Yuri Ann Saito Loftus, MD MPH

Former affiliation
  • 3229 Citations
  • 26 Scopus h-Index
20002019

Research output per year

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Research Output

2019

Comparison of Lactase Variant MCM6-13910 C>T Testing and Self-report of Dairy Sensitivity in Patients with Irritable Bowel Syndrome

Almazar, A. E., Chang, J. Y., Larson, J. J., Atkinson, E. J., Locke, G. R., Talley, N. J. & Saito, Y. A., Jul 1 2019, In : Journal of clinical gastroenterology. 53, 6, p. E227-E231

Research output: Contribution to journalArticle

3 Scopus citations

Randomised clinical trial: pregabalin vs placebo for irritable bowel syndrome

Saito Loftus, Y. A., Almazar, A. E., Tilkes, K. E., Choung, R. S., Van Norstrand, M. D., Schleck, C. D., Zinsmeister, A. R. & Talley, N. J., Feb 1 2019, In : Alimentary Pharmacology and Therapeutics. 49, 4, p. 389-397 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

SCN5A mutation G615E results in NaV1.5 voltage-gated sodium channels with normal voltage-dependent function yet loss of mechanosensitivity

Strege, P. R., Mercado-Perez, A., Mazzone, A., Saito, Y. A., Bernard, C. E., Farrugia, G. & Beyder, A., Jan 1 2019, In : Channels. 13, 1, p. 287-298 12 p.

Research output: Contribution to journalArticle

Open Access
2018

American college of gastroenterology monograph on management of irritable bowel syndrome

ACG Task Force on Management of Irritable Bowel Syndrome, Jan 1 2018, In : American Journal of Gastroenterology. 113, S2, p. 1-18 18 p.

Research output: Contribution to journalArticle

56 Scopus citations

A Systematic Review and Meta-Analysis Evaluating the Efficacy of a Gluten-Free Diet and a Low FODMAPs Diet in Treating Symptoms of Irritable Bowel Syndrome

Dionne, J., Ford, A. C., Yuan, Y., Chey, W. D., Lacy, B. E., Saito, Y. A., Quigley, E. M. M. & Moayyedi, P., Sep 1 2018, In : American Journal of Gastroenterology. 113, 9, p. 1290-1300 11 p.

Research output: Contribution to journalReview article

63 Scopus citations

Celiac disease is uncommon in irritable bowel syndrome in the USA

Almazar, A. E., Talley, N. J., Larson, J. J., Atkinson, E. J., Murray, J. A. & Saito Loftus, Y. A., Jan 1 2018, In : European Journal of Gastroenterology and Hepatology. 30, 2, p. 149-154 6 p.

Research output: Contribution to journalArticle

Effects of Amitriptyline and Escitalopram on Sleep and Mood in Patients With Functional Dyspepsia

Herrick, L. M., Camilleri, M., Schleck, C. D., Zinsmeister, A. R., Saito Loftus, Y. A. & Talley, N. J., Mar 1 2018, In : Clinical Gastroenterology and Hepatology. 16, 3, p. 401-406.e2

Research output: Contribution to journalArticle

4 Scopus citations

Effects of antidepressants on gastric function in patients with functional dyspepsia

Lacy, B. E., Saito Loftus, Y. A., Camilleri, M., Bouras, E., DiBaise, J. K., Herrick, L. M., Szarka, L., Tilkes, K., Zinsmeister, A. R. & Talley, N. J., Feb 1 2018, In : American Journal of Gastroenterology. 113, 2, p. 216-224 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Irritable bowel syndrome patients have SCN5A channelopathies that lead to decreased Na v 1.5 current and mechanosensitivity

Strege, P. R., Mazzone, A., Bernard, C. E., Neshatian, L., Gibbons, S. J., Saito, Y. A., Tester, D. J., Calvert, M. L., Mayer, E. A., Chang, L., Ackerman, M. J., Beyder, A. & Farrugia, G., Apr 2018, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 314, 4, p. G494-G503

Research output: Contribution to journalArticle

11 Scopus citations

Quantifying Rome symptoms for diagnosis of the irritable bowel syndrome

Chang, J. Y., Almazar, A. E., Richard Locke, G., Larson, J. J., Atkinson, E. J., Talley, N. J. & Saito Loftus, Y. A., Sep 1 2018, In : Neurogastroenterology and Motility. 30, 9, e13356.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Early Infections and the Risk of Irritable Bowel Syndrome: A Case-Control Study

Krajicek, E. J., Almazar, A. E., Larson, J. J., Atkinson, E. J., Talley, N. J. & Saito Loftus, Y. A., Jun 21 2017, (Accepted/In press) In : Journal of Clinical Gastroenterology.

