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  Mechanisms of Processivity in Molecular Motors

  Rosenfeld, S. & Kinney, L.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Project: Research project

  • kinesin
  • enzymology
  • myosin
  • physiology
  • transporters

• ROLE OF MYOSINS I AND II IN CELL MOTILITY

  Rosenfeld, S.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Myosin Type I
  • Myosin Type II
  • Myosins
  • Cell Movement
  • Actins

• Molecular Mechanisms of Cholestatic Fibrogenesis

  Huebert, R. C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Enhancer of Zeste Homolog 2 Protein
  • Hepatic Stellate Cells
  • Fibronectins
  • Acetylation
  • Fibrosis

• (PQD1) Clonal heterogeneity and targeted therapy resistance in melanoma

  Sekulic, A. D. & Kinney, L.

  National Cancer Institute

  Project: Research project

  • Melanoma
  • Neoplasms
  • Therapeutics
  • Informatics
  • Dreams

• Clinical evaluation of combination oncolytic viro-immunotherapy for solid tumors

  Adjei, A. & Adjei, A.

  National Cancer Institute

  Project: Research project

  • Immunotherapy
  • Vesicular Stomatitis
  • Oncolytic Virotherapy
  • Non-Small Cell Lung Carcinoma
  • Neoplasms

• Engineering an HIV-resistant immune system for HIV cure

  Fadel, H.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • HIV-1
  • Immune System
  • HIV
  • Hematopoietic Stem Cells
  • Genetic Therapy

• 3q26 Amplified Genes as Cooperative Oncogenic Drivers of Lung Squamous Cell Carcinoma

  Justilien, V.

  National Cancer Institute

  Project: Research project

  • Squamous Cell Carcinoma
  • Lung
  • Genes
  • Stem Cells
  • Epithelial Cells

• Microsystems for Modeling Neurodevelopmental Disorders

  Revzin, A.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Neurodevelopmental Disorders
  • Down Syndrome
  • Astrocytes
  • Induced Pluripotent Stem Cells
  • Synapses

• Mechanisms of alteration of gastrointestinal physiology by gut microbes

  Kashyap, P. C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • tryptamine
  • digestive system
  • physiology
  • microorganisms
  • irritable bowel syndrome

• Peripheral Mechanisms of Cardiopulmonary Control during Exercise

  Olson, T. P.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Heart Failure
  • Exercise
  • Muscles
  • Hemodynamics
  • Ventilation

• Development of Mantle Cell Lymphoma Proliferation Signature Assay

  Rimsza, L.

  National Cancer Institute

  Project: Research project

  • Mantle-Cell Lymphoma
  • Cell Proliferation
  • Gene Expression Profiling
  • Clinical Trials
  • Ki-67 Antigen

• Mechanisms of mechanotransduction in the enterochromaffin cells

  Beyder, A.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Enterochromaffin Cells
  • Serotonin
  • Ion Channels
  • Gastrointestinal Motility
  • Organoids

• Manipulating tau's posttranslational modifications to block disease progression in vivo

  Cook, C.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Tauopathies
  • Post Translational Protein Processing
  • Disease Progression
  • Acetylation
  • Histone Deacetylase 6

• Mechanisms of IL-33 secretion in allergic diseases

  Kita, H.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Interleukin-33
  • Allergens
  • Adenosine Triphosphate
  • Epithelium
  • Oxidative Stress

• Role of the Syx-RhoA signaling axis in glioma cell growth and dissemination

  Anastasiadis, P. Z.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Glioma
  • Cell Movement
  • Growth
  • Standard of Care
  • Cell Division

• Genetic Markers of Long-Term Mumps Vaccine Immunity

  Kennedy, R. B.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Mumps Vaccine
  • Genetic Markers
  • Immunity
  • Mumps
  • Single Nucleotide Polymorphism

• Extracellular vesicle RNA signaling in liver tumor microenvironment

  Patel, T. C.

  National Cancer Institute

  Project: Research project

  • Extracellular Vesicles
  • Tumor Microenvironment
  • RNA
  • Liver
  • Liver Neoplasms

• Systems Biology of Mumps Vaccine Response

  Kennedy, R. B.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Mumps Vaccine
  • Mumps
  • Systems Biology
  • Immunity
  • B-Lymphocytes

• Pre-Clinical Novel Radiosensitizer Evaluation Program for Brain Tumors

  Sarkaria, J. N.

