIMER DISEASE IN A TOTAL POPULATION

  Knopman, D. S.

  National Institute on Aging

  Project: Research project

  • Dementia
  • Epidemiology
  • Alzheimer Disease
  • Saints
  • Population

• The neurobiology of two distinct types of progressive apraxia of speech

  Josephs, K. A.

  National Institute on Deafness and Other Communication Disorders

  Project: Research project

  • Apraxias
  • Neurobiology
  • Phonetics
  • Acoustics
  • Neuroimaging

• Molecular Basis of Host-Filovirus Interactions in Pathogenesis

  Ebihara, H. & Kinney, L.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Filoviridae
  • Ebolavirus
  • Nucleoproteins
  • Marburgvirus
  • Ebola Hemorrhagic Fever

• Epigenetic Mechanisms Underlying Hepatitis C-Induced Hepatocarcinogenesis

  Robertson, K. D.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Hepatitis C
  • Hepacivirus
  • Epigenomics
  • Hepatocellular Carcinoma
  • Liver Transplantation

• Mechanisms of age-related susceptibility of NMJ function

  Sieck, G. C. & Mantilla, C. B.

  National Institute on Aging

  Project: Research project

  • Motor Neurons
  • Muscles
  • Brain-Derived Neurotrophic Factor
  • Frailty
  • tropomyosin kinase

• Osteopontin-CD44 role in the malignancy of lateral ventricle infiltrating glioblastoma

  Guerrero Cazares, H.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Osteopontin
  • Lateral Ventricles
  • Glioblastoma
  • Cerebrospinal Fluid
  • Neoplasms

• Tissue Engineered Tendon Complex for Rotator Cuff Repair and Regeneration

  Zhao, C. D.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Project: Research project

  • bones
  • tissues
  • biocompatible materials
  • tissue engineering
  • shoulders

• CANCER AND LEUKEMIA GROUP B

  Diasio, R. B. & Diasio, R. B.

  National Institutes of Health, National Cancer Institute

  Project: Research project

  • Leukemia
  • Historically Controlled Study
  • Neoplasms
  • Lung Neoplasms
  • Population Control

• Targeting cellular senescence with senolytics to improve skeletal health in older humans

  Farr, J. & Khosla, S.

  National Institute on Aging

  Project: Research project

  • Cellular Senescence
  • Health
  • Osteoporosis
  • Chronic Disease
  • Placebos

• PQ6: Role of Cellular Senescence in Late Effects of Childhood Cancer Therapy

  Bram, R. J.

  National Cancer Institute

  Project: Research project

  • cell senescence
  • childhood
  • therapeutics
  • neoplasms
  • toxicity

• Targeted chemotherapy delivery and capture

  Oklu, R.

  National Institute of Biomedical Imaging and Bioengineering

  Project: Research project

  • Drug Therapy
  • Pharmaceutical Preparations
  • Drug-Eluting Stents
  • Drug Liberation
  • Drug-Related Side Effects and Adverse Reactions

• PILOT--A MODEL FOR THE EXPERIMENTAL ANALYSIS OF DERMAL VASCULATURE

  Flotte, T. J.

  National Institutes of Health

  Project: Research project

  • Melanoma
  • Lasers
  • Incidence
  • Proteomics
  • Immunotherapy

• Senescent Vascular Cells as Mediators of Cognitive Decline

  Marissa, S.

  National Institute on Aging

  Project: Research project

  • Cognitive Dysfunction
  • Cellular Senescence
  • Blood Vessels
  • Cognition
  • Ink

• Role of the Syx-RhoA signaling axis in glioma cell growth and dissemination

  Anastasiadis, P. Z.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Glioma
  • Cell Movement
  • Growth
  • Standard of Care
  • Cell Division

• Impact of Clot Histological and Physical Properties on Revascularization Strategies in Acute Ischaemic Stroke

  Brinjikji, W.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Stroke
  • Thrombectomy
  • Embolism
  • Phenotype
  • In Vitro Techniques

• Detection of somatic, subclonal and mosaic CNVs from sequencing

  Abyzov, A.

  National Cancer Institute

  Project: Research project

  • Whole Genome Sequencing
  • Medicine
  • Genome
  • Neoplasms
  • Human Genetics

• RESEARCH TRIANGLE INSTITUTE/PROGRAMMING AND ANALYTICAL SUPPORT

  Limburg, P. J., Erlichman, C. & Limburg, P. J.

  National Cancer Institute

  Project: Research project

  • Erlotinib Hydrochloride
  • DNA Vaccines
  • Clinical Trials
  • Contracts
  • Chronic Hepatitis C

• Distinct Pathways of VPF/VEGF Receptors

  Mukhopadhyay, D.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Neuropilin-1
  • Vascular Endothelial Growth Factor Receptor
  • Cardiomyopathies
  • Vascular Endothelial Growth Factor A
  • Vascular Endothelial Growth Factor B

• Multi-purpose use of a patient-reported measure of treatment burden in primary care

  Eton, D. T.

  National Institute of Nursing Research

  Project: Research project

  • Primary Health Care
  • Multiple Chronic Conditions
  • Self Care
  • Self-Management
  • Therapeutics

• Autoimmune Mechanisms in Human Myocarditis

  Cooper, L. T. J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Myocarditis
  • Cardiac Myosins
  • Dilated Cardiomyopathy
  • Monocytes
  • Heart Failure

• Injectable and Moldable Composite Bone Scaffolds for Spinal Fusion

  Yaszemski, M. J.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Project: Research project

  • bones
  • fusion
  • composite materials
  • propylene
  • animal models

• Home Based Rehabilitation for COPD

  Benzo, R. P.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Chronic Obstructive Pulmonary Disease
  • Rehabilitation
  • Lung
  • Self-Management
  • Professional Practice Gaps

• Molecular Dissection of Aggressive B-Cell Lymphomas

  Rimsza, L.