Research output: Contribution to journalArticle

Identification and validation of functional gastrointestinal disorder subtypes using latent class analysis: a population-based study

Zinsmeister, A. R., Herrick, L. M., Saito Loftus, Y. A., Schleck, C. D. & Talley, N. J., Nov 3 2017, (Accepted/In press) In : Scandinavian Journal of Gastroenterology. p. 1-10 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Polymorphisms of 5-HTT LPR and GNβ3 825C>T and Response to Antidepressant Treatment in Functional Dyspepsia: A Study from The Functional Dyspepsia Treatment Trial

Saito Loftus, Y. A., Locke, G. R., Almazar, A. E., Bouras, E. P., Howden, C. W., Lacy, B. E., DiBaise, J. K., Prather, C. M., Abraham, B. P., El-Serag, H. B., Moayyedi, P., Herrick, L. M., Szarka, L., Camilleri, M., Hamilton, F. A., Schleck, C. D., Tilkes, K. E., Zinsmeister, A. R. & Talley, N. J., Mar 14 2017, (Accepted/In press) In : American Journal of Gastroenterology.

Research output: Contribution to journalArticle

9 Scopus citations
2016

A case-control comparison of direct healthcare-provider medical costs of chronic idiopathic constipation and irritable bowel syndrome with constipation in a community-based cohort

Herrick, L. M., Spalding, W. M., Saito Loftus, Y. A., Moriarty, J. & Schleck, C., Nov 10 2016, (Accepted/In press) In : Journal of Medical Economics. p. 1-7 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Irritable bowel syndrome and the perinatal period: lower birth weight increases the risk

Raslau, D., Herrick, L. M., Locke, G. R., Schleck, C. D., Zinsmeister, A. R., Almazar, A., Talley, N. J. & Saito Loftus, Y. A., Oct 1 2016, In : Neurogastroenterology and Motility. 28, 10, p. 1518-1524 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Reply

FDTT Investigators, Feb 1 2016, In : Gastroenterology. 150, 2, p. 532-533 2 p.

Research output: Contribution to journalArticle

2015

Effect of amitriptyline and escitalopram on functional dyspepsia: A multicenter, randomized controlled study

Talley, N. J., Richard Locke, G., Saito, Y. A., Almazar, A. E., Bouras, E. P., Howden, C. W., Lacy, B. E., Dibaise, J. K., Prather, C. M., Abraham, B. P., El-Serag, H. B., Moayyedi, P., Herrick, L. M., Szarka, L. A., Camilleri, M., Hamilton, F. A., Schleck, C. D., Tilkes, K. E. & Zinsmeister, A. R., Aug 1 2015, In : Gastroenterology. 149, 2, p. 340-349.e2

Research output: Contribution to journalArticle

124 Scopus citations

Irritable bowel syndrome: New and emerging treatments

Halland, M. & Saito, Y. A., Jun 18 2015, In : BMJ (Online). 350, h1622.

Research output: Contribution to journalArticle

22 Scopus citations

Letter: Role of GNβ3 polymorphisms in oesophageal adenocarcinoma and gastroesophageal reflux disease

Brummond, N. R., Saito, Y. A., Locke, G. R., Larson, J. J., Atkinson, E. J., Romero, Y. & Talley, N. J., Mar 1 2015, In : Alimentary Pharmacology and Therapeutics. 41, 6, p. 600-601 2 p.

Research output: Contribution to journalLetter

2 Scopus citations

Prevalence and risk factors for dysphagia: A USA community study

Cho, S. Y., Choung, R. S., Saito, Y. A., Schleck, C. D., Zinsmeister, A. R., Locke, G. R. & Talley, N. J., Feb 1 2015, In : Neurogastroenterology and Motility. 27, 2, p. 212-219 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

The effect of dietary intervention on irritable bowel syndrome: A systematic review

Moayyedi, P., Quigley, E. M. M., Lacy, B. E., Lembo, A. J., Saito Loftus, Y. A., Schiller, L. R., Soffer, E. E., Spiegel, B. M. R. & Ford, A. C., Aug 20 2015, In : Clinical and Translational Gastroenterology. 6, 8, e107.

Research output: Contribution to journalArticle

35 Scopus citations
2014

A case-control study of childhood trauma in the development of irritable bowel syndrome

Halland, M., Almazar, A., Lee, R., Atkinson, E., Larson, J., Talley, N. J. & Saito, Y. A., Jul 2014, In : Neurogastroenterology and Motility. 26, 7, p. 990-998 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

American college of gastroenterology monograph on the management of irritable bowel syndrome and chronic idiopathic constipation

Ford, A. C., Moayyedi, P., Lacy, B. E., Lembo, A. J., Saito, Y. A., Schiller, L. R., Soffer, E. E., Spiegel, B. M. R. & Quigley, E. M. M., Aug 2014, In : American Journal of Gastroenterology. 109, SUPPL. 1, p. S2-S26

Research output: Contribution to journalArticle

336 Scopus citations

Effect of antidepressants and psychological therapies, including hypnotherapy, in irritable bowel syndrome: systematic review and meta-analysis.

