Yuri Ann Saito Loftus, MD MPH

Former affiliation
  • 3175 Citations
  • 26 Scopus h-Index
20002019

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Research Output

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2019

Randomised clinical trial: pregabalin vs placebo for irritable bowel syndrome

Saito Loftus, Y. A., Almazar, A. E., Tilkes, K. E., Choung, R. S., Van Norstrand, M. D., Schleck, C. D., Zinsmeister, A. R. & Talley, N. J., Feb 1 2019, In : Alimentary Pharmacology and Therapeutics. 49, 4, p. 389-397 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

SCN5A mutation G615E results in NaV1.5 voltage-gated sodium channels with normal voltage-dependent function yet loss of mechanosensitivity

Strege, P. R., Mercado-Perez, A., Mazzone, A., Saito Loftus, Y. A., Bernard, C. E., Farrugia, G. & Beyder, A., Dec 1 2019, In : Channels (Austin, Tex.). 13, 1, p. 287-298 12 p.

Research output: Contribution to journalArticle

Open Access
2018

American college of gastroenterology monograph on management of irritable bowel syndrome

ACG Task Force on Management of Irritable Bowel Syndrome, Jan 1 2018, In : American Journal of Gastroenterology. 113, S2, p. 1-18 18 p.

Research output: Contribution to journalArticle

52 Scopus citations

Celiac disease is uncommon in irritable bowel syndrome in the USA

Almazar, A. E., Talley, N. J., Larson, J. J., Atkinson, E. J., Murray, J. A. & Saito Loftus, Y. A., Jan 1 2018, In : European Journal of Gastroenterology and Hepatology. 30, 2, p. 149-154 6 p.

Research output: Contribution to journalArticle

Comparison of Lactase Variant MCM6 -13910 C>T Testing and Self-report of Dairy Sensitivity in Patients With Irritable Bowel Syndrome

Almazar, A. E., Chang, J. Y., Larson, J. J., Atkinson, E. J., Locke, G. R., Talley, N. J. & Saito Loftus, Y. A., Jun 16 2018, (Accepted/In press) In : Journal of Clinical Gastroenterology.

Research output: Contribution to journalArticle

3 Scopus citations

Effects of Amitriptyline and Escitalopram on Sleep and Mood in Patients With Functional Dyspepsia

Herrick, L. M., Camilleri, M., Schleck, C. D., Zinsmeister, A. R., Saito Loftus, Y. A. & Talley, N. J., Mar 1 2018, In : Clinical Gastroenterology and Hepatology. 16, 3, p. 401-406.e2

Research output: Contribution to journalArticle

4 Scopus citations

Effects of antidepressants on gastric function in patients with functional dyspepsia

Lacy, B. E., Saito Loftus, Y. A., Camilleri, M., Bouras, E., DiBaise, J. K., Herrick, L. M., Szarka, L., Tilkes, K., Zinsmeister, A. R. & Talley, N. J., Feb 1 2018, In : American Journal of Gastroenterology. 113, 2, p. 216-224 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Irritable bowel syndrome patients have SCN5A channelopathies that lead to decreased Na v 1.5 current and mechanosensitivity

Strege, P. R., Mazzone, A., Bernard, C. E., Neshatian, L., Gibbons, S. J., Saito, Y. A., Tester, D. J., Calvert, M. L., Mayer, E. A., Chang, L., Ackerman, M. J., Beyder, A. & Farrugia, G., Apr 2018, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 314, 4, p. G494-G503

Research output: Contribution to journalArticle

10 Scopus citations

Quantifying Rome symptoms for diagnosis of the irritable bowel syndrome

Chang, J. Y., Almazar, A. E., Richard Locke, G., Larson, J. J., Atkinson, E. J., Talley, N. J. & Saito Loftus, Y. A., Sep 1 2018, In : Neurogastroenterology and Motility. 30, 9, e13356.