  National Cancer Institute

  Project: Research project

  • Lymphoma
  • grant
  • B-Cell Lymphoma
  • Genomics
  • Biostatistics

• Cellular Responses to Localized Oxidative Stress

  Flotte, T. J.

  National Cancer Institute

  Project: Research project

  • Microscopic examination
  • Flow cytometry
  • Laser beam effects
  • Personnel
  • Confocal microscopy

• NUTRIENT HOMEOSTASIS--COORDINATION OF RESPONSE BY THE NUCLEUS TRACTIS SOLITARIUS

  Smith, D. I., Kinney, L. & Kinney, L.

  National Institute of General Medical Sciences

  Project: Research project

  • Human Chromosomes
  • Tumor Suppressor Genes
  • Familial renal cell carcinoma
  • Organism Cloning
  • Renal Cell Carcinoma

• Cerebral Microbleeds in the Aging Population

  Graff-Radford, J.

  National Institute on Aging

  Project: Research project

  • Positron-Emission Tomography
  • Neuroimaging
  • Organized Financing
  • Cerebral Hemorrhage
  • Amyloid

• Lipotoxicity and Liver Inflammation

  Ibrahim, S. H.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Extracellular Vesicles
  • Hepatocytes
  • Inflammation
  • Liver
  • Integrins

• Hypertensive pregnancy disorders and future coronary artery disease

  Garovic, V. D.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Coronary Artery Disease
  • Pregnancy
  • Pre-Eclampsia
  • Reproductive History
  • Epidemiology

• Integration of Genomic and Clinical Data to Enhance Subtyping of Colon Cancer

  Sinicrope, F. A.

  National Cancer Institute

  Project: Research project

  • Colonic Neoplasms
  • Consensus
  • Gene Expression
  • Survival
  • Learning

• Role of senescent cells in the pathogenesis of Marfan-associated cardiovascular disease

  Miller, J. D.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Marfan Syndrome
  • Cardiovascular Diseases
  • Mitral Valve
  • Aortic Valve
  • Phenotype

• GENETIC REGULATION OF MITOCHONDRIAL MEMBRANE BIOGENESIS

  Smith, D. I., Kinney, L. & Kinney, L.

  National Institute of General Medical Sciences

  Project: Research project

• ST8Sia6 expression on tumors inhibits the immune response

  Shapiro, V. M.

  National Cancer Institute

  Project: Research project

  • Sialic Acid Binding Immunoglobulin-like Lectins
  • Neoplasms
  • N-Acetylneuraminic Acid
  • Growth
  • Transferases

• Social Media Intervention to Promote Smoking Treatment Utilization and Cessation among Alaska Native Smokers

  Patten, C. A.

  National Institute on Drug Abuse

  Project: Research project

  • Alaska Natives
  • Social Media
  • Withholding Treatment
  • Smokers
  • Smoking

• NATIVE NETWORK CANCER RESOURCES CENTER

  Kaur, J. S. & Kinney, L.

  National Cancer Institute

  Project: Research project

  • Cancer
  • Alaska Natives
  • American Indians
  • neoplasms
  • Resources

• Technology-enhanced Transitional Palliative Care for Family Caregivers in Rural Settings

  Griffin, J.

  National Institute of Nursing Research

  Project: Research project

  • Transitional Care
  • Palliative Care
  • Caregivers
  • Technology
  • Medically Underserved Area

• Hemorrhage control in the irreversible anticoagulated patient

  Oklu, R.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Hemorrhage
  • Biocompatible Materials
  • Thrombosis
  • Mortality
  • Emergencies

• Generation of a Brain-specific PAPP-A Knock-out Mice

  Conover, C. A.

  National Institute on Aging

  Project: Research project

  • Pregnancy-Associated Plasma Protein-A
  • Knockout Mice
  • Somatomedins
  • Brain
  • Longevity

• 4D CT Imaging for Improved Diagnosis and Treatment of Wrist Ligament Injuries

  Zhao, K. D.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Project: Research project

  • Wrist Injuries
  • Four-Dimensional Computed Tomography
  • Ligaments
  • Wounds and Injuries
  • Osteoarthritis

• Advanced preoperative assessment of meningiomas

  Murphy, M.

  National Institute of Biomedical Imaging and Bioengineering

  Project: Research project

  • Tumors
  • Stiffness
  • Magnetic resonance
  • Imaging techniques
  • Classifiers

• Role of CD38 in NAD metabolism: from the basic biology of aging to translation

  Chini, E. N.

  National Institute on Aging

  Project: Research project

  • NAD
  • NAD+ Nucleosidase
  • Longevity
  • nicotinamide-beta-riboside
  • Nicotinamide Mononucleotide

• Structural biology of DNA damage response in chromatin

  Mer, G.

  National Institute of General Medical Sciences

  Project: Research project

  • Chromatin
  • DNA Damage
  • Post Translational Protein Processing
  • Nucleosomes
  • Homologous Recombination

• Adipose-derived biogenic nanoparticles for treatment of myocarditis/DCM(MPDPI)

  Wolfram, J. & Fairweather, D.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Myocarditis
  • Dilated Cardiomyopathy
  • Nanoparticles
  • Toll-Like Receptor 4
  • Anti-Inflammatory Agents

• COMPUTER SCIENCE UNIT

  Adjei, A.

  National Cancer Institute

  Project: Research project

  • neoplasms
  • research support
  • protocols
  • Advisory Committees
  • monitoring