  National Cancer Institute

  Project: Research project

  • Program Evaluation
  • Glioblastoma
  • Brain Neoplasms
  • Radio
  • Radiation-Sensitizing Agents

• Center for Modeling Tumor Cell Migration Mechanics: Administrative Core

  Rosenfeld, S.

  National Cancer Institute

  Project: Research project

  • Mechanics
  • Cell Movement
  • Neoplasms
  • Tumor Microenvironment
  • Reverse Genetics

• Modeling and microsystems approach to glioma invasion

  Rosenfeld, S., Kinney, L., Kinney, L. & Rosenfeld, S.

  National Cancer Institute

  Project: Research project

  • Glioma
  • Brain
  • Hydrogels
  • Glioblastoma
  • Adhesiveness

• Nuclear Pore Complex and as a Contributor to Tau Associated Dementia

  Petrucelli, L.

  National Institute on Aging

  Project: Research project

  • Nuclear Pore
  • Dementia
  • Cell Nucleus Active Transport
  • Alzheimer Disease
  • Tauopathies

• Translational Geroscience Network

  Kirkland, J. L.

  National Institute on Aging

  Project: Research project

  • Proteostasis
  • Clinical Trials
  • Idiopathic Pulmonary Fibrosis
  • Frailty
  • Organized Financing

• Functions of the PH-Domain Leucine Rich Protein Phosphatase (Phlpp)1 in Osteoclasts

  Bradley, E.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Project: Research project

  • Pleckstrin Homology Domains
  • Protein Phosphatase 1
  • Osteoclasts
  • Leucine
  • Osteogenesis

• Epigenetic Regulation in Primary Sclerosing Cholangitis

  Huebert, R. C.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Sclerosing Cholangitis
  • Enhancer of Zeste Homolog 2 Protein
  • Hepatic Stellate Cells
  • Epigenomics
  • Acetylation

• IMMUNOGENICITY OF A XENOGENEIC BIOARTIFICAL LIVER

  Nyberg, S. & Kinney, L.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Artificial Liver
  • Liver
  • Acute Liver Failure
  • Hepatocytes
  • Liver Failure

• Credentialing a Genetically Engineered Clinically-Relevant Mouse Model of Multiple Myeloma

  Chesi, M.

  National Cancer Institute

  Project: Research project

  • Credentialing
  • Multiple Myeloma
  • Transgenic Mice
  • pomalidomide
  • Lenalidomide

• Spinal Muscular Atrophy: Cell-based drug screens for treatment of axonal defects

  Rossoll, W. & Kinney, L.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Spinal Muscular Atrophy
  • Motor Neurons
  • Pharmaceutical Preparations
  • Growth Cones
  • Actins

• CLINICAL STUDIES OF SIGNAL TRANSDUCTION INHIBITORS

  Adjei, A.

  National Cancer Institute

  Project: Research project

  • Sirolimus
  • Signal Transduction
  • Clinical Studies
  • TOR Serine-Threonine Kinases
  • Neoplasms

• Regulating pulmonary inflammation by type I IFN signaling in neutrophils during i

  Sun, J. & Kinney, L.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Eragrostis
  • Interleukin-10
  • Interleukin-27
  • Pneumonia
  • Neutrophils

• Corticosteroid Insensitivity in the Neonatal and Pediatric Airway Diseases

  Britt, R. J. & Kinney, L.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Adrenal Cortex Hormones
  • Pediatrics
  • Vitamin D
  • Asthma
  • Inflammation

• The contribution of p16-expressing cells to tauopathy

  Baker, D. J.

  National Institute on Aging

  Project: Research project

  • Tauopathies
  • Cellular Senescence
  • Alzheimer Disease
  • Pathology
  • Synthetic Drugs

• Molecular imaging and system dynamics of tumor virotherapy

  Dingli, D. M., Kinney, L. & Kinney, L.

  National Cancer Institute

  Project: Research project

  • Molecular Imaging
  • Viruses
  • Neoplasms
  • Measles virus
  • Vesicular Stomatitis

• Mayo Clinic Physical Activity Research Center: Metabolomics and Proteomics Analysis Site

  Lanza, I. R.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Metabolomics
  • Proteomics
  • Metabolites
  • Plasmas
  • Muscle

• Glutamatergic and GABAergic Biomarkers in rTMS for Adolescent Depression

  Croarkin, P. E.