Research output: Contribution to journalArticle

2017

Early Infections and the Risk of Irritable Bowel Syndrome: A Case-Control Study

Krajicek, E. J., Almazar, A. E., Larson, J. J., Atkinson, E. J., Talley, N. J. & Saito Loftus, Y. A., Jun 21 2017, (Accepted/In press) In : Journal of Clinical Gastroenterology.

Research output: Contribution to journalArticle

Identification and validation of functional gastrointestinal disorder subtypes using latent class analysis: a population-based study

Zinsmeister, A. R., Herrick, L. M., Saito Loftus, Y. A., Schleck, C. D. & Talley, N. J., Nov 3 2017, (Accepted/In press) In : Scandinavian Journal of Gastroenterology. p. 1-10 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Polymorphisms of 5-HTT LPR and GNβ3 825C>T and Response to Antidepressant Treatment in Functional Dyspepsia: A Study from The Functional Dyspepsia Treatment Trial

Saito Loftus, Y. A., Locke, G. R., Almazar, A. E., Bouras, E. P., Howden, C. W., Lacy, B. E., DiBaise, J. K., Prather, C. M., Abraham, B. P., El-Serag, H. B., Moayyedi, P., Herrick, L. M., Szarka, L., Camilleri, M., Hamilton, F. A., Schleck, C. D., Tilkes, K. E., Zinsmeister, A. R. & Talley, N. J., Mar 14 2017, (Accepted/In press) In : American Journal of Gastroenterology.

Research output: Contribution to journalArticle

9 Scopus citations
2016

A case-control comparison of direct healthcare-provider medical costs of chronic idiopathic constipation and irritable bowel syndrome with constipation in a community-based cohort

Herrick, L. M., Spalding, W. M., Saito Loftus, Y. A., Moriarty, J. & Schleck, C., Nov 10 2016, (Accepted/In press) In : Journal of Medical Economics. p. 1-7 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

Irritable bowel syndrome and the perinatal period: lower birth weight increases the risk

Raslau, D., Herrick, L. M., Locke, G. R., Schleck, C. D., Zinsmeister, A. R., Almazar, A., Talley, N. J. & Saito Loftus, Y. A., Oct 1 2016, In : Neurogastroenterology and Motility. 28, 10, p. 1518-1524 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Reply

FDTT Investigators, Feb 1 2016, In : Gastroenterology. 150, 2, p. 532-533 2 p.

Research output: Contribution to journalArticle

2015

Effect of amitriptyline and escitalopram on functional dyspepsia: A multicenter, randomized controlled study

Talley, N. J., Richard Locke, G., Saito Loftus, Y. A., Almazar, A. E., Bouras, E. P., Howden, C. W., Lacy, B. E., Dibaise, J. K., Prather, C. M., Abraham, B. P., El-Serag, H. B., Moayyedi, P., Herrick, L. M., Szarka, L., Camilleri, M., Hamilton, F. A., Schleck, C. D., Tilkes, K. E. & Zinsmeister, A. R., Aug 1 2015, In : Gastroenterology. 149, 2, p. 340-349.e2

Research output: Contribution to journalArticle

121 Scopus citations

Irritable bowel syndrome: New and emerging treatments

Halland, M. & Saito Loftus, Y. A., Jun 18 2015, In : BMJ (Online). 350, h1622.

Research output: Contribution to journalArticle

21 Scopus citations

Prevalence and risk factors for dysphagia: A USA community study

Cho, S. Y., Choung, R. S., Saito, Y. A., Schleck, C. D., Zinsmeister, A. R., Locke, G. R. & Talley, N. J., Feb 1 2015, In : Neurogastroenterology and Motility. 27, 2, p. 212-219 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

The effect of dietary intervention on irritable bowel syndrome: A systematic review

Moayyedi, P., Quigley, E. M. M., Lacy, B. E., Lembo, A. J., Saito Loftus, Y. A., Schiller, L. R., Soffer, E. E., Spiegel, B. M. R. & Ford, A. C., Aug 20 2015, In : Clinical and Translational Gastroenterology. 6, 8, e107.

