Zhaoyu Li, PhD

  • 1509 Citations
  • 15 Scopus h-Index
20002019
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Research Output 2000 2019

  • 1509 Citations
  • 15 Scopus h-Index
  • 26 Article
  • 1 Short survey
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Article
2019
Open Access
Histone Code
Nucleosomes
Epigenomics
Biological Phenomena
Base Pairing

Sexual dimorphism in the incidence of human cancers

Zheng, D., Trynda, J., Williams, C., Vold, J. A., Nguyen, J. H., Harnois, D., Bagaria, S. P., McLaughlin, S. A. & Li, Z., Jul 12 2019, In : BMC cancer. 19, 1, 684.

Research output: Contribution to journalArticle

Open Access
Sex Characteristics
Incidence
Neoplasms
Precision Medicine
Sweden
2018
3 Citations (Scopus)

A droplet microfluidic platform for efficient enzymatic chromatin digestion enables robust determination of nucleosome positioning

Xu, Y., Lee, J. H., Li, Z., Wang, L., Ordog, T. & Bailey, R. C., Jan 1 2018, In : Lab on a Chip. 18, 17, p. 2583-2592 10 p.

Research output: Contribution to journalArticle

Microfluidics
Nucleosomes
Chromatin
Digestion
DNA
2016
16 Citations (Scopus)

FOXA1 defines cancer cell specificity

Zhang, G., Zhao, Y., Liu, Y., Kao, L. P., Wang, X., Skerry, B. & Li, Z., Mar 1 2016, In : Science advances. 2, 3, p. e1501473

Research output: Contribution to journalArticle

Neoplasms
Transcription Factors
Hepatocyte Nuclear Factor 3-alpha
Clustered Regularly Interspaced Short Palindromic Repeats
Organogenesis
4 Citations (Scopus)

Foxa1 is essential for mammary duct formation

Liu, Y., Zhao, Y., Skerry, B., Wang, X., Colin-Cassin, C., Radisky, D. C., Kaestner, K. H. & Li, Z., 2016, (Accepted/In press) In : Genesis.

Research output: Contribution to journalArticle

Breast
Breast Neoplasms
Hepatocyte Nuclear Factor 3-alpha
Epithelial Cells
Estrogen Receptor alpha
6 Citations (Scopus)

Genomics of sex hormone receptor signaling in hepatic sexual dimorphism

Zheng, D., Wang, X., Antonson, P., Gustafsson, J. Å. & Li, Z., Dec 16 2016, (Accepted/In press) In : Molecular and Cellular Endocrinology.

Research output: Contribution to journalArticle

Gonadal Steroid Hormones
Genomics
Sex Characteristics
Liver
Estrogen Receptor alpha
2015
25 Citations (Scopus)

Interplay of estrogen receptors and FOXA factors in the liver cancer

Zhao, Y. & Li, Z., Dec 15 2015, In : Molecular and Cellular Endocrinology. 418, p. 334-339 6 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Estrogen Receptors
Liver
Sex Characteristics
Rodentia
6 Citations (Scopus)

Protein tyrosine phosphatase of liver regeneration-1 is required for normal timing of cell cycle progression during liver regeneration

Jiao, Y., Ye, D. Z., Li, Z., Teta-Bissett, M., Peng, Y., Taub, R., Greenbaum, L. E. & Kaestner, K. H., Jan 15 2015, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 308, 2, p. G85-G91

Research output: Contribution to journalArticle

Liver Regeneration
Protein Tyrosine Phosphatases
Cell Cycle
Liver
Hepatectomy
2013
145 Citations (Scopus)

DANPOS: Dynamic analysis of nucleosome position and occupancy by sequencing

Chen, K., Xi, Y., Pan, X., Li, Z., Kaestner, K., Tyler, J., Dent, S., He, X. & Li, W., Feb 2013, In : Genome Research. 23, 2, p. 341-351 11 p.

Research output: Contribution to journalArticle

Nucleosomes
Nucleotides
Genome
Nucleic Acid Regulatory Sequences
Hematopoietic Stem Cells
2012
185 Citations (Scopus)

Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer

Li, Z., Tuteja, G., Schug, J. & Kaestner, K. H., Jan 20 2012, In : Cell. 148, 1-2, p. 72-83 12 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Sex Characteristics
Estrogen Receptors
Liver
Androgens
125 Citations (Scopus)

Foxa2 and H2A.Z mediate nucleosome depletion during embryonic stem cell differentiation

Li, Z., Gadue, P., Chen, K., Jiao, Y., Tuteja, G., Schug, J., Li, W. & Kaestner, K. H., Dec 21 2012, In : Cell. 151, 7, p. 1608-1616 9 p.

Research output: Contribution to journalArticle

Nucleosomes
Embryonic Stem Cells
Stem cells
Cell Differentiation
Occupations
38 Citations (Scopus)

Overexpression of hepatocyte nuclear factor-4α initiates cell cycle entry, but is not sufficient to promote β-cell expansion in human islets

Rieck, S., Zhang, J., Li, Z., Liu, C., Naji, A., Takane, K. K., Fiaschi-Taesch, N. M., Stewart, A. F., Kushner, J. A. & Kaestner, K. H., Sep 2012, In : Molecular Endocrinology. 26, 9, p. 1590-1602 13 p.

