5-FU AND RADIOLABLED ZIDOVUDINE (3H-AZT) IN COLORECTAL CANCER

Project: Research project

Project Details

Description

Treatment of choice for advanced disease is 5-FU, however response rate to this therapy is low. Recent reports detail increased cytotoxicity against a human colorectal carcinoma cell line with combined 5-FU & AZT. This trial of AZT & 5-FU will assess concomitant administration of these agents, & fully detail the metabolic & pharmacokinetic profile of AZT before evaluating combined AZT & 5-FU.
StatusFinished
Effective start/end date10/1/919/30/95

Funding

  • National Center for Research Resources

Fingerprint

Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.