Research output: Contribution to journalArticle

35 Scopus citations
2014

A case-control study of childhood trauma in the development of irritable bowel syndrome

Halland, M., Almazar, A., Lee, R., Atkinson, E., Larson, J., Talley, N. J. & Saito, Y. A., Jul 2014, In : Neurogastroenterology and Motility. 26, 7, p. 990-998 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

American college of gastroenterology monograph on the management of irritable bowel syndrome and chronic idiopathic constipation

Ford, A. C., Moayyedi, P., Lacy, B. E., Lembo, A. J., Saito, Y. A., Schiller, L. R., Soffer, E. E., Spiegel, B. M. R. & Quigley, E. M. M., Aug 2014, In : American Journal of Gastroenterology. 109, SUPPL. 1, p. S2-S26

Research output: Contribution to journalArticle

329 Scopus citations

Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis

Ford, A. C., Quigley, E. M. M., Lacy, B. E., Lembo, A. J., Saito, Y. A., Schiller, L. R., Soffer, E. E., Spiegel, B. M. R. & Moayyedi, P., Oct 1 2014, In : The American Journal of Gastroenterology. 109, 10, p. 1547-1562 16 p.

Research output: Contribution to journalArticle

357 Scopus citations
22 Scopus citations

Loss-of-function of the voltage-gated sodium channel NaV1.5 (Channelopathies) in patients with irritable bowel syndrome

Beyder, A., Mazzone, A., Strege, P. R., Tester, D. J., Saito, Y. A., Bernard, C. E., Enders, F. T., Ek, W. E., Schmidt, P. T., Dlugosz, A., Lindberg, G., Karling, P., Ohlsson, B., Gazouli, M., Nardone, G., Cuomo, R., Usai-Satta, P., Galeazzi, F., Neri, M., Portincasa, P. & 8 others, Bellini, M., Barbara, G., Camilleri, M., Locke, G. R., Talley, N. J., D'Amato, M., Ackerman, M. J. & Farrugia, G., Jun 2014, In : Gastroenterology. 146, 7, p. 1659-1668 10 p.

Research output: Contribution to journalArticle

63 Scopus citations
2012

The role of 5-HTT LPR and GNβ3 825C>T polymorphisms and gene-environment interactions in irritable bowel syndrome (IBS)

Saito, Y. A., Larson, J. J., Atkinson, E. J., Ryu, E., Almazar, A. E., Petersen, G. M. & Talley, N. J., Oct 1 2012, In : Digestive diseases and sciences. 57, 10, p. 2650-2657 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
2011

Characteristics of acute pain attacks in patients with irritable bowel syndrome meeting Rome III criteria

Hellström, P. M., Saito, Y. A., Bytzer, P., Tack, J., Mueller-Lissner, S. & Chang, L., Jul 1 2011, In : American Journal of Gastroenterology. 106, 7, p. 1299-1307 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Clinical predictors of small intestinal bacterial overgrowth by duodenal aspirate culture

Choung, R. S., Ruff, K. C., Malhotra, A., Herrick, L., Locke, G. R., Harmsen, W. S., Zinsmeister, A. R., Talley, N. J. & Saito, Y. A., May 1 2011, In : Alimentary Pharmacology and Therapeutics. 33, 9, p. 1059-1067 9 p.

Research output: Contribution to journalArticle

75 Scopus citations
2010

A randomized, double-blind, placebo-controlled trial of st john's wort for treating irritable bowel syndrome

Saito, Y. A., Rey, E., Almazar-Elder, A. E., Harmsen, W. S., Zinsmeister, A. R., Locke, G. R. & Talley, N. J., Jan 1 2010, In : American Journal of Gastroenterology. 105, 1, p. 170-177 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Familial aggregation of irritable bowel syndrome: A family case-control study

Saito, Y. A., Petersen, G. M., Larson, J. J., Atkinson, E. J., Fridley, B. L., De Andrade, M., Locke, G. R., Zimmerman, J. M., Almazar-Elder, A. E. & Talley, N. J., Apr 1 2010, In : American Journal of Gastroenterology. 105, 4, p. 833-841 9 p.