Research output: Contribution to journalArticle

Hepatocyte Nuclear Factor 4
Cell Cycle
Cyclin D3
DNA Damage
Cell Proliferation
2011
49 Citations (Scopus)

Species-specific strategies underlying conserved functions of metabolic transcription factors

Soccio, R. E., Tuteja, G., Everett, L. J., Li, Z., Lazar, M. A. & Kaestner, K. H., Apr 2011, In : Molecular Endocrinology. 25, 4, p. 694-706 13 p.

Research output: Contribution to journalArticle

Transcription Factors
Peroxisome Proliferator-Activated Receptors
Genes
Binding Sites
Adipocytes
57 Citations (Scopus)

The nucleosome map of the mammalian liver

Li, Z., Schug, J., Tuteja, G., White, P. & Kaestner, K. H., Jun 2011, In : Nature Structural and Molecular Biology. 18, 6, p. 742-746 5 p.

Research output: Contribution to journalArticle

Nucleosomes
Liver
Chromatin
Winged-Helix Transcription Factors
Binding Sites
5 Citations (Scopus)

The role of phosphatidylethanolamine methyltransferase in a mouse model of intrahepatic cholestasis

Li, Z., Agellon, L. B. & Vance, D. E., Apr 2011, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1811, 4, p. 278-283 6 p.

Research output: Contribution to journalArticle

Phosphatidylethanolamine N-Methyltransferase
Intrahepatic Cholestasis
Bile Acids and Salts
Liver
Intestinal Absorption
2009
86 Citations (Scopus)

Foxa1 and Foxa2 regulate bile duct development in mice

Li, Z., White, P., Tuteja, G., Rubins, N., Sackett, S. & Kaestner, K. H., Jun 1 2009, In : Journal of Clinical Investigation. 119, 6, p. 1537-1545 9 p.

Research output: Contribution to journalArticle

Bile Ducts
Interleukin-6
Liver
Glucocorticoid Receptors
Hepatocyte Nuclear Factor 3-alpha
2008
288 Citations (Scopus)

Phosphatidylcholine and choline homeostasis

Li, Z. & Vance, D. E., Jun 1 2008, In : Journal of Lipid Research. 49, 6, p. 1187-1194 8 p.

Research output: Contribution to journalArticle

Choline
Phosphatidylcholines
Homeostasis
Liver
Choline Kinase
2007
9 Citations (Scopus)

A role for high density lipoproteins in hepatic phosphatidylcholine homeostasis

Li, Z., Agellon, L. B. & Vance, D. E., Jul 2007, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1771, 7, p. 893-900 8 p.

Research output: Contribution to journalArticle

HDL Lipoproteins
Choline
Phosphatidylcholines
Homeostasis
Liver
5 Citations (Scopus)

Choline cannot be replaced by propanolamine in mice

Li, Z. & Vance, D. E., Apr 2007, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1771, 4, p. 486-490 5 p.

Research output: Contribution to journalArticle

Propanolamines
Choline
2-Propanol
Diet
Phosphatidylethanolamine N-Methyltransferase
27 Citations (Scopus)

Choline redistribution during adaptation to choline deprivation

Li, Z., Agellon, L. B. & Vance, D. E., Apr 6 2007, In : Journal of Biological Chemistry. 282, 14, p. 10283-10289 7 p.

Research output: Contribution to journalArticle

Choline
Phosphatidylethanolamine N-Methyltransferase
Liver
choline oxidase
Recycling
48 Citations (Scopus)

Hepatic phosphatidylethanolamine N-methyltransferase, unexpected roles in animal biochemistry and physiology

Vance, D. E., Li, Z. & Jacobs, R. L., Nov 16 2007, In : Journal of Biological Chemistry. 282, 46, p. 33237-33241 5 p.

Research output: Contribution to journalArticle

Phosphatidylethanolamine N-Methyltransferase
Biochemistry
Fluorescence microscopy
Physiology
Choline
2006
273 Citations (Scopus)

The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis

Li, Z., Agellon, L. B., Allen, T. M., Umeda, M., Jewell, L., Mason, A. & Vance, D. E., May 2006, In : Cell Metabolism. 3, 5, p. 321-331 11 p.

Research output: Contribution to journalArticle

Fatty Liver
Phosphatidylcholines
Choline
Membranes
Liver Failure
2005
92 Citations (Scopus)

Phosphatidylcholine homeostasis and liver failure

Li, Z., Agellon, L. B. & Vance, D. E., Nov 11 2005, In : Journal of Biological Chemistry. 280, 45, p. 37798-37802 5 p.

Research output: Contribution to journalArticle

Liver Failure
Choline
Phosphatidylcholines
Liver
Homeostasis
2002
15 Citations (Scopus)

Overexpression of PEMT2 downregulates the PI3K/Akt signaling pathway in rat hepatoma cells

Zou, W., Li, Z., Li, Y. L., Ma, K. L. & Tsui, Z. C., Mar 15 2002, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1581, 1-2, p. 49-56 8 p.

Research output: Contribution to journalArticle

Phosphatidylethanolamine N-Methyltransferase
Phosphatidylinositol 3-Kinases
Hepatocellular Carcinoma
Down-Regulation
Western Blotting
2000
1 Citation (Scopus)
Phosphatidylethanolamine N-Methyltransferase
Ethanolamine
Hepatocytes
Hepatocellular Carcinoma
Immunochemistry

Ras-GTP-Raf complexes and its molecular mechanism in the signal transduction

Li, Z., Zou, W. & Cui, Z. C., 2000, In : Progress in Biochemistry and Biophysics. 27, 4, p. 374 1 p.

Research output: Contribution to journalArticle

Signal transduction
Guanosine Triphosphate
Signal Transduction
Switch Genes
Amplification