Ford, A. C., Quigley, E. M. M., Lacy, B. E., Lembo, A. J., Saito, Y. A., Schiller, L. R., Soffer, E. E., Spiegel, B. M. R. & Moayyedi, P., Sep 2014, In : The American Journal of Gastroenterology. 109, 9, p. 1350-1365; quiz 1366

Research output: Contribution to journalReview article

254 Scopus citations

Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis

Ford, A. C., Quigley, E. M. M., Lacy, B. E., Lembo, A. J., Saito, Y. A., Schiller, L. R., Soffer, E. E., Spiegel, B. M. R. & Moayyedi, P., Oct 1 2014, In : The American Journal of Gastroenterology. 109, 10, p. 1547-1562 16 p.

Research output: Contribution to journalArticle

362 Scopus citations

Epidemiology of Irritable Bowel Syndrome

Choung, R. S. & Saito Loftus, Y. A., Jan 13 2014, GI Epidemiology: Diseases and Clinical Methodology: Second Edition. Wiley Blackwell, p. 222-234 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Genome-wide association study identifies two novel genomic regions in irritable bowel syndrome

Holliday, E. G., Attia, J., Hancock, S., Koloski, N., McEvoy, M., Peel, R., D'Amato, M., Agréus, L., Nyhlin, H., Andreasson, A., Almazar, A. E., Saito, Y. A., Scott, R. J. & Talley, N. J., May 2014, In : American Journal of Gastroenterology. 109, 5, p. 770-772 3 p.

Research output: Contribution to journalLetter

11 Scopus citations

GI Epidemiology: Diseases and Clinical Methodology: Second Edition

Talley, N. J., Locke, G. R., Moayyedi, P., West, J., Ford, A. C. & Saito Loftus, Y. A., Jan 13 2014, Wiley Blackwell. 413 p.

Research output: Book/ReportBook

1 Scopus citations

How to Do Genetic and Molecular Epidemiologic Research

Saito Loftus, Y. A., Jan 13 2014, GI Epidemiology: Diseases and Clinical Methodology: Second Edition. Wiley Blackwell, p. 98-105 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

23 Scopus citations

Loss-of-function of the voltage-gated sodium channel NaV1.5 (Channelopathies) in patients with irritable bowel syndrome

Beyder, A., Mazzone, A., Strege, P. R., Tester, D. J., Saito, Y. A., Bernard, C. E., Enders, F. T., Ek, W. E., Schmidt, P. T., Dlugosz, A., Lindberg, G., Karling, P., Ohlsson, B., Gazouli, M., Nardone, G., Cuomo, R., Usai-Satta, P., Galeazzi, F., Neri, M., Portincasa, P. & 8 others, Bellini, M., Barbara, G., Camilleri, M., Locke, G. R., Talley, N. J., D'Amato, M., Ackerman, M. J. & Farrugia, G., Jun 2014, In : Gastroenterology. 146, 7, p. 1659-1668 10 p.

Research output: Contribution to journalArticle

65 Scopus citations

The effect of fiber supplementation on irritable bowel syndrome: a systematic review and meta-analysis.

Moayyedi, P., Quigley, E. M. M., Lacy, B. E., Lembo, A. J., Saito, Y. A., Schiller, L. R., Soffer, E. E., Spiegel, B. M. R. & Ford, A. C., Sep 2014, In : The American Journal of Gastroenterology. 109, 9, p. 1367-1374 8 p.

Research output: Contribution to journalReview article

116 Scopus citations
2012

The role of 5-HTT LPR and GNβ3 825C>T polymorphisms and gene-environment interactions in irritable bowel syndrome (IBS)

Saito, Y. A., Larson, J. J., Atkinson, E. J., Ryu, E., Almazar, A. E., Petersen, G. M. & Talley, N. J., Oct 1 2012, In : Digestive diseases and sciences. 57, 10, p. 2650-2657 8 p.