  National Institute of Mental Health

  Project: Research project

  • Transcranial Magnetic Stimulation
  • Biomarkers
  • Depression
  • gamma-Aminobutyric Acid
  • Glutamic Acid

• Effects of Microengineered Interactions on Liver-Specific Gene Expression

  Revzin, A. & Kinney, L.

  National Institute of Diabetes and Digestive and Kidney Diseases

  Project: Research project

  • Gene Expression
  • Liver
  • Hepatocytes
  • Cell Culture Techniques
  • Human Embryonic Stem Cells

• Novel Peptide Therapeutics for Hypertension

  Burnett, J. C. J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Atrial Natriuretic Factor
  • Hypertension
  • Peptides
  • Blood Pressure
  • Aldosterone

• THERAPEUTIC STUDIES OF ANAPLASTIC GLIOMAS

  Rosenfeld, S. & Kinney, L.

  National Cancer Institute

  Project: Research project

  • Brain Neoplasms
  • Glioma
  • Biostatistics
  • Therapeutics
  • Phase II Clinical Trials

• The Role of Cellular Senescence in Mediating Age-Related Bone Loss

  Farr, J.

  National Institute of Arthritis and Musculoskeletal and Skin Diseases

  Project: Research project

  • Cellular Senescence
  • Osteoporosis
  • Osteocytes
  • Synthetic Drugs
  • Pathology

• Generation of a Brain-specific PAPP-A Knock-out Mice

  Conover, C. A.

  National Institute on Aging

  Project: Research project

  • Pregnancy-Associated Plasma Protein-A
  • Knockout Mice
  • Somatomedins
  • Brain
  • Longevity

• Molecular Basis of Host-Filovirus Interactions in Pathogenesis

  Ebihara, H. & Kinney, L.

  National Institute of Allergy and Infectious Diseases

  Project: Research project

  • Filoviridae
  • Ebolavirus
  • Nucleoproteins
  • Marburgvirus
  • Ebola Hemorrhagic Fever

• Predictors of change in prosocial attitudes during medical education

  Phelan, S. M.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • school climate
  • shortage
  • Healthcare Providers
  • education
  • medicine

• Reproductive risk factors for Alzheimer's disease dementia and pathology

  Mielke, M. M.

  National Institute on Aging

  Project: Research project

  • Alzheimer Disease
  • Pathology
  • Pregnancy
  • Menopause
  • Cognitive Dysfunction

• Harnessing the Electronic Health Record to Predict Risk of Cardiovascular Disease

  Bielinski, S. J.

  National Heart, Lung, and Blood Institute

  Project: Research project

  • Electronic Health Records
  • Cardiovascular Diseases
  • Deep Learning
  • Natural Language Processing
  • Reproductive History

• The role of X chromosome inactivation in ovarian cancer

  Winham, S. J.

  National Cancer Institute

  Project: Research project

  • X Chromosome Inactivation
  • Ovarian Neoplasms
  • Neoplasms
  • X-Linked Genes
  • Chromosomes

• Oncolytic Virotherapy in Hepatocellular Cancer

  Borad, M. J.

  National Cancer Institute

  Project: Research project

  • Oncolytic Virotherapy
  • Liver Neoplasms
  • Vesicular Stomatitis
  • Measles virus
  • Interferon-beta

• ICAM-1 GENE EXPRESSION IN MALIGNANT GLIAL TUMORS

  Rosenfeld, S. & Rosenfeld, S.

  National Institutes of Health, National Institute of Neurological Disorders and Stroke

  Project: Research project

  • glioma
  • neuroglia
  • cell biology
  • molecular biology
  • Glioma

• Molecular Discriminators in Benign Breast Tissue for Future Risk of ER positive a

  Degnim, A. C.

  National Cancer Institute

  Project: Research project

  • Breast
  • Breast Neoplasms
  • Mutation
  • Biopsy
  • Neoplasms

• Longitudinal Imaging Biomarkers of Disease Progression in DLB

  Boeve, B. F.

  National Institute of Neurological Disorders and Stroke

  Project: Research project

  • Lewy Body Disease
  • Disease Progression
  • Biomarkers
  • Alzheimer Disease
  • Pathologic Processes

• Studying microglial function using cell ablation approaches

  Wu, L.

  National Institute of Dental and Craniofacial Research

  Project: Research project

  • Neuralgia
  • Microglia
  • Peripheral Nerve Injuries
  • Maintenance
  • Macrophages