Research output: Contribution to journalArticle

66 Scopus citations
2009

Sodium channel mutation in irritable bowel syndrome: Evidence for an ion channelopathy

Saito, Y. A., Strege, P. R., Tester, D. J., Locke, G. R., Talley, N. J., Bernard, C. E., Rae, J. L., Makielski, J. C., Ackerman, M. J. & Farrugia, G., Feb 1 2009, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 296, 2, p. G211-G218

Research output: Contribution to journalArticle

85 Scopus citations
2008

Irritable bowel syndrome aggregates strongly in families: A family-based case-control study

Saito, Y. A., Zimmerman, J. M., S. Harmsen, W., De Andrade, M., Locke, G. R., Petersen, G. M. & Talley, N. J., Jul 1 2008, In : Neurogastroenterology and Motility. 20, 7, p. 790-797 8 p.

Research output: Contribution to journalArticle

50 Scopus citations
2007

A genetic association study of 5-HTT LPR and GNβ3 C825T polymorphisms with irritable bowel syndrome

Saito, Y. A., Locke, G. R., Zimmerman, J. M., Holtmann, G., Slusser, J. P., De Andrade, M., Petersen, G. M. & Talley, N. J., Jun 1 2007, In : Neurogastroenterology and Motility. 19, 6, p. 465-470 6 p.

Research output: Contribution to journalArticle

55 Scopus citations
2006

Is There an Association Between GNβ3-C825T Genotype and Lower Functional Gastrointestinal Disorders?

Andresen, V., Camilleri, M., Kim, H. J., Stephens, D. A., Carlson, P. J., Talley, N. J., Saito, Y. A., Urrutia, R. & Zinsmeister, A. R., Jul 2006, In : Gastroenterology. 130, 7, p. 1985-1994 10 p.

Research output: Contribution to journalArticle

52 Scopus citations
2005

Diet and functional gastrointestinal disorders: A population-based case-control study

Saito, Y. A., Locke, G. R., Weaver, A. L., Zinsmeister, A. R. & Talley, N. J., Dec 1 2005, In : American Journal of Gastroenterology. 100, 12, p. 2743-2748 6 p.

Research output: Contribution to journalArticle

117 Scopus citations

The genetics of irritable bowel syndrome

Saito, Y. A., Petersen, G. M., Locke, G. R. & Talley, N. J., Nov 2005, In : Clinical Gastroenterology and Hepatology. 3, 11, p. 1057-1065 9 p.

Research output: Contribution to journalArticle

57 Scopus citations
2004

Effects of multidisciplinary education on outcomes in patients with irritable bowel syndrome

Saito, Y. A., Prather, C. M., Van Dyke, C. T., Fett, S., Zinsmeister, A. R. & Locke, G. R., Jul 1 2004, In : Clinical Gastroenterology and Hepatology. 2, 7, p. 576-584 9 p.

Research output: Contribution to journalArticle

49 Scopus citations
2003

The effect of new diagnostic criteria for irritable bowel syndrome on community prevalence estimates

Saito, Y. A., Talley, N. J., Melton, L. J., Fett, S., Zinsmeister, A. R. & Locke, G. R., Dec 1 2003, In : Neurogastroenterology and Motility. 15, 6, p. 687-694 8 p.

Research output: Contribution to journalArticle

64 Scopus citations
2002

Origin of adenocarcinoma in a transplanted liver determined by microsatellite analysis

Kakar, S., Burgart, L. J., Charlton, M. R., Saito, Y., Halling, K. & Thibodeau, S. N., Jan 1 2002, In : Human Pathology. 33, 4, p. 435-436 2 p.

Research output: Contribution to journalArticle

15 Scopus citations
2000

A comparison of the Rome and Manning criteria for case identification in epidemiological investigations of irritable bowel syndrome

Saito, Y. A., Locke, G. R., Talley, N. J., Zinsmeister, A. R., Fett, S. L. & Melton, L. J., Oct 30 2000, In : American Journal of Gastroenterology. 95, 10, p. 2816-2824 9 p.

Research output: Contribution to journalArticle

186 Scopus citations