Research output: Contribution to journalArticle

20 Scopus citations
2011

Characteristics of acute pain attacks in patients with irritable bowel syndrome meeting Rome III criteria

Hellström, P. M., Saito, Y. A., Bytzer, P., Tack, J., Mueller-Lissner, S. & Chang, L., Jul 1 2011, In : American Journal of Gastroenterology. 106, 7, p. 1299-1307 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Clinical predictors of small intestinal bacterial overgrowth by duodenal aspirate culture

Choung, R. S., Ruff, K. C., Malhotra, A., Herrick, L., Locke, G. R., Harmsen, W. S., Zinsmeister, A. R., Talley, N. J. & Saito, Y. A., May 1 2011, In : Alimentary Pharmacology and Therapeutics. 33, 9, p. 1059-1067 9 p.

Research output: Contribution to journalArticle

76 Scopus citations

Clinical predictors of small intestinal bacterial overgrowth by duodenal aspirate culture: Authors' reply

Saito, Y. A., Choung, R. S., Zinsmeister, A. R. & Talley, N. J., Jun 1 2011, In : Alimentary Pharmacology and Therapeutics. 33, 12, p. 1379-1380 2 p.

Research output: Contribution to journalLetter

The Role of Genetics in IBS

Saito, Y. A., Mar 2011, In : Gastroenterology Clinics of North America. 40, 1, p. 45-67 23 p.

Research output: Contribution to journalReview article

75 Scopus citations
2010

A randomized, double-blind, placebo-controlled trial of st john's wort for treating irritable bowel syndrome

Saito, Y. A., Rey, E., Almazar-Elder, A. E., Harmsen, W. S., Zinsmeister, A. R., Locke, G. R. & Talley, N. J., Jan 1 2010, In : American Journal of Gastroenterology. 105, 1, p. 170-177 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Familial aggregation of irritable bowel syndrome: A family case-control study

Saito, Y. A., Petersen, G. M., Larson, J. J., Atkinson, E. J., Fridley, B. L., De Andrade, M., Locke, G. R., Zimmerman, J. M., Almazar-Elder, A. E. & Talley, N. J., Apr 1 2010, In : American Journal of Gastroenterology. 105, 4, p. 833-841 9 p.

Research output: Contribution to journalArticle

66 Scopus citations

Genetic Approaches to Functional Gastrointestinal Disorders

Saito, Y. A., Mitra, N. & Mayer, E. A., Apr 2010, In : Gastroenterology. 138, 4, p. 1276-1285 10 p.

Research output: Contribution to journalReview article

64 Scopus citations
2009

AJG series: Molecular biology for clinicians

Saito, Y. A. & Talley, N. J., Oct 1 2009, In : American Journal of Gastroenterology. 104, 10, p. 2583-2587 5 p.

Research output: Contribution to journalReview article

3 Scopus citations

Sodium channel mutation in irritable bowel syndrome: Evidence for an ion channelopathy

Saito, Y. A., Strege, P. R., Tester, D. J., Locke, G. R., Talley, N. J., Bernard, C. E., Rae, J. L., Makielski, J. C., Ackerman, M. J. & Farrugia, G., Feb 2009, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 296, 2, p. G211-G218

Research output: Contribution to journalArticle

86 Scopus citations
2008

Genes and irritable bowel syndrome: Is there a link?

Saito, Y. A., Dec 1 2008, In : Current gastroenterology reports. 10, 4, p. 355-362 8 p.

Research output: Contribution to journalReview article

5 Scopus citations

Genetic Epidemiology

Saito, Y. A. & Petersen, G. M., Apr 15 2008, GI Epidemiology. Blackwell Publishing Ltd, p. 97-102 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Genetics of irritable bowel syndrome

Saito, Y. A. & Talley, N. J., Aug 1 2008, In : American Journal of Gastroenterology. 103, 8, p. 2100-2104 5 p.

Research output: Contribution to journalReview article

48 Scopus citations

GI Epidemiology

Talley, N. J., Locke, G. R. & Saito, Y. A., Apr 15 2008, Blackwell Publishing Ltd. 270 p.

Research output: Book/ReportBook

6 Scopus citations

Irritable Bowel Syndrome

Saito, Y. A., Talley, N. J. & Locke, G. R., Apr 15 2008, GI Epidemiology. Blackwell Publishing Ltd, p. 176-183 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Irritable bowel syndrome aggregates strongly in families: A family-based case-control study

Saito, Y. A., Zimmerman, J. M., S. Harmsen, W., De Andrade, M., Locke, G. R., Petersen, G. M. & Talley, N. J., Jul 1 2008, In : Neurogastroenterology and Motility. 20, 7, p. 790-797 8 p.

Research output: Contribution to journalArticle

51 Scopus citations

Pharmacogenomics in gastrointestinal disorders

Camilleri, M. & Saito Loftus, Y. A., 2008, Methods in Molecular Biology. Humana Press, Vol. 448. p. 395-412 18 p. (Methods in Molecular Biology; vol. 448).

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Scopus citations